Max Planck Institute of Immunbiology and Epigenetics, Freiburg
Developmental and Evolutionary Biology & Genetics Immunobiology and Infection Biology & Medicine
Type of Job
Job offer from May 15, 2017
The Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany offers one Postdoctoral Position in the Group of Andrea Pichler working on the posttranslational modification with SUMO, the small ubiquitin related modifier.
The MPI in Freiburg is an international research institute at the cross-roads of Southern Germany, Switzerland and France. The working language is English. State-of-the-art infrastructure and service units, including transgenesis, mass spectrometry, proteomics, flow cytometry, fly and imaging facilities are available.
Our Institute investigates the molecular basis of the immune response and other topics of the developmental biology, such as the origin and differentiation of the immune cells as well as the development of vertebrate embryo. Another main focus of the Institute is Epigenetic. This area deals with inheritable traits, which are not caused by changes in the DNA sequence.
The research focus of the Pichler laboratory is to study the regulation of SUMO conjugation. We recently identified a vertebrate specific novel family of SUMO E3 ligases, the ZNF451 family (Eisenhardt et al NSMB 2015, Cappadocia et al, NSMB 2015), and now aim to gain insights into their biological function in mammalian cells. Initial findings point to functions in DNA damage repair, proteasomal inhibition and DNA replication. We are using multidisciplinary approaches combining cell biology, biochemistry, enzymology as well as structural biology.
We are looking for an enthusiastic, highly-motivated, science-driven open minded scientist to join our team to unravel the cellular and molecular mechanisms regulated by SUMO conjugation.
Postdoctoral applicants should have a PhD in biology or equivalent doctoral degree with proven research experience in molecular biology, cell biology and/or biochemistry. Prior experience working on DNA replication, DNA damage repair or the ubiquitin system is an advantage. Furthermore, the ability to work in a team, and communication skills are an asset.
The position is available for an initial one-year appointment with the possibility of extension. Salary will be based on previous experience according to TVöD guidelines (collective wage agreement for the public service).
Handicapped applicants with equal qualifications will be given preferential treatment. The Max Planck Society seeks to increase the number of women in areas, where they are underrepresented, and therefore explicitly encourages women to apply. A childcare facility is directly attached to the institute.
Have we sparked your interest? Please submit your complete application, including a statement of research interests and a CV directly via our online application portal until May 29th, 2017.
Max-Planck-Institute of Immunobiology and Epigenetics