Molecular Immunology (University/MPI-IE)
The department of Molecular Immunology is a joint department of the Max Planck Institute of Immunobiology and Epigenetics (MPI-IE) and the University of Freiburg. Central for the research group is a better understanding of the organization and regulation of intracellular signaling pathways in normal and diseased lymphocytes. The laboratory headed by Michael Reth investigates signaling processes in B cells. Applying and developing new approaches in super-resolution microscopy and proximity analysis they study the nano-scale organization of the B cell antigen receptor and its coreceptors on the surface of B lymphocytes. The group also employs synthetic biology approaches to rebuild signaling pathways for a better understanding and studies mechanism of B cell selection and survival with the Cre/loxP technique.
In collaboration with the University of Freiburg and the MPI-IE, the department organizes the advanced study program “Molecular Immunology”. This program has become very popular since its establishment in 1997. It is now part of the Bachelor-Master Study Program in Biology of the Faculty of Biology and attracts students from Freiburg and many other universities.