Publications

Clapes, T.; Polyzou, A.; Prater, P.; Sagar; Morales-Hernández, A.; Ferrarini, M. G.; Kehrer, N.; Lefkopoulos, S.; Bergo, V.; Hummel, B. et al.; Obier, N.; Maticzka, D.; Bridgeman, A.; Herman, J. S.; Ilik, I.; Klaeylé, L.; Rehwinkel, J.; McKinney-Freeman, S.; Backofen, R.; Akhtar, A.; Cabezas-Wallscheid, N.; Sawarkar, R.; Rebollo, R.; Grün, D.; Trompouki, E.: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration. Nature Cell Biology (2021)

Tiago, T.; Hummel, B.; Morelli, F. F.; Basile, V.; Vinet, J.; Galli, V.; Mediani, L.; Antoniani, F.; Pomella, S.; Cassandri, M. et al.; Garone, M. G.; Silvestri, B.; Cimino, M.; Cenacchi, G.; Costa, R.; Mouly, V.; Poser, I.; Yeger-Lotem, E.; Rosa, A.; Alberti, S.; Rota, R.; Ben-Zvi, A.; Sawarkar, R.; Carra, S.: Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor. Cell Death and Disease 12, p. 452 (2021)

Rawat, P.; Boehning, M.; Hummel, B.; Aprile-Garcia, F.; Pandit, A. S.; Eisenhardt, N.; Khavaran, A.; Niskanen, E.; Vos, S. M.; Palvimo, J. J. et al.; Pichler, A.; Cramer, P.; Sawarkar, R.: Stress-induced nuclear condensation of NELF drives transcriptional downregulation. Molecular Cell 81, pp. 1013 - 1026 (2021)

Antonova, A.; Hummel, B.; Khavaran, A.; Redhaber, D. M.; Aprile-Garcia, F.; Rawat, P.; Gundel, K.; Schneck, M.; Hansen, E. C.; Mitschke, J. et al.; Mittler, G.; Miething, C.; Sawarkar, R.: Heat-Shock Protein 90 Controls the Expression of Cell-Cycle Genes by Stabilizing Metazoan-Specific Host-Cell Factor HCFC1. Cell Reports 29, pp. 1645 - 1659 (2019)

Hörner, M.; Raute, K.; Hummel, B.; Madl, J.; Creusen, G.; Thomas, O. S.; Christen, E. H.; Hotz, N.; Gübeli, R. J.; Engesser, R. et al.; Rebmann, B.; Lauer, J.; Rolauffs, B.; Timmer, J.; Schamel, W. W. A.; Pruszak, J.; Römer, W.; Zurbriggen, M. D.; Friedrich, C.; Walther, A.; Minguet, S.; Sawarkar, R.; Weber, W.: Phytochrome-Based Extracellular Matrix with Reversibly Tunable mechanical Properties. Advanced Materials 31, p. e1806727 (2019)

Aprile-Garcia, F.; Parul, T.; Hummel, B.; Khavaran, A.; Sawarkar, R.: Nascent-protein ubiquitination is required for heat shock-induced gene downregulation in human cells. Nature Structural and Molecular Biology 26, pp. 137 - 146 (2019)

Sawarkar, R.; Scherz‐Shouval, R.; Denzel, M. S.; Saarikangas, J.: Chaperoning junior faculty: Institutional support and guidance can relieve challenges for early-career group leaders and imporove academic performance. EMBO Reports 20, p. e47163 (2019)

Vincenz-Donnelly, L.; Holthusen, H.; Körner, R.; Hansen, E. C.; Presto, J.; Johansson, J.; Sawarkar, R.; Hartl, F. U.; Hipp, M. S.: High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins. The EMBO Journal 37 (3), pp. 337 - 350 (2018)

Irmak, D.; Fatima, A.; Gutiérrez-Garcia, R.; Rinschen, M. M.; Wagle, P.; Altmüller, J.; Arrigoni, L.; Hummel, B.; Klein, C.; Frese, C. K. et al.; Sawarkar, R.; Rada-Iglesias, A.; Vilchez, D.: Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations. Human Molecular Genetics 27, pp. 4117 - 4134 (2018)

Hummel, B.; Hansen, E. C.; Yoveva, A.; Aprile-Garcia, F.; Hussong, R.; Sawarkar, R.: The evolutionary capacitor HSP90 buffers the regulatory effects of mammalian endogenous retroviruses. Nature Structural and Molecular Biology 24, pp. 234 - 242 (2017)

Friedensohn, S.; Sawarkar, R.: Cis-regulatory variation: significance in biomedicine and evolution. Cell and Tissue Research 356, pp. 495 - 505 (2014)

Sawarkar, R.; Paro, R.: Hsp90@chromatin.nucleus: an emerging hub of a networker. Trends in Cell Biology 23, pp. 193 - 201 (2013)

Sawarkar, R.; Sievers, C.; Paro, R.: Hsp90 globally targets paused RNA polymerase to regulate gene expression in response to environmental stimuli. Cell 149, pp. 807 - 818 (2012)

Sievers, C.; Schlumpf, T.; Sawarkar, R.; Comoglio, F.; Paro, R.: Mixture models and wavelet transforms reveal high confidence RNA-protein interaction sites in MoV10PAR-CLIP data. Nucleic Acids Research (London) 40, p. e160 (2012)

Sawarkar, R.; Paro, R.: Heat shock protein 90: a capacitor or a mutator? Journal of Biosciences 35, pp. 163 - 165 (2010)

Sawarkar, R.; Paro, R.: Interpretation of developmental signaling at chromatin: the Polycomb perspective. Developmental Cell 19, pp. 651 - 661 (2010)

Yoveva, A.; Sawarkar, R.: Chromatin Immunoprecipitation (ChIP) of Heat Shock Protein 90 (Hsp90). In: Methods in Molecular Biology, Vol. 1709, pp. 221 - 231. Springer Science + Business Media (2017)

Preparing junior faculty for success.