My research focuses on the function of Ebf1 in B cell development. Ebf1 is early B cell factor 1. It is a key transcriptional factor during B cell development. Deleting Ebf1 will block the cell at early Pro-B cell stage. But the molecular mechanism how Ebf1 works in B lymphopoiesis is not clear enough. So in my research we hope to find out some key factors which could interact with Ebf1 and regulate B cell development.