Nadim Aizarani

from Beirut, Lebanon
IMPRS fellow since April 2016 in Grün lab
Research interestsOne of the most distinctive and challenging properties of cancer is resistance, which can be an outcome of cellular heterogeneity. Most of the therapies for cancer are not selective enough and are one-dimensional in terms of their targets; this is sometimes not enough to eradicate some cancer cells that are found in a highly heterogeneous and advanced-stage tumor. Identifying and characterizing distinct cell types and populations in normal tissue and cancer on the single cell level is essential in order to resolve and understand tumor heterogeneity and evolution and identify novel gene networks and signaling pathways for targeted therapy. During my PhD, I plan to resolve cellular heterogeneity in normal and cancerous tissue using single cell analysis.

Research interests
One of the most distinctive and challenging properties of cancer is resistance, which can be an outcome of cellular heterogeneity. Most of the therapies for cancer are not selective enough and are one-dimensional in terms of their targets; this is sometimes not enough to eradicate some cancer cells that are found in a highly heterogeneous and advanced-stage tumor. Identifying and characterizing distinct cell types and populations in normal tissue and cancer on the single cell level is essential in order to resolve and understand tumor heterogeneity and evolution and identify novel gene networks and signaling pathways for targeted therapy. During my PhD, I plan to resolve cellular heterogeneity in normal and cancerous tissue using single cell analysis.
 
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