Nikki van Teijlingen Bakker

from The Netherlands
IMPRS fellow since October 2017 in Edward Pearce lab
Research interestsMacrophages can become activated in response to IL-4 (M(IL-4)), playing important roles in wound healing and alternatively, parasitic infections. Phenotypical alterations induced by IL-4 stimulation, include a shift in metabolism characterized by increased fatty acid oxidation (FAO), when compared to resting (MO) macrophages. I therefore aim to elucidate the role of  FAO in alternative macrophage activation, which will  contribute to the fundamental understanding of macrophage biology and metabolism.

Research interests
Macrophages can become activated in response to IL-4 (M(IL-4)), playing important roles in wound healing and alternatively, parasitic infections. Phenotypical alterations induced by IL-4 stimulation, include a shift in metabolism characterized by increased fatty acid oxidation (FAO), when compared to resting (MO) macrophages. I therefore aim to elucidate the role of  FAO in alternative macrophage activation, which will  contribute to the fundamental understanding of macrophage biology and metabolism.
 
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