Bioinformatician in Epigenetics

Max Planck Institute of Immunobiology and Epigenetics, Freiburg

Developmental and Evolutionary Biology & Genetics Immunobiology and Infection Biology & Medicine

Type of Job


Bioinformatician in Epigenetics

Job offer from October 01, 2018

A Bioinformatician in Epigenetics position will be available in the Jenuwein group at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany ( The Jenuwein group studies molecular mechanisms that establish and maintain heterochromatin in mammalian cells. There is a particular focus on the genome-wide regulation of repetitive element expression during mouse ES cell differentiation and in disease using a variety of experimental and next generation sequencing approaches. For these genome-wide analyses, we seek an experienced bioinformatician, with a strong background in data analysis and with previous exposure to chromatin biology and epigenetic control mechanisms.

The Max Planck Institute of Immunobiology and Epigenetics (MPI-IE) in Freiburg, Germany is an interdisciplinary research institution that conducts basic research in two key areas of modern biology: Immunobiology and Epigenetics. Central questions address the molecular basis of cell type identities, as they are regulated during immune cell differentiation, metabolic response and epigenetic chromatin adaptation.

This position is open immediately and initially funded for two years.

Your opportunities:

As an embedded bioinformatician, you will have the opportunity to contribute directly to multiple research projects, from experimental design to data analysis and interpretation. This position also offers additional possibilities for participating in the Collaborative Research Center “Medical Epigenetics” (MEDEP). You will also interact with a strong, interdisciplinary bioinformatics and deep sequencing team that provides access to a large Sequencing Facility (HiSeq3000, HiSeq2500, NextSeq500), as well as a high-performance Data Center with Petabyte-scale storage solutions.

Your tasks:

Responsibilities include the bioinformatics analysis of genome-wide datasets, such as ChIP-seq and RNA-seq, as well as transcription factor motif analysis and analysis of other next-generation sequencing-based experiments. A strong understanding of epigenetic mechanisms of gene regulation will also be necessary, in order to process, analyze, and interpret a variety of datasets, focusing particularly on repetitive DNA elements and chromatin modifying factors.

Your qualifications:

We are looking for a dedicated and motivated team player with strong communication skills and good command of the English language, who has a MSc or PhD degree in bioinformatics or biology with a clear computational component. The successful applicant will have a proven record in the analysis of genome-wide datasets and computational skills (Python, R) in a Linux environment. Knowledge of alignment programs (such as STAR), RepeatMasker, and data analysis and visualization tools in R will be necessary.

We offer:

Based within a region that connects Germany, France and Switzerland, our institute hosts a vibrant community of international researchers, state-of-the-art facilities, and modern office spaces. A childcare facility is directly attached to the institute. At the heart of the Black Forest, Freiburg offers a family-friendly atmosphere and excellent recreational possibilities for cultural and outdoor activities. Salaries will be based on previous experience according to the German pay scale for civil service (TVöD) including health insurance and other social benefits.

The Max Planck Society seeks to increase the number of women in areas where they are underrepresented and therefore explicitly encourages women to apply. Handicapped applicants with equal qualifications will be given preferential treatment.

Application deadline:

Have we sparked your interest? Please submit your complete application, including a 1 page motivation summary, CV and contact details of referees via our online application portal until October 31st 2018. For informal inquiries please

Max Planck Institute of Immunobiology and Epigenetics

Ms. Nadine Laule

Stübeweg 51

79108 Freiburg, Germany

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