Chromatin organization during development and disease: Marieke Oudelaar
Aus den Shownotes
In this episode of the Epigenetics Podcast, we caught up with Marieke Oudelaar from the Max Planck Institute of Immunobiology and Epigenetics to talk about her work on chromatin organization during development and disease.
Marieke Oudelaar and her team focus on on developing high-resolution Chromosome Conformation Capture (3C) based techniques, like low-input Capture-C, Tri-C, and Tiled-C. Those techniques are then used in combination with other genomic techniques, genetic perturbations, and computational approaches to investigate the 3D structure of chromatin in development and disease. The team focused on the interplay between genome organisation and regulation during mammalian differentiation, and how perturbations in these processes contribute to human disease, including cancer.
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Das Gespräch im Podcast wird in englischer Sprache geführt. Mehr Informationen über die Themen auf deutsch finden sich in der Webseite von Marieke Oudelaar.
