Publications of Erika Laine Pearce
All genres
Journal Article (89)
2024
Journal Article
15, 451 (2024)
Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment. Nature Communications
Journal Article
GIMAP5 deficiency reveals a mammalian ceramide-driven longevity assurance pathway. Nature Immunology (2024)
2023
Journal Article
26, 107719 (2023)
Metabolic and functional remodeling of colonic macrophages in response to high-fat diet-induced obesity. iScience
Journal Article
1523, pp. 38 - 50 (2023)
Immunometabolism at the crossroads of obesity and cancer-a Keystone Symposia report. Annals of the New York Academy of Sciences
Journal Article
24, pp. 501 - 515 (2023)
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development. Nature Immunology
Journal Article
24, pp. 516 - 530 (2023)
Phosphoinositide acyl chain saturation drives CD8+ effector T cell signaling and function. Nature Immunology 2022
Journal Article
14, eabj1270 (2022)
Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade. Science translational medicine: integrating medicine and science / American Association for the Advancement of Science
Journal Article
7, eadd3263 (2022)
Resident TH2 cells orchestrate adipose tissue remodeling at a site adjacent to infection. Science Immunology
Journal Article
185, pp. 3720 - 3738.e13 (2022)
mTOR-regulated mitochondrial metabolism limits mycobacterium-induced cytotoxicity. Cell
Journal Article
610, pp. 555 - 561 (2022)
An LKB1-mitochondria axis controls TH17 effector function. Nature
Journal Article
140, pp. 1167 - 1181 (2022)
Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation. Blood
Journal Article
13, 4674 (2022)
MYC sensitises cells to apoptosis by driving energetic demand. Nature Communications
Journal Article
34, pp. 747 - 760 (2022)
Intracellular infection and immune system cues rewire adipocytes to acquire immune function. Cell Metabolism
Journal Article
7, eabl7482 (2022)
A common framework of monocyte-derived macrophage activation. Science Immunology
Journal Article
29, pp. 131 - 148 (2022)
Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity. Cell Stem Cell 2021
Journal Article
141, pp. 2767 - 2774 (2021)
Research Techniques Made Simple: Profiling Cellular Energy Metabolism. The Journal of Investigative Dermatology: Official Journal of the Society for Investigative Dermatology and the European Society for Dermatological Research
Journal Article
54, pp. 2514 - 2530 (2021)
Plasmacytoid dendritic cell activation is dependent on coordinated expression of distinct amino acid transporters. Immunity
Journal Article
142, pp. 559 - 570 (2021)
Tofacitinib Suppresses IL-10/IL-10R Signaling and Modulates Host Defense Responses in Human Macrophages. The Journal of Investigative Dermatology: Official Journal of the Society for Investigative Dermatology and the European Society for Dermatological Research
Journal Article
184, pp. 4186 - 4202 (2021)
Polyamine metabolism is a central determinant of helper T cell lineage fidelity. Cell
Journal Article
184, pp. 4168 - 4185 (2021)
Metabolic modeling of single Th17 cells reveals regulators of autoimmunity. Cell
Journal Article
118, e2023752118 (2021)
Fever supports CD8+ effector T cell responses by promoting mitochondrial translation. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
12, 2133 (2021)
IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals. Nature Communications
Journal Article
591, pp. 471 - 476 (2021)
Sulfur sequestration promotes multicellularity during nutrient limitation. Nature
Journal Article
184, pp. 1135 - 1136 (2021)
How to make a better T cell: in vivo CRISPR screens have some answers. Cell
Journal Article
28, pp. 2194 - 2206 (2021)
Deletion of the mitochondria-shaping protein Opa1 during early thymocyte maturation impacts mature memory T cell metabolism. Cell Death and Differentiation 2020
Journal Article
11, 12 (2020)
Metabolic Dynamics of In Vitro CD8+ T Cell Activation. Metabolites
Journal Article
10, 21626 (2020)
MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells. Scientific Reports
Journal Article
32, pp. 981 - 995 (2020)
Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity. Cell Metabolism
Journal Article
12, p. eabb8969 (2020)
Metabolic reprogramming of donor T cells enhances graf-versus-leukemia effects in mice and humans. Science translational medicine: integrating medicine and science / American Association for the Advancement of Science
Journal Article
32, pp. 154 - 175 (2020)
Amino Assets: How Amino Acids Support Immunity. Cell Metabolism