Further information

Max Planck Special Guest Lecture Series

11791 1517410859

Alexander Stark - Decoding transcriptional regulation

  • Date: Mar 2, 2018
  • Time: 13:00 - 14:00
  • Speaker: Alexander Stark
  • Research Institute of Molecular Pathology (IMP), Vienna, Austria
  • Location: MPI-IE
  • Room: Main Lecture Hall
  • Host: Ritwick Sawarkar
Alexander Stark group leader at Research Institute of Molecular Pathology (IMP) in Vienna joins the Max Planck Special Guest Lecture Series at the MPI-IE. His research is focused on studying regulators of gene expression by combining systematic genome-wide experiments and computational analyses. On March 2nd, 2018 at 13 o'clock he will give a talk entitled “Decoding transcriptional regulation”. The talk will take place in the Main Lecture Hall of the Max Planck Institute of Immunobiology and Epigenetics, Freiburg. (http://www.ie-freiburg.mpg.de/events/11791/2342)

CV

Alexander Stark studied Biochemistry at the University of Tübingen and the University of North Carolina at Chapel Hill. For his PhD, he worked on structural bioinformatics and microRNA target prediction at the EMBL in Heidelberg and obtained his PhD in 2004. Afterwards, he moved to Cambridge, MA for a postdoctoral stay at the Broad Institute and CSAIL, MIT. There he focused on comparative and regulatory genomics in Drosophila. Since 2008, Alexander Stark is an independent group leader at the Research Institute of Molecular Pathology (IMP) in Vienna.

Research

His group combines genome-wide experiments and bioinformatics to understand the sequence basis of gene regulation: “The regulation of gene expression in response to developmental or environmental stimuli is a crucial mechanism in all organisms. We are fascinated by the question how transcription is regulated at the level of the two key types of regulatory genomic elements — enhancers and core-promoters — and the transcription factor and cofactor proteins that mediate transcription activation. We follow an interdisciplinary approach, using genome-wide functional assays, bioinformatics, biochemistry, and mass-spectrometry. We develop and employ highly-controllable reporter assays that provide a reliable functional readout for each of the questions we ask, while circumventing the many confounding issues that exist in complex gene regulatory systems in vivo. Our goal is to understand transcription and — ultimately — how transcriptional networks define cellular and developmental programs.”

source: lab page

 
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