Collaborations: Our Scientific Network

Local and national Collaborations

Besides the Max Planck Society, the German Federal Ministry for Education and Research (BMBF) and the Deutsche Forschungsgemeinschaft (DFG) are among the most important funding sources of the Max Planck Institute of Immunobiology and Epigenetics (MPI-IE).

Traditionally, the Max Planck Institute of Immunobiology and Epigenetics (MPI-IE) has long-standing interactions and cooperations with the University of Freiburg and its associated University Medical Center. One of the best examples of this successful cooperation is the joint University Department of Molecular Immunology that conducts research at the MPI-IE since 1996. With the establishment of the joint University Laboratory of Immunometabolism in 2015, the MPI-IE was able to continue and expand this partnership.

Furthermore, there are numerous research consortia that build on the collaborations between the MPI-IE and the University. For example, MPI-IE research groups are integrated in the cluster of excellence “BIOSS 2 - Centre for Biological Signalling Studies” funded by the Deutsche Forschungsgemeinschaft (DFG) and the Center of Chronic Immunodeficiency CCI, funded by the German Federal Ministry of Education and Research (BMBF).

CRC

Collaborative Research Centres (CRC, german: Sonderforschungsbereiche, SFB) are long-term university-based research institutions funded by the DFG, in which researchers work together within a multidisciplinary research programme. Within several CRCs based in Freiburg scientstist of the MPI-IE are in leading positions or working in close cooperation with their colleagues from University and the Medical Center.

Central goal of the CRC746 is the understanding of operations by multi-protein complexes and protein networks and how these operations endow any particular cell with its enormously precise and highly specific function. Research teams of the SFB746 analyze the molecular mechanisms behind the specificity of protein complexes and networks and their significance for cellular functions.

CRC746 "Functional specificity by coupling and modification of proteins"

Central goal of the CRC746 is the understanding of operations by multi-protein complexes and protein networks and how these operations endow any particular cell with its enormously precise and highly specific function. Research teams of the SFB746 analyze the molecular mechanisms behind the specificity of protein complexes and networks and their significance for cellular functions.

The working program of CRC850 is based on the emerging concept that most signalling pathways controlling normal embryonic development are aberrantly activated in human tumours. Therefore, the analysis of the function and regulation of these pathways during development will help to understand the mechanisms underlying pathological motility in cancer and vice versa.

CRC850 “Control of Cell Motility in Morphogenesis, Cancer Invasion and Metastasis”

The working program of CRC850 is based on the emerging concept that most signalling pathways controlling normal embryonic development are aberrantly activated in human tumours. Therefore, the analysis of the function and regulation of these pathways during development will help to understand the mechanisms underlying pathological motility in cancer and vice versa.
The CRC 992 »Medical Epigenetics«, MEDEP, provides a translational program for epigenetic research. Scientists from the University Freiburg Medical Centre, the University of Freiburg and the Max Planck Institute of Immunobiology and Epigenetics team up in a consortium that explores how findings in basic research on epigenetics can contribute in clincial application.

CRC992 “Medical Epigenetics - From basic mechanisms to clinical applications”

The CRC 992 »Medical Epigenetics«, MEDEP, provides a translational program for epigenetic research. Scientists from the University Freiburg Medical Centre, the University of Freiburg and the Max Planck Institute of Immunobiology and Epigenetics team up in a consortium that explores how findings in basic research on epigenetics can contribute in clincial application.
The CRC1140 KIDGEM proposes to analyze genes associated with kidney disease and translate gene function into an understanding of molecular renal physiology.

CRC1140 "Kidney Disease – From Genes to Mechanisms" (KIDGEM)

The CRC1140 KIDGEM proposes to analyze genes associated with kidney disease and translate gene function into an understanding of molecular renal physiology.
The CRC1160 is a research initiative of clinical and basic immunologists exploring the basis of diseases mediated by the immune system.

CRC1160 "Immune-mediated pathology as a consequence of impaired immune reactions" (IMPATH)”

The CRC1160 is a research initiative of clinical and basic immunologists exploring the basis of diseases mediated by the immune system.
The TRR130 examine how B cells are activated, how they differentiate and how plasma cells manage to produce high affinity antibodies for long periods of time. More precisely the reseearch consortium elucidates in detail how B cell responses are triggered, how self-reactive B cells are eliminated and how B cells learn to remember pathogens with which they have been challenged before.

TRR130 "B cells: Immunity and Autoimmunity"

The TRR130 examine how B cells are activated, how they differentiate and how plasma cells manage to produce high affinity antibodies for long periods of time. More precisely the reseearch consortium elucidates in detail how B cell responses are triggered, how self-reactive B cells are eliminated and how B cells learn to remember pathogens with which they have been challenged before.

Scientific Training & Education

Another major focus of the interactions between the MPI-IE and the University of Freiburg is the education of young scientists. Most group leaders including directors, who are usually affiliated with the faculties of biology or medicine, are involved in active teaching. All MPI-IE research groups also participate in the International Max-Planck Research School for Molecular and Cellular Biology (IMPRS-MCB). This joint international PhD Program of the MPI-IE and the University of Freiburg provides an outstanding scientific education in Molecular and Cellular Biology, Immunobiology and Epigenetics.

Deep – German Epigenome Program

Strong interactions exist also within the BMBF funded Project "DEEP - German Epigenome Program" (2012-2017), a collaboration of 14 research institutions and industry partners all over Germany. DEEP contributes to IHEC, the ‘International Human Epigenome Consortium’ by generating and interpreting up to 80 reference epigenomes of selected human cells and tissues. It focuses on the analysis of cells connected to complex diseases with high socio-economic impact: metabolic diseases such as steatosis and adipositas as well as inflammatory diseases of the joints and the intestine.

MPI-CC

In collaboration with the Max Planck Institute for Foreign and International Criminal Law (MPI-CC) in Freiburg, the MPI-IE organizes internal and external events.

 
loading content