Developmental Biology • Immunobiology
Research report (imported) 2016 - Max Planck Institute of Immunobiology and Epigenetics
Pebbles in the mosaic: Which cells shape our organs and where do they come from?
Max Planck Forschungsgruppe Quantitative Einzelzellbiologie
Every organ in our body is composed of a multitude of single cells. Key to understanding the function of an organ is the knowledge of all the distinct cell types with their respective function plus their developmental pathways, with a so-called stem cell as a common starting point. Innovative novel molecular biology methods now permit the simultaneous quantification of thousands of molecules across single cells. This reveals a fingerprint of a cell, permitting to discriminate cell types of different function and to infer developmental pathways.