Korrespondierender Autor

Developmental Biology • Immunobiology

Research report (imported) 2016 - Max Planck Institute of Immunobiology and Epigenetics

Pebbles in the mosaic: Which cells shape our organs and where do they come from?


Grün, Dominic


Max Planck Forschungsgruppe Quantitative Einzelzellbiologie



Every organ in our body is composed of a multitude of single cells. Key to understanding the function of an organ is the knowledge of all the distinct cell types with their respective function plus their developmental pathways, with a so-called stem cell as a common starting point. Innovative novel molecular biology methods now permit the simultaneous quantification of thousands of molecules across single cells. This reveals a fingerprint of a cell, permitting to discriminate cell types of different function and to infer developmental pathways.
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