Publications

Papa, C.; Rose, A.; Martin, H. N. G.; Useini, A.; Geier, F.; Liao, L.; Rodríguez-Aguilera, J. R.; Valina-Allo, P.; Hoffmann, A.; Tvardovskiy, A. et al.; Zulfqar, F.; Zimmerman, A.; Schicht, G.; Ott, F.; Körner, C.; Engelmann, B.; Rolle-Kampczyk, U.; von Bergen, M.; Meier, M.; Bartke, T.; Seehofer, D.; Klöting, N.; Matz-Soja, M.; Damm, G.; Boeckel, J.-N.; Büscher, J. M.; Blüher, M.; Laufs, U.; Bondareva, O.; Sträter, N.; Künze, G.; Heiker, J. T.; Sheikh, B. N.: Bempedoic acid directly binds and activates PPARα. Cell Metabolism 38 (2026)

Hilbert, J.; Topfstedt, F.; Matuschik, L.; Schmitt, L.; Panzeri, I.; Pospisilik, J. A.; Seifert, G.: Early-onset colorectal cancer is associated with metabolic disorders: a systematic review and meta-analysis. European Journal of Epidemiology (2026)

Carrizo, G. E.; Lin, P.; Lee, S. H.; Shenderov, K.; Blériot, C.; Cha, M.; Schimmelpfennig, L.; Shen, Z.; van Bakker, N. T.; Grzes, K. M. et al.; Kelly, B.; Safinia, N.; Schole, K. L.; Musa, Y.; Mittler, G.; Zen, Y.; Pearce, E. J.; Ginhoux, F.; Sanin, D. E.; Puleston, D. J.; Pearce, E. L.: The transition from monocyte to tissue-resident macrophage requires DHPS. Nature (2026)

Merck, P.-A.; Lösslein, A. K.; Neuber, J.; Schwer, S.; Jonas, W.; Pospisilik, J. A.; Hilgendorf, I.; Henneke, P.; Lohrmann, F.: Low-density lipoprotein cholesterol drives multinucleated giant cell formation in response to mycobacterium bovis Bacille Calmette-Guérin. Scientific Reports 16, 802 (2026)

Bowden, S.; Brislinger-Engelhardt, M. M.; Hansen, M.; Andricek, A.; Temporal-Plo, A.; Weber, D.; Hägele, S.; Lorenz, F.; Litwin, T.; Kreutz, C. et al.; Walentek, P.: Foxi1 regulates multipotent mucociliary progenitors and ionocyte specification through transcriptional and epigenetic mechanisms. PLOS Biology (2026)

Grün, S.; Rensing-Ehl, A.; Suske, T.; Wolter-Mess, J.; Gehrig, J.; Mann, J.; König, C.; Hauri, M.; Heeg, M.; Leahy, T. R. et al.; Genevieve, D.; Gaillard, J.-B.; Broly, M.; Bourdin, A.; Castro, C.; Seidel, L.; Bengsch, B.; Aichele, P.; Weißert, K.; Fernandez-Orth, J.; Schipperges, V.; Andrieux, G.; Boerries, M.; Cabezas-Wallscheid, N.; Erlacher, M.; Elling, R.; Speckmann, C.; Heller, L.; Schulte, B.; Lorenz, M.; Schwarz, K.; Moriggl, R.; Ehl, S.: Somatic STAT5B^N642H mutations shape variable immune landscapes resulting in heterogenous immune diseases. The Journal of Allergy and Clinical Immunology (2025)

Gu, T.; Gracheva, E.; Lee, M.; Leung, W.; Bieser, S.; Nielsen, A.; Smiley, A. T.; Vuong, N. N. T.; Walther, M.; Reuter, G. et al.; Elgin, S. C. R.; Arsham, A. M.: Heterochromatin-based silencing of a foreign tandem repeat in Drosophila melanogaster shows unusual biochemistry and temperature sensitivity. Genetics, iyaf275 (2025)

Rassner, M.; Müller, T. A.; Crossley, K. A.; Andrieux, G.; Schaberg, S.; Endres, C.; Jakob, L.; Poggio, T.; Köhler, N.; Kolter, J. et al.; Müller-Newen, G.; Schönberger, K.; Cabezas-Wallscheid, N.; Gonzalez-Menendez, I.; Quintanilla-Martinez, L.; Zwick, M.; Ashok, D.; Hartmann, T. N.; Groß, O.; Gorka, O.; Follo, M.; Illert, A. L.; Boerries, M.; Zeiser, R.; Duyster, J.: Oncostatin M induced by STAT5-activating oncogenes promotes disease progression in hematologic malignancies. Signal Transduction and Targeted Therapy 10, 400 (2025)

Taskiran, H.; Czeslik, E.; Stark, L.; Kläsener, K.; Schnalzger, T. E.; Ruland, J.; Reth, M.; Jellusova, J.: Mitochondrial calcium shapes B cell signaling and mitochondrial function. Frontiers in Immunology 16 (2025)

Maya, A. V.; Neuhaus, L.; Nogay, L.; Singh, A.; Heckmann, L.; Grass, I.; Büscher, J. M.; Kierdorf, K.; Classen, A.-K.: A JAK/STAT-Pdk1-S6K axis bypasses systemic growth restrictions to promote regeneration. Nature Communications 16, 10944 (2025)

Zhou, Y.; Jay, A.; Burget, N.; Friedrich, T.; Yoon, S.; Alsing, J.; Nir, G.; Grosschedl, R.; Vahedi, G.; Faryabi, R. B.: Lineage-determining transcription factors constrain cohesin to drive multi-enhancer oncogene regulation. Nature Cell Biology 28, pp. 149 - 165 (2025)

Morimoto, R.; Zhang, G.; Thomas, O. S.; Docker, M. F.; Yick, J. L.; Devloo-Delva, F.; Swann, J.; Diekhoff, D.; Boehm, T.: Lamprey FOXN1 rescues the block of thymic epithelial cell development in the mouse Foxn1-deficient thymic rudiment. Proceedings of the National Academy of Sciences of the United States of America 122, e2520664122 (2025)

Man, K.; da Silva, V. A. D.; Potemkin, N.; Gabriel, S. S.; Mason, T.; Elmzzahi, T.; Moreira, M. D. L.; Su, C.-H.; Mackay, L.; Beyer, M. D. et al.; Schröder, J.; Gasteiger, G.; Kallies, A.: Stem-like tissue-resident memory T cells control functional heterogeneity and reactivation of T cell memory in the intestine. Science Immunology 10, eadw1992 (2025)

Sica, V.; Smith, J. G.; Deryagin, O.; Andrés, E.; Lukesova, V.; Egg, M.; Cabezas-Wallscheid, N.; Benitah, S. A.; Serrano, A. L.; Perdiguero, E. et al.; Muñoz-Cánoves, P.: The central clock drives metabolic rhythms in muscle stem cells. Cell Reports 44, 116354 (2025)

Hohl, T.; Bönisch, U.; Manke, T.; Arrigoni, L.: Enhancing single-cell ATAC sequencing with formaldehyde fixation, cryopreservation, and multiplexing for flexible analysis. BMC Research Notes 18, 437 (2025)

Alfonso-Gonzalez, C.; Hilgers, V.: Elucidating the coordination of RNA processing using short-read and long-read RNA-sequencing methods. Nature Reviews Molecular Cell Biology (2025)

Wiese, M.; Rodrigues, C. P.; Akbas, M. E.; Sun, Y.; Holz, H.; Greene, J. A. M.; Tsang, T. H.; Bella, C.; Ganter, K.; Stehle, T. et al.; Shvedunova, M.; Akhtar, A.: KANSL3 directs transcriptional programs essential for hepatic metabolism and differentiation. Life science alliance 8, e202503238 (2025)

Zhou, Y.; Shvedunova, M.; Akhtar, A.: Protocol to isolate stress granules in HeLa cells using fluorescence-activated non-membrane condensate isolation. STAR Protocols 6, 103987 (2025)

Petry, P.; Oschwald, A.; Merkt, S.; Dinh, T.-L. J.; Andrieux, G.; Crisand, C.; Botterer, H.; Nent, E.; Paterson, N.; Havermans, M. et al.; Sankowski, R.; Schilling, O.; Boerries, M.; Amann, L.; Groß, O.; Schlitzer, A.; Prinz, M.; Lämmermann, T.; Kierdorf, K.: Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface. Developmental Cell 61, pp. 85 - 101 (2025)

Djeghloul, D.; Cheriyamkunnel, S.; Patel, B.; Kramer, H.; Montoya, A.; Brown, K. E.; Whilding, C.; Nesterova, T. B.; Wei, G.; Brockdorff, N. et al.; Grządzielewska, I.; Karayol, R.; Akhtar, A.; Merkenschlager, M.; Fisher, A. G.: Hbo1 and Msl complexes preserve differential compaction and H3K27me3 marking of active and inactive X chromosomes during mitosis. Nature Cell Biology 27, pp. 1482 - 1495 (2025)

Fuhrmann, T.; Shukeir, N.; Ching, R. W.; Erikson, G.; Dou, Y.; Sawitzki, Z.; Onishi-Seebacher, M.; Galan, C.; Jenuwein, T.: The isoflavone genistein selectively stimulates major satellite repeat transcription in mouse heterochromatin. Epigenetics & Chromatin 18, 58 (2025)

Frosch, M.; Shimizu, T.; Wogram, E.; Amann, L.; Gruber, L.; Groisman, A. I.; Fliegauf, M.; Schwabenland, M.; Chhatbar, C.; Zechel, S. et al.; Rosewich, H.; Gärtner, J.; Quintana, F. J.; Büscher, J. M.; Blank, T.; Binder, H.; Stadelmann, C.; Letzkus, J. J.; Hopf, C.; Masuda, T.; Knobeloch, K.-P.; Prinz, M.: Microglia-neuron crosstalk through Hex-GM2-MGL2 maintains brain homeostasis. Nature 646, pp. 913 - 924 (2025)

Knipper, J. A.; Campbell, S. M.; Allen, J. E.; Taylor, M. D.: PD-L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA-3 Expression During Filarial Nematode Infection. European Journal of Immunology 55 (2025)

Das, S.; Fontenla-Iglesias, F.; Hirano, M.; Morimoto, R.; Au-Yeung, B. B.; Wang, Y.; Li, W.; Boehm, T.; Rast, J. P.; Cooper, M. D.: Variable lymphocyte receptor F is generated via somatic diversification and expressed by lamprey T-like cells. Nature Communications 16, 6503 (2025)

Lalioti, M.-E.; Romero-Mulero, M. C.; Karabacz, N.; Mess, J.; Demollin, H.; Rettkowski, J.; Schuldes, K.; Mitterer, M.; Wadle, C.; Shoumariyeh, K. et al.; Egg, M.; Alfonso-Gonzalez, C.; Jäcklein, K.; Schönberger, K.; Karantzelis, N.; Reisig, G.; Aktories, P.; Mayer, I. M.; Tsoukala, I.; Schäffer, A.; Tirado-Gonzalez, I.; Dugourd, A.; Braun, L. M.; Silva-Rego, B.; Jones, M.-J.; Kierdorf, K.; Saez-Rodriguez, J.; Reising, K.; Walter, S. G.; Medyouf, H.; Hilgers, V.; Ghiaur, G.; Zeiser, R.; Karpova, D.; Renders, S.; Gravius, S.; Büscher, J. M.; Cabezas-Wallscheid, N.: Differentiation, ageing and leukaemia alter the metabolic profile of human bone marrow haematopoietic stem and progenitor cells. Nature Cell Biology 27, pp. 1367 - 1380 (2025)

Ardura-Fabregat, A.; Bosch, L. F. P.; Wogram, E.; Mossad, O.; Sankowski, R.; Aktories, P.; Kieger, L.; Cook, J.; Hasavci, D.; Ulupinar, H. et al.; Brock, D.; Wang, F.; Iovino, N.; Wald, S.; Preissl, S.; Yilmaz, B.; Schnepf, D.; Macpherson, A. J.; Blank, T.; Kierdorf, K.; Prinz, M.: Response of spatially defined microglia states with distinct chromatin accessibility in a mouse model of Alzheimer's disease. Nature Neuroscience 28, pp. 1688 - 1703 (2025)

Ching, R. W.; Świst-Rosowska, K. M.; Erikson, G.; Koschorz, B.; Engist, B.; Jenuwein, T.: Forced expression of MSR repeat transcripts above a threshold limit breaks heterochromatin organisation. Nature Communications 16, 6420 (2025)

Glaser, J.; Cova, G.; Fauler, B.; Prada-Medina, C. A.; Stanislas, V.; Phan, M. H. Q.; Schöpflin, R.; Aktas, Y.; Franke, M.; Andrey, G. et al.; Bartzoka, N.; Paliou, C.; Laupert, V.; Chan, W.-L.; Wittler, L.; Mielke, T.; Mundlos, S.: Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes. Nature Genetics (2025)

Chatterjee, S.; Rückert, T.; Martin, I.; Michaeli, E.; Büscher, J. M.; Apostolova, P.; Erny, D.; Lalioti, M.-E.; Biavasco, F.; Hartmann, A. et al.; Runge, S.; Braun, L. M.; Talvard-Balland, N.; Adams, R. C.; Schmitt-Graeff, A.; Cook, J.; Wenger, V.; Athanassopoulos, D.; Hasavci, D.; Vallejo-Janeta, A. P.; Blank, T.; Schaible, P.; Vinnakota, J. M.; Zähringer, A.; Ganal-Vonarburg, S. C.; Melchinger, W.; Pfeifer, D.; Köhler, N.; Rosshart, S. P.; Michonneau, D.; Socié, G.; Andrieux, G.; Cabezas-Wallscheid, N.; Boerries, M.; Prinz, M.; Zeiser, R.: Gut microbiota-derived TMAVA is a modulator of acute CNS-GVHD. Journal of experimental medicine: JEM 222, e20242180 (2025)

Argaw-Denboba, A.: The gut microbiome–germline axis: Does a prospective father’s gut microbiota matter? Science 389, pp. 38-A - 38-B (2025)