Publications

Journal Article (1210)

  1. 2020
    Journal Article
    van Teijlingen Bakker, N.; Pearce, E. J.: Cell-intrinsic metabolic regulation of mononuclear activation: Findings from the tip of the iceberg. Immunological Reviews 295, pp. 54 - 67 (2020)
  2. Journal Article
    Mereu, E.; Lafzi, A.; Moutinho, C.; Ziegenhain, C.; McCarthy, D. J.; Álvarez-Varela, A.; Batlle, E.; Sagar, S.; Grün, D.; Lau, J. K. et al.; Boutet, S. C.; Sanada, C.; Ooi, A.; Jones, R. C.; Kaihara, K.; Brampton, C.; Talaga, Y.; Sasagawa, Y.; Tanaka, K.; Hayashi, T.; Braeuning, C.; Fischer, C.; Sauer, S.; Trefzer, T.; Conrad, C.; Adiconis, X.; Nguyen, L. T.; Regev, A.; Levin, J. Z.; Parekh, S.; Janjic, A.; Wange, L. E.; Bagnoli, J. W.; Enard, W.; Gut, M.; Sandberg, R.; Nikaido, I.; Gut, I.; Stegle, O.; Heyn, H.: Benchmarking single-cell RNA-sequencing protocols for cell atlas projects. Nature Biotechnology (2020)
  3. Journal Article
    Sommerkamp, P.; Altamura, S.; Renders, S.; Narr, A.; Ladel, L.; Zeisberger, P.; Eiben, P. L.; Fawaz, M.; Rieger, M. A.; Cabezas-Wallscheid, N. et al.; Trumpp, A.: Differential Alternative Polyadenylation Landscapes Mediate Hematopoietic Stem Cell Activation and Regulate Glutamine Metabolism. Cell Stem Cell (2020)
  4. Journal Article
    Puleston, D.; Pearce, E. L.: Appetite for Arginine: Metabolic Control of Macrophage Hunger. Cell Metabolism 31, pp. 441 - 442 (2020)
  5. Journal Article
    Sagar , S.; Grün, D.: Deciphering Cell Fate Decision by Integrated Single-Cell Sequencing Analysis. Annual Review of Biomedical Data Science 3, pp. 1 - 22 (2020)
  6. Journal Article
    Dereka, M.; Herman, J. S.; Cauchy, P.; Ramamoorthy, S.; Lupar, E.; Grün, D.; Grosschedl, R.: EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential. Nature 21, pp. 261 - 273 (2020)
  7. Journal Article
    Walther , M.; Schrahn, S.; Krauss, V.; Lein, S.; Kessler, J.; Jenuwein, T.; Reuter, G.: Heterochromatin formation in Drosophila requires genome-weide histone deacetylation in cleavage chromatin before mid-blastula transition in early embryongenesis. Chromosoma: Biology of the Nucleus 129, pp. 83 - 98 (2020)
  8. Journal Article
    Ilik, I. A.; Aktas, T.; Maticzka, D.; Backofen, R.; Akhtar, A.: FLASH: ultra-fast protocol to identify RNA-protein interactions in cells. Nucelic Acids Research 48, p. e15 (2020)
  9. Journal Article
    Zenke, S.; Palm, M. M.; Braun, J.; Gavrilov, A.; Meiser, P.; Böttcher, J. P.; Beyersdorf, N.; Ehl, S.; Gerard, A.; Lämmermann, T. et al.; Schumacher, T. N.; Beltman, J. B.; Rohr, J. C.: Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics. Immunity 52, pp. 313 - 327 (2020)
  10. Journal Article
    Angiari, S.; Runtsch, M. C.; Sutton, C. E.; Palsson-McDermott, E. M.; Kelly, B.; Rana, N.; Kane, H.; Papadopoulou, G.; Pearce, E. L.; Mills, K. H.G. et al.; O'Neill, L. A.J.: Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+-T Cell Pathogenicity and Suppresses Autoimmunity. Cell Metabolism 31, pp. 391 - 405 (2020)
  11. Journal Article
    Field, C.; Baixauli Celda, F.; Puleston, D.; Kyle, R.; Alana, C.; Sanin, P. D. E.; Hippen, K. L.; Loschi, M.; Thangavelu, G.; Corrado, M. et al.; Edwards-Hicks, J.; Grzes, K.; Pearce, E. J.; Blazar, B. R.; Pearce, E. L.: Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function. Cell Metabolism 31, pp. 422 - 437 (2020)
  12. Journal Article
    Ward, C.; Cauchy, P.; Garcia, P.; Frampton, J.; Esteban, M. A.; Volpe, G.: High WBP5 expression correlates with elevation of HOX genes levels and is associated with inferior survival in patients with acute myeloid leukaemia. Scientific Reports 10, p. 3505 (2020)
  13. Journal Article
    Grün, D.: Revealing dynamics of gene expression variability in cell state space. Nature methods, pp. 45 - 49 (2020)
  14. 2019
    Journal Article
    Sankowski, R.; Böttcher, C.; Masuda, T.; Geirsdottir, L.; Sagar, S.; Sindram, E.; Seredenina, T.; Muhs, A.; Scheiwe, C.; Shah, M. J. et al.; Heiland, D. H.; Schnell, O.; Grün, D.; Priller, J.; Prinz, M.: Mapping microglia states in teh human brain through the integration of high-dimensional techniques. Nature Neuroscience 22, pp. 2098 - 2110 (2019)
  15. Journal Article
    Sheikh, B. N.; Bondareva, O.; Guhathakurta, S.; Tsang, T. H.; Sikora, K.; Aizarani, N.; Sagar, S.; Holz, H.; Grün, D.; Hein, L. et al.; Akhtar, A.: Systematic Identification of Cell-Cell Communication Networks in the Developing Brain. iScience 21, pp. 273 - 287 (2019)
  16. Journal Article
    Grün, D.: Revealing dynamics of gene expression variability in cell state space. Nature methods (2019)
  17. Journal Article
    Lawir, D.-F.; Hess, I.; Sikora, K.; Iwanami, N.; Siamishi, I.; Schorpp, M.; Boehm, T.: Evolutionary transitionf rom degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development. Proceedings of the National Academy of Sciences of the United States of America (2019)
  18. Journal Article
    Antonova, A.; Hummel, B.; Khavaran, A.; Redhaber, D. M.; Aprile-Garcia, F.; Rawat, P.; Gundel, K.; Schneck, M.; Hansen, E. C.; Mitschke, J. et al.; Mittler, G.; Miething, C.; Sawarkar, R.: Heat-Shock Protein 90 Controls the Expression of Cell-Cycle Genes by Stabilizing Metazoan-Specific Host-Cell Factor HCFC1. Cell Reports 29, pp. 1645 - 1659 (2019)
  19. Journal Article
    Saçma, M.; Pospiech, J.; Bogeska, R.; de Back, W.; Mallm, J.-P.; Sakk, V.; Soller, K.; Marka, G.; Vollmer, A.; Karns, R. et al.; Cabezas-Wallscheid, N.; Trumpp, A.; Méndez-Ferrer, S.; Milsom, M. D.; Mulaw, M. A.; &, H. G.; Florian, M. C.: Haematopoietic stem cells in perisinusoidal niches are protected from ageing. Nature Cell Biology 21, pp. 1309 - 1320 (2019)
  20. Journal Article
    Karoutas, A.; Szymanski, W.; Rausch, T.; Guhathakurta, S.; Rog-Zielinska, E. A.; Peyronnet, R.; Seyfferth, J.; Chen, H.-R.; de Leeuw, R.; Herquel, B. et al.; Kimura, H.; Mittler, G.; Kohl, P.; Medalia, O.; Korbel, J. O.; Akhtar, A.: The NSL complex maintains nuclear architecture stability via lamin A/C acetylation. Nature Cell Biology 21, pp. 1248 - 1260 (2019)
  21. Journal Article
    O'Sullivan, D.: The metabolic spectrum of memory T cells. Immunology and Cell Biology 97, pp. 636 - 646 (2019)
  22. Journal Article
    Bhardwaj, V.; Semplicio, G.; Erdogdu, N. U.; Manke, T.; Akhtar, A.: MapCap allows high-resolution detection and differential expression analysis of transcription start sites. Nature Communications 10, p. 3219 (2019)
  23. Journal Article
    Aizarani, N.; Saviano, A.; Sagar, S.; Mailly , L.; Durand, S.; Herman, J. S.; Pessaux, P.; Baumert , T. F.; Grün, D.: A human liver cell atlas reveals heterogeneity and epithelial progenitors. Nature 572, pp. 199 - 204 (2019)
  24. Journal Article
    Uderhardt, S.; Martins, A. J.; Tsang, J. S.; Lämmermann, T.; Germain, R. N.: Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage. Cell 177, pp. 541 - 555 (2019)
  25. Journal Article
    Klein-Geltink, R.; Pearce , E. L.: The Importance of methionine metabolism. eLife 8, p. e47221 (2019)
  26. Journal Article
    O'Sullivan, D.; Sanin, P. D. E.; Pearce, E. J.; Pearce, E. L.: Metabolic interventions in the immune response to cancer. Nature Reviews Immunology 19, pp. 324 - 334 (2019)
  27. Journal Article
    Cameron, A. M.; Castoldi, A.; Sanin, D. E.; Flachsmann, L. J.; Field, C. S.; Puleston, D. J.; Kyle, R. L.; Patterson, A.; Hassler, F.; Buescher, J. M. et al.; Kelly, B.; Pearce, E. L.; Pearce, E. J.: Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species-mediated DNA damage. Nature Immunology 20, pp. 420 - 432 (2019)
  28. Journal Article
    Mateo, V.; Baixauli Celda, F.; Pearce, E. L.: Potassium shapes antitumor immunity. Science 363, pp. 1395 - 1396 (2019)
  29. Journal Article
    Lam, K.-C.; Chung, H.-R.; Semplicio, G.; Iyer, S. S.; Gaub, A.; Bhardwaj, V.; Holz, H.; Georgiev, P.; Akhtar, A.: The NSL complex-mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise. Genes and Development 33, pp. 453 - 465 (2019)
  30. Journal Article
    Wilhelm, I.; Levit-Zerdoun, E.; Jakob, J.; Villringer, S.; Frensch, M.; Übelhart, R.; Landi, A.; Müller, P.; Imberty, A.; Thuenauer, R. et al.; Claudinon, J.; Jumaa, H.; Reth, M.; Eibel, H.; Hobeika, E.; Römer, W.: Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins. Science Signaling 12, p. eaao7194 (2019)
 
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