Seminars & Events

Dr. Hannah Uckelmann is Max-Eder junior research group leader at University Hospital Goethe Universität Frankfurt, Germany. Her lab focuses on studying the epigenetic regulation of self-renewal programs during cancer development and the discovery of new therapeutics. Hannah discovered an unexpected role of mutant NPM1 on chromatin representing the molecular basis for the effectiveness of targeted epigenetic therapies in NPM1 mutant AML. NPM1c cooperates with other chromatin factors to change the chromatin landscape and enhance transcriptional output at its target sites. She and her team continued investigating NPM1c-driven leukemogenesis with focus on novel therapeutic therapies in NPM1 mutant AML. [more]

Prof. Gad Asher heads a research group at the Weizmann Institute in Israel. The lab studies circadian biology and metabolism (e.g., exercise and hypoxia) by combining molecular, physiological, behavioral, and computational approaches. The overarching goal is to uncover molecular mechanism within the core clock circuitry in respect to cellular metabolism and identify metabolic cycles in mammals. Gad visits the Institute in November and will present a talk on “The cross talk between circadian clocks and oxygen biology”. [more]