Lena Pernas - Mitochondria-Microbe Conflict

“The overarching goal of the Pernas lab is to understand how human metabolism influences the progression of infectious disease at the cellular and organismal level. A key focus of our studies, therefore, is elucidating the inputs that rewire metabolism during infection. Ageing has profound effects on metabolism and the response to microbial infection and therefore provides an optimal angle to begin dissecting these inputs. We use the genetically tractable human parasite Toxoplasma gondii as a model pathogen and combine advanced live-cell imaging, protein and metabolite profiling, and genomic screens with molecular and biochemical approaches.”

source: https://www.ageing-grad-school.de/phd/host-lab-proposals/dr-lena-pernas/

twitter: @lenapernas