Publications of H. Jumaa

Hobeika, E.; Thiemann, S.; Storch, B.; Jumaa, H.; Nielsen, P.J.; Pelanda, R.; Reth, M.: Testing gene function early in the B cell lineage in mb 1-cre mice. Proceedings of the National Academy of Sciences of the United States of America 103, pp. 13789 - 13794 (2006)

Kersseboom, R.; Ta, V. B. T.; Zijlstra, A. J. E.; Middendorp, S.; Jumaa, H.; van Loo, P. F.; Hendriks, R. W.: Bruton's Tyrosine Kinase and SLP-65 Regulate Pre-B Cell Differentiation and the Induction of Ig Light Chain Gene Rearrangement. The Journal of Immunology 176, pp. 4543 - 4552 (2006)

Klein, F.; Feldhahn, N.; Herzog, S.; Sprangers, M.; Mooster, J. L.; Jumaa, H.; Müschen, M.: BCR-ABL1 induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cells. Oncogene 25, pp. 1118 - 1124 (2006)

Sprangers, M.; Feldhahn, N.; Herzog, S.; Hansmann, M.-L.; Reppel, M.; Hescheler, J.; Jumaa, H.; Siebert, R.; Müschen, M.: The SRC family kinase LYN redirects B cell receptor signaling in human SLP65-deficient B cell lymphoma cells. Oncogene 25, pp. 5056 - 5062 (2006)

Sprangers, M.; Feldhahn, N.; Liedtke, S.; Jumaa, H.; Müschen, M.: SLP65 deficiency results in perpetual V(D)J recombinase activity in pre-B-lymphoblastic leukemia and B-cell lymphoma cells. Oncogene 25, pp. 5180 - 5186 (2006)

Feldhahn, N.; Rio, P.; Soh, B. N. B.; Liedtke, S.; Sprangers, M.; Klein, F.; Wernet, P.; Jumaa, H.; Hofmann, W.-K.; Hanenberg, H. et al.; Rowley, J. D.; Müschen, M.: Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells. Proceedings of the National Academy of Sciences 102, pp. 13266 - 13271 (2005)

Feldhahn, N.; Klein, F.; Mooster, J. L.; Hadweh, P.; Sprangers, M.; Wartenberg, M.; Bekhite, M. M.; Hofmann, W.-K.; Herzog, S.; Jumaa, H. et al.; Rowley, J. D.; Müschen, M.: Mimicry of a constitutively active pre-B cell receptor in acute lymphoblastic leukemia cells. The Journal of Experimental Medicine 201, pp. 1837 - 1852 (2005)

Köhler, F.; Storch, B.; Kulathu, Y.; Herzog, S.; Kuppig, S.; Reth, M.; Jumaa, H.: A leucine zipper in the N terminus confers membrane association to SLP-65. Nature Immunology 6, pp. 204 - 210 (2005)

Jumaa, H.; Hendriks, R. W.; Reth, M.: B Cell Signaling and Tumorigenesis. Annural Reviews of Immunology 23, pp. 415 - 445 (2005)

Middendorp, S.; Zijlstra, A. J. E.; Kersseboom, R.; Dingjan, G. M.; Jumaa, H.; Hendriks, R. W.: Tumor suppressor function of Bruton tyrosine kinase is independent of its catalytic activity. Blood 105, pp. 259 - 265 (2005)

Parker, M. J.; Licence, S.; Erlandsson, L.; Galler, G. R.; Chakalova, L.; Osborne, C. S.; Morgan, G.; Fraser, P.; Jumaa, H.; Winkler, T. H. et al.; Mårtensson, I.-L.: The pre-B-cell receptor induces silencing of VpreB and λ5 transcription. The EMBO Journal 24, pp. 3895 - 3905 (2005)

Nichols, K. E.; Haines, K.; Myung, P. S.; Newbrough, S.; Myers, E.; Jumaa, H.; Shedlock, D. J.; Shen, H.; Koretzky, G. A.: Macrophage activation and Fcγ receptor-mediated signaling do not require expression of the SLP-76 and SLP-65 adaptors. Journal of Leukocyte Biology 75, pp. 541 - 552 (2004)

Su, Y.-w.; Herzog, S.; Lotz, M.; Feldhahn, N.; Müschen, M.; Jumaa, H.: The molecular requirements for LAT-mediated differentiation and the role of LAT in limiting pre-B cell expansion. European Journal of Immunology 34, pp. 3614 - 3622 (2004)

Gerlach, J.; Ghosh, S.; Jumaa, H.; Reth, M.; Wienands, J.; Chan, A. C.; Nitschke, L.: B cell defects in SLP65/BLNK-deficient mice can be partially corrected by the absence of CD22, an inhibitory coreceptor for BCR signaling. European Journal of Immunology 33 (12), pp. 3418 - 3426 (2003)

Su, Y.-W.; Flemming, A.; Wossning, T.; Hobeika, E.; Reth, M.; Jumaa, H.: Identification of a Pre-BCR Lacking Surrogate Light Chain. Journal of Experimental Medicine 198 (11), pp. 1699 - 1706 (2003)

Su, Y.-W.; Jumaa, H.: LAT Links the Pre-BCR to Calcium Signaling. Immunity 19 (2), pp. 295 - 305 (2003)

Kersseboom, R.; Middendorp, S.; Dingjan, G. M.; Dahlenborg, K.; Reth, M.; Jumaa, H.; Hendriks, R. W.: Bruton's Tyrosine Kinase Cooperates with the B Cell Linker Protein SLP-65 as a Tumor Suppressor in Pre-B Cells. Journal of Experimental Medicine 198 (1), pp. 91 - 98 (2003)

Jumaa, H.; Bossaller, L.; Portugal, K.; Storch, B.; Lotz, M.; Flemming, A.; Schrappe, M.; Postila, V.; Riikonen, P.; Pelkonen, J. et al.; Niemeyer, C. M.; Reth, M.: Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia. Nature 423 (6938), pp. 452 - 456 (2003)

Flemming, A.; Brummer, T.; Reth, M.; Jumaa, H.: The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion. Nature Immunology 4 (1), pp. 38 - 43 (2003)

Jumaa, H.: Control of B cell development by signaling proteins. Habilitation, Albert-Ludwigs-Universität, Freiburg (2006)