Max Planck Institute of Immunobiology and Epigenetics

Publications of Rudolf Grosschedl

All genres

Journal Article (66)

2012

Journal Article

Skokowa, J.; Klimiankou, M.; Klimenkova, O.; Lan, D.; Gupta, K.; Hussein, K.; Carrizosa, E.; Kusnetsova, I.; Li, Z.; Sustmann, C. et al.; Ganser, A.; Zeidler, C.; Kreipe, H.-H.; Burkhardt, J.; Grosschedl, R.; Welte, K.: Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis. Nature Medicine 18, pp. 1550 - 1559 (2012)

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Wei, J.; Shi, Y.; Zheng, L.; Zhou, B.; Inose, H.; Wang, J.; Guo, X. E.; Grosschedl, R.; Karsenty, G.: miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. The Journal of Cell Biology: JCB 197, pp. 509 - 521 (2012)

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Györy, I.; Boller, S.; Nechanitzky, R.; Mandel, E.; Pott, S.; Liu, E.; Grosschedl, R.: Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells. Genes and Development 26, pp. 668 - 682 (2012)

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2011

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Zhang, J.; Tu, Q.; Grosschedl, R.; Kim, M. S.; Griffin, T.; Drissi, H.; Yang, P.; Chen, J.: Roles of SATB2 in osteogenic differentiation and bone regeneration. Tissue Engineering 17, pp. 1767 - 1776 (2011)

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2010

Journal Article

Flach, H.; Rosenbaum, M.; Duchniewicz, M.; Kim, S.; Zhang, S. L.; Cahalan, M. D.; Mittler, G.; Grosschedl, R.: Mzb1 Protein Regulates Calcium Homeostasis, Antibody Secretion, and Integrin Activation in Innate-like B Cells. Immunity 33, pp. 723 - 735 (2010)

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Treiber, N.; Treiber, T.; Zocher, G.; Grosschedl, R.: Structure of an Ebf1: DNA complex reveals unusual DNA recognition and structural homology with Rel proteins. Genes and Development 24, pp. 2270 - 2275 (2010)

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Kieslinger, M.; Hiechinger, S.; Dobreva, G.; Consalez, G. G.; Grosschedl, R.: Early B Cell Factor 2 Regulates Hematopoietic Stem Cell Homeostasis in a Cell-Nonautonomous Manner. Cell Stem Cell 7, pp. 496 - 507 (2010)

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Journal Article

Treiber, T.; Mandel, E. M.; Pott, S.; Györy, I.; Firner, S.; Liu, E. T.; Grosschedl, R.: Early B Cell Factor 1 Regulates B Cell Gene Networks by Activation, Repression and Transcription - Independent Poising of Chromatin. Immunity 32, pp. 714 - 725 (2010)

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Mandel, E. M.; Grosschedl, R.: Transcription control of early B cell differentiation. Current Opinion in Immunology 22, pp. 161 - 167 (2010)

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Sen, R.; Grosschedl, R.: Memories of lost enhancers. Genes and Development 2, pp. 973 - 979 (2010)

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2009

Journal Article

Savarese, F.; Dávila, A.; Nechanitzky, R.; De la Rosa-Velazquez, I. A.; Pereira, C. F.; Engelke, R.; Takahashi, K.; Jenuwein, T.; Kohwi-Shigematsue, T.; Fisher, A. et al.; Grosschedl, R.: Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression. Genes and Development 23, pp. 2625 - 2638 (2009)

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2008

Journal Article

Sustmann, C.; Flach, H.; Ebert, H.; Eastman, Q.; Grosschedl, R.: Cell-Type-Specific Function of BCL9 Involves a Transcriptional Activation Domain that Synergizes with β-Catenin. Molecular and Cellular Biology (Washington, DC) 28, pp. 3526 - 3537 (2008)

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Dawlaty, M. M.; Malureanu, L.; Jeganathan, K. B.; Kao, E.; Sustmann, C.; Tahk, S.; Shuai, K.; Grosschedl, R.; van Deursen, J. M.: Resolution of Sister Centromeres Requires RanBP2-Mediated SUMOylation of Topoisomerase IIα. Cell 133, pp. 103 - 115 (2008)

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Nielsen, P.; Grosschedl, R.: Multitasking of Interferon Regulatory Factor-4 in Early B Cells. Immunity 28, pp. 295 - 297 (2008)

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Alcamo, E. A.; Chirivella, L.; Dautzenberg, M.; Dobreva, G.; Farinas, I.; Grosschedl, R.; McConnell, S. K.: Satb2 Regulates Callosal Projection Neuron Identity in the Developing Cerebral Cortex. Neuron 57, pp. 364 - 377 (2008)

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Pongubala, J. M. R.; Northrup, D. L.; Lancki, D. W.; Medina, K. L.; Treiber, T.; Bertolino, E.; Thomas, M.; Grosschedl, R.; Allman, D.; Singh, H.: Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nature Immunology 9, pp. 203 - 215 (2008)

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2007

Journal Article

Tolkunova, E.; Malashicheva, A.; Parfenov, V. N.; Sustmann, C.; Grosschedl, R.; Tomilin, A.: PIAS Proteins as Repressors of Oct4 Function. Journal of Molecular Biology (London) 374, pp. 1200 - 1212 (2007)

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Schneider, R.; Grosschedl, R.: Dynamics and interplay of nuclear architecture, genome organization, and gene expression. Genes and Development 21, pp. 3027 - 3043 (2007)

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Iwatsuki, K.; Liu, H.-X.; Gründer, A.; Singer, M.; Lane, T. F.; Grosschedl, R.; Mistretta, C.; Margolskee, R. F.: Wnt signaling interacts with Shh to regulate taste papilla development. Proceedings of the National Academy of Sciences of the United States of America 104, pp. 2253 - 2258 (2007)

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Journal Article

Roessler, S.; Györy, I.; Imhof, S.; Spivakov, M.; Williams, R. R.; Busslinger, M.; Fischer, A. G.; Grosschedl, R.: Distinct Promoters Mediate the Regulation of Ebf1 Gene Expression by Interleukin-7 and Pax5. Molecular and Cellular Biology (Washington, DC) 27, pp. 579 - 594 (2007)

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2006

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Skokowa, J.; Cario, G.; Uenalan, M.; Schambach, A.; Germeshausen, M.; Battmer, K.; Zeidler, C.; Lehmann, U.; Eder, M.; Baum, C. et al.; Grosschedl, R.; Stanulla, M.; Scherr, M.; Welte, K.: LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia. Nature Medicine 12, pp. 1191 - 1197 (2006)

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Savarese, F.; Grosschedl, R.: FOXtrot and RAGtime in B cells. Nature Immunology 7, pp. 793 - 794 (2006)

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Savarese, F.; Grosschedl, R.: Blurring cis and trans in Gene Regulation. Cell 126, pp. 248 - 250 (2006)

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Boras-Granic, K.; Chang, H.; Grosschedl, R.; Hamel, P. A.: Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland. Developmental Biology 295, pp. 219 - 231 (2006)

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Dobreva, G.; Chahrour, M.; Dautzenberg, M.; Chirivella, L.; Kanzler, B.; Farinas, I.; Karsenty, G.; Grosschedl, R.: SATB2 Is a Multifunctional Determinant of Craniofacial Patterning and Osteoblast Differentiation. Cell 125, pp. 971 - 986 (2006)

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Olson, L. E.; Tollkuhn, J.; Scafoglio, C.; Krones, A.; Zhang, J.; Ohgi, K. A.; Wu, W.; Taketo, M.; Kemler, R.; Grosschedl, R. et al.; Rose, D.; Li, X.: Homeodomain-Mediated β-Catenin-Dependent Switching Events Dictate Cell-Lineage Determination. Cell 125, pp. 593 - 605 (2006)

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Roessler, S.; Grosschedl, R.: Role of transcription factors in commitment and differentiation of early B lymphoid cells. Seminars in Immunology 18, pp. 12 - 19 (2006)

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Boras-Granic, K.; Grosschedl, R.; Hamel, P. A.: Genetic interaction between Lef1 and Alx4 is required for early embryonic development. International Journal of Developmental Biology 50, pp. 601 - 610 (2006)

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2005

Journal Article

Kieslinger, M.; Folberth, S.; Dobreva, G.; Dorn, T.; Croci, L.; Erben, R.; Consalez, G. G.; Grosschedl, R.: EBF2 Regulates Osteoblast-Dependent Differentiation of Osteoclasts. Developmental Cell 9, pp. 757 - 767 (2005)

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Sasaki, T.; Ito, Y.; Xu, X.; Han, J.; Bringas, P.; Maeda, T.; Harold, S. C.; Grosschedl, R.; Chai, Y.: LEF1 is a critical epithelial survival factor during tooth morphogenesis. Developmental Biology 278, pp. 130 - 143 (2005)

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