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Journal Article (34)

  1. 2020
    Journal Article
    Walther , M.; Schrahn, S.; Krauss, V.; Lein, S.; Kessler, J.; Jenuwein, T.; Reuter, G.: Heterochromatin formation in Drosophila requires genome-weide histone deacetylation in cleavage chromatin before mid-blastula transition in early embryongenesis. Chromosoma: Biology of the Nucleus 129, pp. 83 - 98 (2020)
  2. Journal Article
    Walther, M.; Schrahn, S.; Krauss, V.; Lein, S.; Kessler, J.; Jenuwein, T.; Reuter, G.: Heterochromatin formation in Drosophila requires genome-wide histone deacetylation in cleavage chromatin before mid-blastula transition in early embryogenesis. Chromosoma: Biology of the Nucleus 129, pp. 83 - 98 (2020)
  3. 2019
    Journal Article
    Nicetto, D.; Donahue, G.; Jain, T.; Peng, T.; Sidoli, S.; Sheng, L.; Montavon, T.; Becker, J. S.; Grindheim, J. M.; Blahnik, K. et al.; Garcia, B. A.; Tan, K.; Bonasio, R.; Jenuwein, T.; Zaret, K. S.: H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science 363, pp. 294 - 297 (2019)
  4. Journal Article
    Qui, J.; Mateo, V.; Sanin, D. E.; Buck, M. D.; O'Sullivan, D.; Ching, R.; Matsushita, M.; Grzes, K.; Winkler, F.; Chang, C.-H. et al.; Curtis, J.; Kyle, R.; Van Teijlingen, N.; Corrado, M.; Haessler, F.; Alfei, F.; Edwards-Hicks, J.; Maggi Jr., L. B.; Zehn, D.; Egawa, T.; Bengsch, B.; Klein-Geltink, R.; Jenuwein, T.; Pearce, E. J.; Pearce, E. L.: Acetate Promotes T Cell Effector Function during Glucose Restriction. Cell Reports 27, pp. 2063 - 2074 (2019)
  5. 2018
    Journal Article
    Santos-Barriopedro, I.; Bosch-Presegue, L.; Marazuela-Duque, A.; de la Torre, C.; Colomer, C.; Vazquez, B. N.; Fuhrmann, T.; Martinez-Pastor, B.; Lu, W.; Braun, T. et al.; Bober, E.; Jenuwein, T.; Serrano, L.; Esteller, M.; Chen, Z.; Barcelo-Batllori, S.; Mostoslavsky, R.; Espinosa, L.; Vaquero, A.: SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-kappa B pathway. NATURE COMMUNICATIONS 9, p. 101 (2018)
  6. 2017
    Journal Article
    Costantino, S.; Paneni, F.; Virdis, A.; Hussain, S.; Mohammed, S. A.; Capretti, G.; Akhmedov, A.; Dalgaard, K.; Chiandotto, S.; Pospisilik, J. A. et al.; Jenuwein, T.; Giorgio, M.; Volpe, M.; Taddei, S.; Lüscher, T. F.; Cosentino, F.: Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity. European Heart Journal 40, pp. 383 - 391 (2017)
  7. Journal Article
    Fan, Z.; Li, L.; Li, M.; Zhang, X.; Hao, C.; Yu, L.; Zeng, S.; Xu, H.; Fang, M.; Shen, A. et al.; Jenuwein, T.; Xu, Y.: The Histone Methyltransferase Suv39h2 Contributes to Nonalcoholic Steatohepatitis in Mice. Hepatology 65, p. 1904 (2017)
  8. Journal Article
    Nguyen, D. T.; Voon, H. P. J.; Xella, B.; Scott, C.; Clynes, D.; Babbs, C.; Ayyub, H.; Kerry, J.; Sharpe, J. A.; Sloane‐Stanley, J. A. et al.; Butler, S.; Fisher, C. A.; Gray, N. E.; Jenuwein, T.; Higgs, D. R.; Gibbons, R. J.: The chromatin remodelling factor ATRX suppresses R-loops in transcribed telomeric repeats. EMBO Reports 18, pp. 914 - 928 (2017)
  9. Journal Article
    Yang, G.; Weng, X.; Zhao, Y.; Zhang, X.; Hu, Y.; Dai, X.; Liang, P.; Wang, P.; Ma, L.; Sun, X. et al.; Hou, L.; Xu, H.; Fang, M.; Li, Y.; Jenuwein, T.; Xu, Y.; Sun, A.: The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction. Nature Communications 8, p. 14941 (2017)
  10. Journal Article
    Camacho, O. V.; Galan, C.; Swist-Rosowska, K.; Ching, R.; Gamalinda, M.; Karabiber, F.; La Rosa-Velazquez, I. D.; Engist, B.; Koschorz, B.; Shukeir, N. et al.; Onishi-Seebacher, M.; van de Nobelen, S.; Jenuwein, T.: Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome assocation and RNA:DNA hybrid formation. eLife, p. e25293 (2017)
  11. 2016
    Journal Article
    Allis, C. D.; Jenuwein, T.: The molecular hallmarks of epigenetic control. Nature Reviews Genetics, pp. 487 - 500 (2016)
  12. Journal Article
    Hiragami-Hamada, K.; Sörös, S.; Nikolov, M.; Wilkins, B.; Kreuz, S.; Chen, C.; De La Rosa-Velazquez, I. A.; Zenn, H. M.; Kost, N.; Pohl, W. et al.; Chernev, A.; Schwarzer, D.; Jenuwein, T.; Lorincz, M.; Zimmermann, B.; Walla, P. J.; Neumann, H.; Baubec, T.; Urlaub, H.; Fischle, W.: Dynamic and flexible H3K9me3 bridging via HP1beta dimerization establishes a plastic state of condensed chromatin. Nature Communications 7, 11310 (2016)
  13. Journal Article
    Dalgaard, K.; Landgraf, K.; Heyne, S.; Lempradl, A.; Longinotto, J.; Gossens, K.; Ruf, M.; Orthofer, M.; Strogantsev, R.; Selvaraj, M. et al.; Lu, T. T.-H.; Casas, E.; Teperino, R.; Surani, M. A.; Zvetkova, I.; Rimmington, D.; Tung, Y.C. L.; Lam, B.; Larder, R.; Yeo, G. S.H.; O’Rahilly, S.; Vavouri, T.; Whitelaw, E.; Penninger, J. M.; Jenuwein, T.; Cheung, C.-L.; Ferguson-Smith, A. C.; Coll, A. P.; Körner, A.; Pospisilik, J. A.: Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity. Cell 164, pp. 353 - 364 (2016)
  14. Journal Article
    Foti, R.; Gnan, S.; Cornacchia, D.; Dileep, V.; Bulut-Karslioglu, A.; Diehl, S.; Buness, A.; Klein, F. A.; Huber, W.; Johnstone, E. et al.; Loos, R.; Bertone, P.; Gilbert, D. M.; Manke, T.; Jenuwein, T.; Buonomo, S. C.B.: Nuclear Architecture Organized by Rif1 Underpins the Replication-Timing Program. Molecular Cell 61, pp. 260 - 273 (2016)
  15. 2015
    Journal Article
    Voon, H. P.J.; Hughes, J. R.; Rode, C.; De La Rosa-Velázquez, I. A.; Jenuwein, T.; Feil, R.; Higgs, D. R.; Gibbons, R. J.: ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes. Cell Reports 11, pp. 405 - 418 (2015)
  16. 2014
    Journal Article
    Bulut-Karslioglu, A.; De La Rosa-Valázquez, I. A.; Ramirez, F.; Barenboim, M.; Onishi-Seebacher, M.; Arand, J.; Galán, C.; Winter, G. E.; Engist, B.; Gerle, B. et al.; O'Sullivan, R. J.; Martens, J. H. A.; Walter, J.; Manke, T.; Lachner, M.; Jenuwein, T.: Suv39h-Dependent H3K9me3 Marks Intact Retrotransposons and Silences LINE Elements in Mouse Embryonic Stem Cells. Molecular Cell 55, pp. 277 - 290 (2014)
  17. Journal Article
    Sone, K.; Piao, L.; Nakakido, M.; Ueda, K.; Jenuwein, T.; Nakamura, Y.; Hamamoto, R.: Critical role of lysine 134 methylation on histone H2AX for γ-H2AX production and DNA repair. Nature Communication 5, pp. 5691 - 5702 (2014)
  18. 2013
    Journal Article
    Millanes-Romero, A.; Herranz, N.; Perrera, V.; Iturbide, A.; Loubat-Casanovas, J.; Jesús, G.; Jenuwein, T.; García de Herreros, A.; Peiró, S.: Regulation of Heterochromatin Transcription by Snail1/LOXL2 during Epithelial-to-Mesenchymal Transition. Molecular Cell 52, pp. 746 - 757 (2013)
  19. 2012
    Journal Article
    Bulut-Karslioglu, A.; Perrera, V.; Scaranaro, M.; de la Rosa-Velazquez, I. A.; van de Nobelin, S.; Shukeir, N.; Popow, J.; Gerle, B.; Opravil, S.; Pagani, M. et al.; Meidhof, S.; Brabletz, T.; Manke, T.; Lachner, M.; Jenuwein, T.: A transcription factor-based mechanism for mouse heterochromatin formation. Nature Structural & Molecular Biology 19, pp. 1023 - 1030 (2012)
  20. Journal Article
    Pinheiro, I.; Margueron, R.; Shukeir, N.; Eisold, M.; Fritzsch, C.; Richter, F. M.; Mittler, G.; Genoud, C.; Goyama, S.; Kurokawa, M. et al.; Son, J.; Reinberg, D.; Lachner, M.; Jenuwein, T.: Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity. Cell 150, pp. 948 - 960 (2012)
  21. Journal Article
    Arand, J.; Spieler, D.; Karius, T.; Branco, M. R.; Meilinger, D.; Meissner, A.; Jenuwein, T.; Xu, G.; Leonhardt, H.; Wolf, V. et al.; Walter, J.: In vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases. PLoS Genetics 8, p. e1002750 - e1002750 (2012)
  22. 2011
    Journal Article
    Jin, C.; Li, J.; Green, C. D.; Yu, X.; Tang, X.; Han, D.; Xian, B.; Wang, D.; Huang, X.; Cao, X. et al.; Yan, Z.; Hou, L.; Liu, J.; Shukeir, N.; Khaitovich, P.; Chen, C. D.; Zhang, H.; Jenuwein, T.; Han, J.-d. J.: Histone Demethylase UTX-1 Regulates C.elegans Life Span by Targeting the Insulin/IGF-1 Signaling Pathway. Cell Metabolism 14, pp. 161 - 172 (2011)
  23. Journal Article
    Lu, F.; Cui, X.; Zhang, S.; Jenuwein, T.; Cao, X.: Arabidopsis REF6 is a histone H3 lysine 27 demethylase. Nature Genetics 43, pp. 715 - 719 (2011)
  24. 2010
    Journal Article
    Feng, W.; Yonezawa, M.; Ye, J.; Jenuwein, T.; Grummt, I.: PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation. Nature Structural & Molecular Biology 17, pp. 445 - 450 (2010)
  25. Journal Article
    Huang, J.; Dorsey, J.; Schikov, S.; Zhang, X.; Jenuwein, T.; Reinberg, D.; Berger, S.: G9a and Glp Methylate lysine 373 in the Tumor Suppressor p53. Journal of Biological Chemistry 285, pp. 9636 - 9641 (2010)
  26. Journal Article
    Reimann, M.; Lee, S.; Loddenkemper, C.; Dörr, J. R.; Tabor, V.; Aichele, P.; Stein, H.; Dörken, B.; Jenuwein, T.; Schmitt, C. A.: Tumor Stroma-Derived TGF-β Limits Myc-Driven Lymphoma-genesis via Suv39h1-Dependent Senescence. Cancer Cell 17, pp. 262 - 272 (2010)
  27. Journal Article
    Chen, L.; Li, Z.; Zwolinska, A. K.; Smith, M. A.; Cross, B.; Koomen, J.; Yuan, Z.-M.; Jenuwein, T.; Marine, J.-C.; Wright, K. L. et al.; Chen, J.: MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output. The EMBO Journal 29, pp. 2538 - 2552 (2010)
  28. Journal Article
    Fodor, B. D.; Shukeir, N.; Reuter, G.; Jenuwein, T.: Mammalian Su(var) Genes in Chromatin Control. Annual Review of Cell and Developmental Biology 26, pp. 471 - 501 (2010)
  29. 2009
    Journal Article
    Pauler, F. M.; Sloane, M. A.; Huang, R.; Regha, K.; Koerner, M. V.; Tamir, I.; Sommer, A.; Aszodi, A.; Jenuwein, T.: H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome. Genome Research 19, pp. 221 - 233 (2009)
  30. Journal Article
    Savarese, F.; Dávila, A.; Nechanitzky, R.; De La Rosa-Velazquez, I.; Pereira, C. F.; Engelke, R.; Takahashi, K.; Jenuwein, T.; Kohwi-Shigematsue, T.; Fisher, A. et al.; Grosschedl, R.: Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression. Genes & Development 23, pp. 2625 - 2638 (2009)
 
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