Hilgers Lab

Alfonso-Gonzalez, C.; Hilgers, V.: (Alternative) transcription start sites as regulators of RNA processing. Trends in Cell Biology (2024)
Alfonso-Gonzalez, C.; Arrigoni, L.; Ozbulut, H. C.; Falk, S.; Bönisch, U.; Hilgers, V.: Identification of regulatory links between transcription and RNA processing with long-read sequencing. STAR Protocols 4, 102505 (2023)
Alfonso-Gonzalez, C.; Legnini, I.; Holec, S.; Arrigoni, L.; Ozbulut, H. C.; Mateos, F.; Koppstein, D.; Rybak-Wolf, A.; Bönisch, U.; Rajewsky, N. et al.; Hilgers, V.: Sites of transcription initiation drive mRNA isoform selection. Cell 186, pp. 2438 - 2455 (2023)
Carrasco, J.; Mateos, F.; Hilgers, V.: A critical developmental window for ELAV/Hu-dependent mRNA signatures at the onset of neuronal differentiation. Cell Reports 41, 111542 (2022)
Grzejda, D.; Mach, J.; Schweizer, J. A.; Hummel, B.; Rezansoff, A. M.; Eggenhofer, F.; Panhale, A.; Lalioti, M.-E.; Cabezas-Wallscheid, N.; Backofen, R. et al.; Felsenberg, J.; Hilgers, V.: The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity. Science Advances 8, eabo5578 (2022)
Hilgers, V.: Regulation of neuronal RNA signatures by ELAV/Hu proteins. Wiley interdisciplinary reviews: WIREs RNA, e1733 (2022)
Castro Alvarez, J. J.; Revel, M.; Carrasco Sala, J.; Cléard, F.; Pauli, D.; Hilgers, V.; Karch, F.; Maeda, R. K.: Repression of the Hox gene abd-A by ELAV-mediated Transcriptional Interference. PLoS Genetics 17 (11), e1009843 (2021)
Carrasco, J.; Rauer, M.; Hummel, B.; Grzejda, D.; Alfonso-Gonzalez, C.; Lee, Y.; Wang, Q.; Puchalska, M.; Mittler, G.; Hilgers, V.: ELAV and FNE Determine Neuronal Transcript Signatures through EXon-Activated Rescue. Molecular Cell 80, pp. 156 - 163 (2020)
Wang, Q.; Taliaferro, J. M.; Klibaite, U.; Hilgers, V.; Shaevitz, J. W.; Rio, D. C.: The PSI-U1 snRNP interaction regulates male mating behavior in Drosophila. Proceedings of the National Academy of Sciences of the United States of America 113, pp. 5269 - 5274 (2016)
Oktaba, K.; Zhang, W.; Lotz, T. S.; Jun, D. J.; Lemke, S. B.; Ng, S. P.; Esposito, E.; Levine, M.; Hilgers, V.: ELAV links paused Pol II to alternative polyadenylation in the Drosophila nervious system. Molecular Cell 57, pp. 341 - 348 (2015)
Hilgers, V.: Alternative polyadenylation couples to transcription initiation: Insights from ELAV-mediated 3' UTR extension. RNA Biology 12, pp. 918 - 921 (2015)
Hilgers, V.; Lemke, S. B.; Levine, M.: ELAV mediates 3' UTR extension in the Drosophila nervous system. Proceedings of the National Academy of Sciences of the United States of America 26, pp. 2259 - 2264 (2012)
Hilgers, V.; Perry, M. W.; Hendrix, D.; Stark, A.; Levine, M.; Haley, B.: Neural-specific elongation of 3' UTRs during Drosophila development. Proceedings of the National Academy of Sciences of the United States of America 108, pp. 15864 - 15869 (2011)
Hilgers, V.; Bushati, N.; Cohen, S. M.: Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis. PLoS Biology 8, p. e1000396 (2010)
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