A new model for transplantation of blood stem cells

Thymopoiesis is a very complex and dynamic process. The thymus is important for the differentiation and maturation of progenitor cells into self-tolerant T-lymphocytes. Failures in thymus development or thymus function cause immunodeficiencies; however, many genetic lesions underlying these diseases are still unknown. At the institute, researchers aim at a better understanding of the molecular and cellular mechanisms of thymus development.