Publications
Lab Lämmermann
2022
Surprises from Intravital Imaging of the Innate Immune Response. Annual Review of Cell and Developmental Biology 38, pp. 18.1 - 18.23 (2022)
100 Hz ROCS microscopy correlated with fluorescence reveals cellular dynamics on different spatiotemporal scales. Nature Communications 13, 1758 (2022)
Macrophage network dynamics depend on haptokinesis for optimal local surveillance. eLife 11, e75354, pp. 1 - 32 (2022)
Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine. Nature Neuroscience 25, pp. 295 - 305 (2022)
Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity. The journal of allergy and clinical immunology: official publication of the American Academy of Allergy, Asthma and Immunology 149, pp. 388 - 399 (2022)
2021
Microbiota-dependent increase in δ-valerobetaine alters neuronal function and is responsible for age-related cognitive decline. Nature aging 1, pp. 1127 - 1136 (2021)
Positive feedback amplification in swarming immune cell populations. Current Opinion in Cell Biology 72, pp. 156 - 162 (2021)
Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Immunity 54, pp. 1494 - 1510 (2021)
Neutrophils self-limit swarming to contain bacterial growth in vivo. Science 372, eabe7729 (2021)
Upregulation of VCAM-1 in lymphatic collectors supports dendritic cell entry and rapid migration to lymph nodes in inflammation. Journal of Experimental Medicine 218, p. e20201413 (2021)
2020
T cells: Bridge-and-Channel Commute to the White Pulp. Immunity 52, pp. 721 - 723 (2020)
Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics. Immunity 52, pp. 313 - 327 (2020)
2019
Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage. Cell 177, pp. 541 - 555 (2019)
Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation. Circulation 139, pp. 918 - 931 (2019)
A Subset of Skin Macrophages Contributes to the Seruveillance and Regeneration of Local Nerves. Immunity 50, pp. 1482 - 1497 (2019)
Concepts of GPCR-controlled navigation in the immune system. Immunological Reviews 289, pp. 205 - 231 (2019)
2018
Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset. Blood 131, pp. 1858 - 1869 (2018)
Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function. Proceedings of the National Academy of Sciences of the United States of America 115, pp. E9630 - E9639 (2018)
2017
Platelets, On Your Makrs, Gest Set, Migrate! Cell 171, pp. 1256 - 1258 (2017)
Cell migration: Arraying neutrophils in swarms. nature biomedical engineering 1, p. 0100 (2017)
2016
Continuous volumetric imaging via an optical phase-locked ultrasound lens. Nature methods 12, pp. 759 - 762 (2016)
Neutrophil swarming: an essential process of the neutrophil tissue response. Immunological Reviews 273, pp. 76 - 93 (2016)
2014
Tuning of antigen sensitivity by T cell receptor-dependent negative feedback controls T cell effector function inflammed tissues. Immunity 40, pp. 235 - 247 (2014)
The multiple faces of leukocyte interstitial migration. Springer Seminars in Immunopathology 36, pp. 227 - 251 (2014)
2013
Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival. Proceedings of the National Academy of Sciences of the United States of America 110, pp. E2915 - E2924 (2013)
Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo. Nature 498, pp. 371 - 375 (2013)
2012
A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread. Cell 150, pp. 1235 - 1248 (2012)
Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo. Proceedings of the National Academy of Sciences of the United States of America 109, pp. E889 - E897 (2012)
2011
In vitro analysis of chemotactic leukocyte migration in 3D environments. Methods in Molecular Biology 32, pp. 703 - 713 (2011)
2010
Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells. Immunity 32 (5), pp. 703 - 713 (2010)
2009
Adaptive force transmission in amoeboid cell migration. Nature Cell Biology 11, pp. 1438 - 1443 (2009)
Mechanical modes of 'amoeboid' cell migration. Current Opinion in Cell Biology 21, pp. 636 - 644 (2009)
Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration. Blood 113, pp. 5703 - 5710 (2009)
Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells. Blood 113, pp. 5801 - 5810 (2009)
2008
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin. Journal of Clinical Investigation (New York, NY) 118, pp. 2438 - 2447 (2008)
Rapid leukocyte migration by integrin-independent flowing and squeezing. Nature 453, pp. 51 - 55 (2008)
The microanatomy of T-cell responses. Immunological Reviews 221, pp. 26 - 43 (2008)
The extracellular matrix of the spleen as a potential organizer of immune cell compartments. Seminars in Immunology 20, pp. 4 - 13 (2008)
2006
β1 integrins: zip codes and signaling relay for blood cells. Current Opinion in Cell Biology 18, pp. 482 - 490 (2006)
γ-Parvin Is Dispensable for Hematopoiesis, Leukocyte Trafficking, and T-Cell-Dependent Antibody Response. Molecular and Cellular Biology (Washington, DC) 26, pp. 1817 - 1825 (2006)