Publications
Lab Lämmermann
2024
187, pp. 5316 - 5335 (2024)
Neutrophil trapping and nexocytosis, mast cell-mediated processes for inflammatory signal relay. Cell 204, e65690 (2024)
Targeted Metabolomics on Rare Primary Cells. Journal of Visualized Experiments 27, 108656 (2024)
Arp2/3 complex and the pentose phosphate pathway regulate late phases of neutrophil swarming. iScience 2023
Slow integrin-dependent migration organizes networks of tissue-resident mast cells. Nature Immunology (2023)
4, 102013 (2023)
Analyzing trogocytosis of T lymphocytes by flow cytometry and confocal microscopy. STAR Protocols 95, pp. 4325 - 4334 (2023)
LC-MS-Based Targeted Metabolomics for FACS-Purified Rare Cells. Analytical Chemistry 2022
13, 1039803 (2022)
Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions. Frontiers in immunology 13, 6459 (2022)
Differential trafficking of ligands trogocytosed via CD28 versus CTLA4 promotes collective cellular control of co-stimulation. Nature Communications 38, pp. 18.1 - 18.23 (2022)
Surprises from Intravital Imaging of the Innate Immune Response. Annual Review of Cell and Developmental Biology 221, e202103207 (2022)
A two-step search and run response to gradients shapes leukocyte navigation in vivo. Journal of Cell Biology 604, pp. 740 - 748 (2022)
Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature 10, 871789 (2022)
Neutrophils: Amoeboid Migration and Swarming Dynamics in Tissues. Frontiers in Cell and Developmental Biology 13, 1758 (2022)
100 Hz ROCS microscopy correlated with fluorescence reveals cellular dynamics on different spatiotemporal scales. Nature Communications 11, e75354, pp. 1 - 32 (2022)
Macrophage network dynamics depend on haptokinesis for optimal local surveillance. eLife 25, pp. 295 - 305 (2022)
Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine. Nature Neuroscience 2021
1, pp. 1127 - 1136 (2021)
Microbiota-dependent increase in δ-valerobetaine alters neuronal function and is responsible for age-related cognitive decline. Nature aging 72, pp. 156 - 162 (2021)
Positive feedback amplification in swarming immune cell populations. Current Opinion in Cell Biology 54, pp. 1494 - 1510 (2021)
Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Immunity 372, eabe7729 (2021)
Neutrophils self-limit swarming to contain bacterial growth in vivo. Science 149, pp. 388 - 399 (2021)
Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity. The journal of allergy and clinical immunology: official publication of the American Academy of Allergy, Asthma and Immunology 218, p. e20201413 (2021)
Upregulation of VCAM-1 in lymphatic collectors supports dendritic cell entry and rapid migration to lymph nodes in inflammation. Journal of Experimental Medicine 2020
52, pp. 721 - 723 (2020)
T cells: Bridge-and-Channel Commute to the White Pulp. Immunity 52, pp. 313 - 327 (2020)
Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics. Immunity 2019
177, pp. 541 - 555 (2019)
Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage. Cell 139, pp. 918 - 931 (2019)
Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation. Circulation 50, pp. 1482 - 1497 (2019)
A Subset of Skin Macrophages Contributes to the Seruveillance and Regeneration of Local Nerves. Immunity 289, pp. 205 - 231 (2019)
Concepts of GPCR-controlled navigation in the immune system. Immunological Reviews 2018
131, pp. 1858 - 1869 (2018)
Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset. Blood 115, pp. E9630 - E9639 (2018)
Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function. Proceedings of the National Academy of Sciences of the United States of America 2017
171, pp. 1256 - 1258 (2017)
Platelets, On Your Makrs, Gest Set, Migrate! Cell 1, p. 0100 (2017)
Cell migration: Arraying neutrophils in swarms. nature biomedical engineering 2016
12, pp. 759 - 762 (2016)
Continuous volumetric imaging via an optical phase-locked ultrasound lens. Nature methods 273, pp. 76 - 93 (2016)
Neutrophil swarming: an essential process of the neutrophil tissue response. Immunological Reviews 2014
40, pp. 235 - 247 (2014)
Tuning of antigen sensitivity by T cell receptor-dependent negative feedback controls T cell effector function inflammed tissues. Immunity 36, pp. 227 - 251 (2014)
The multiple faces of leukocyte interstitial migration. Springer Seminars in Immunopathology 2013
110, pp. E2915 - E2924 (2013)
Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival. Proceedings of the National Academy of Sciences of the United States of America 498, pp. 371 - 375 (2013)
Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo. Nature 2012
150, pp. 1235 - 1248 (2012)
A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread. Cell 109, pp. E889 - E897 (2012)
Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo. Proceedings of the National Academy of Sciences of the United States of America 2011
32, pp. 703 - 713 (2011)
In vitro analysis of chemotactic leukocyte migration in 3D environments. Methods in Molecular Biology 2010
32 (5), pp. 703 - 713 (2010)
Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells. Immunity 2009
11, pp. 1438 - 1443 (2009)
Adaptive force transmission in amoeboid cell migration. Nature Cell Biology 21, pp. 636 - 644 (2009)
Mechanical modes of 'amoeboid' cell migration. Current Opinion in Cell Biology 113, pp. 5703 - 5710 (2009)
Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration. Blood 113, pp. 5801 - 5810 (2009)
Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells. Blood 2008
118, pp. 2438 - 2447 (2008)
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin. Journal of Clinical Investigation (New York, NY) 453, pp. 51 - 55 (2008)
Rapid leukocyte migration by integrin-independent flowing and squeezing. Nature 221, pp. 26 - 43 (2008)
The microanatomy of T-cell responses. Immunological Reviews 20, pp. 4 - 13 (2008)
The extracellular matrix of the spleen as a potential organizer of immune cell compartments. Seminars in Immunology 2006
18, pp. 482 - 490 (2006)
β1 integrins: zip codes and signaling relay for blood cells. Current Opinion in Cell Biology 26, pp. 1817 - 1825 (2006)
γ-Parvin Is Dispensable for Hematopoiesis, Leukocyte Trafficking, and T-Cell-Dependent Antibody Response. Molecular and Cellular Biology (Washington, DC)