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Journal Article (64)

  1. 2020
    Journal Article
    Wang, Y.; Zolotarev, N.; Yang, C.-Y.; Rambold, A.; Mittler, G.; Grosschedl, R.: A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin. Immunity 53, pp. 1 - 17 (2020)
  2. Journal Article
    Kucinski, I.; Wilson, N. K.; Hannah, R.; Kinston, S. J.; Cauchy, P.; Lenaerts, A.; Grosschedl, R.; Göttgens, B.: Interactions between lineage-associated transcription factors govern haematopoietic progenitor states. The EMBO Journal, p. e104983 (2020)
  3. Journal Article
    Derecka, M.; Herman, J. S.; Cauchy, P.; Ramamoorthy, S.; Lupar, E.; Grün, D.; Grosschedl, R.: EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential. Nature 21, pp. 261 - 273 (2020)
  4. Journal Article
    Kapoor, T.; Corrado, M.; Pearce, E. L.; Pearce, E. J.; Grosschedl, R.: MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells. Scientific Reports 10 (2020)
  5. Journal Article
    Ramamoorthy, S.; Kometani, K.; Herman, J. S.; Bayer, M.; Boller, S.; Edwards-Hicks, J.; Ramachandran, H.; Li, R.; Klein-Geltink, R.; Pearce, E. L. et al.; Grün, D.; Grosschedl, R.: EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism. Genes and Development 34, pp. 1503 - 1519 (2020)
  6. 2018
    Journal Article
    Tinterri, A.; Menardy, F.; Diana, M. A.; Lokmane, L.; Keita, M.; Coulpier, F.; Lemoine, S.; Mailhes, C.; Mathieu, B.; Merchan-Sala, P. et al.; Campbell, K.; Gyory, I.; Grosschedl, R.; Popa, D.; Garel, S.: Active intermixing of indirect and direct neurons builds the striatal mosaic. Nature Communications 9, p. 4725 (2018)
  7. Journal Article
    Yanai, H.; Chiba, S.; Hangai, S.; Kometani, K.; Inoue, A.; Kimura, Y.; Abe, T.; Kiyonari, H.; Nishio, J.; Taguchi-Atarashi, N. et al.; Mizushima, Y.; Negishi, H.; Grosschedl, R.; Taniguchi, T.: Revisiting the role of IRF3 in inflammation and immunity by conditional and specifically targeted gene ablation in mice. Proceedings of the National Academy of Sciences of the United States of America 115, pp. 5253 - 5258 (2018)
  8. Journal Article
    Boller, S.; Li, R.; Grosschedl, R.: Defining B Cell Chromatin: Lessons from EBF1. Trends in Genetics 34, pp. 257 - 269 (2018)
  9. Journal Article
    Li , R.; Cauchy, P.; Ramamoorthy, S.; Boller, S.; Chevez, L.; Grosschedl, R.: Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming. Genes and Development 32, pp. 96 - 111 (2018)
  10. Journal Article
    Andreani, V.; Ramamoorthy, S.; Pandey, A.; Lupar, E.; Nutt, S. L.; Lämmermann, T.; Grosschedl, R.: Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function. Proceedings of the National Academy of Sciences of the United States of America 115, pp. E9630 - E9639 (2018)
  11. Journal Article
    Musa, Y. R.; Boller, S.; Puchalska, M.; Grosschedl, R.; Mittler, G.: Comprehensive Proteomic Investigation of Ebf1 Heterozygosity in Pro-B Lymphocytes Ulilizing Data Independent Acquisition. Journal of Proteome Research 17, pp. 76 - 85 (2018)
  12. 2017
    Journal Article
    Rodríguez-Gil, A.; Ritter, O.; Saul, V. V.; Wilhelm, J.; Yang, C.-Y.; Grosschedl, R.; Imai, Y.; Kuba, K.; Kracht, M.; Schmitz, M. L.: The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription. Scientific Reports, p. 3547 (2017)
  13. 2016
    Journal Article
    Yang, C.-Y.; Ramamoorthy, S.; Boller, S.; Rosenbaum, M.; Gil, A. R.; Mittler, G.; Imai, Y.; Kuba, K.; Grosschedl, R.: Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis. Genes and Development 30, pp. 2310 - 2324 (2016)
  14. Journal Article
    Schnappauf, O.; Beyes, S.; Dertmann, A.; Freihen, V.; Frey, P.; Rose, K.; Michoel, T.; Grosschedl, R.; Hecht, A.: Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing. Biochimica et Biophysica Acta (BBA) 1859, pp. 1353 - 1367 (2016)
  15. Journal Article
    Hilde, K. L.; Levine, A. J.; Hinckley, C. A.; Montgomery, J. M.; Gullo, M.; Driscoll, S. P.; Grosschedl, R.; Kohwi, Y.; Kohwi-Shigematsu, T.; Pfaff, S.: Satb2 Is Required for the Development of a Spinal Exteroceptive Microcircuit that Modulates Limb Position. Neuron 91, pp. 763 - 776 (2016)
  16. Journal Article
    Boller, S.; Ramamoorthy, S.; Akbas, D.; Nechanitzky, R.; Burger, L.; Murr, R.; Schübeler, D.; Grosschedl, R.: Pioneering Activity of the C-Terminal Domain of EBF1 Shapes the Chromatin Landscape for B Cell Programming. Immunity 44, pp. 527 - 541 (2016)
  17. 2015
    Journal Article
    Leone, D. P.; Heavner, W. E.; Ferenczi, E. A.; Dobreva, G.; Huguendard, J. R.; Grosschedl, R.; McConnell, S. K.: Satb2 Regulates the differntiationof Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex. Cerebral Cortex 25, pp. 3406 - 3419 (2015)
  18. Journal Article
    Ramachandran, H.; Herfurth, K.; Grosschedl, R.; Schäfer, T.; Walz, G.: SUMOylation Blocks the Ubiquitin-Mediated Degradatoin of the Nephronophthisis Gene Product Glis2/NPHP7. Plos One 10, p. e0130275 (2015)
  19. 2014
    Journal Article
    Boller, S.; Grosschedl, R.: The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function. Immunological Reviews, pp. 102 - 115 (2014)
  20. Journal Article
    Grosschedl, R.: Establishment and Maintenance of B cell Identity. Cold Spring Harbor Symposia on Quantitative Biology 78, pp. 23 - 30 (2014)
  21. Journal Article
    Okosun, J.; Bödör, C.; Wang, J.; Araf, S.; Yang, C.-Y.; Pan, C.; Boller, S.; Cittaro, D.; Bozek, M.; Iqbal, S. et al.; Matthews, J.; Wrench, D.; Marzec, J.; Tawana, K.; Popov, N.; O'riain, C.; O'Shea, D.; Carlotti, E.; Davies, A.; Lawrie, C. H.; Matolcsy, A.; Calaminici, M.; Norton, A.; Byers, R. J.; Mein, C.; Stupka, E.; Lister, T. A.; Lenz, G.; Montoto, S.; Gribben, J. G.; Fan, Y.; Grosschedl, R.; Chelala, C.; Fitzgibbon, J.: Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nature Genetics 46, pp. 176 - 181 (2014)
  22. Journal Article
    Rosenbaum, M.; Andreani, V.; Kapoor, T.; Herp, S.; Flach, H.; Duchniewicz, M.; Grosschedl, R.: MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress. Genes & Development 28, pp. 1165 - 1178 (2014)
  23. 2013
    Journal Article
    Nechanitzky, R.; Akbas, D.; Scherer, S.; Györy, I.; Hoyler, T.; Ramamoorthy, S.; Diefenbach, A.; Grosschedl, R.: Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells. Nature Immunology 14, pp. 867 - 875 (2013)
  24. Journal Article
    Lokmane, L.; Proville, R.; Narboux-Neme, N.; Györy, I.; Keita, M.; Mailhes, C.; Léna, C.; Gaspar, P.; Grosschedl, R.; Garel, S.: Sensory Map Transfer to the Neocrotex Relies on Pretarget Ordering of Thalamic Axons. Current Biology 23, pp. 810 - 816 (2013)
  25. Journal Article
    Zee, T.; Boller, S.; Györy, I.; Makinistoglu, M. P.; Tuckermann, J. P.; Grosschedl, R.; Karsenty, G.: The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner. FEBS Letters 587, pp. 711 - 716 (2013)
  26. 2012
    Journal Article
    Srinivasan, K.; Leone, D. P.; Bateson, R. K.; Dobreva, G.; Kohwi, Y.; Kohwi-Shigematsu, T.; Grosschedl, R.; McConnell, S. K.: A network of genetic repression and derepression specifies projection fates in the developing neocortex. Proceedings of the National Academy of Sciences U.S.A. 109, pp. 19071 - 19078 (2012)
  27. Journal Article
    Nechanitzky, R.; Dávila, A.; Savarese, F.; Fietze, S.; Grosschedl, R.: Satb1 and Satb2 Are Dispensable for X Chromosome Inactivation in Mice. Developmental Cell 23, pp. 866 - 871 (2012)
  28. Journal Article
    Skokowa, J.; Klimiankou, M.; Klimenkova, O.; Lan, D.; Gupta, K.; Hussein, K.; Carrizosa, E.; Kusnetsova, I.; Li, Z.; Sustmann, C. et al.; Ganser, A.; Zeidler, C.; Kreipe, H.-H.; Burkhardt, J.; Grosschedl, R.; Welte, K.: Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis. Nature Medicine 18, pp. 1550 - 1559 (2012)
  29. Journal Article
    Györy, I.; Boller, S.; Nechanitzky, R.; Mandel, E.; Pott, S.; Liu, E.; Grosschedl, R.: Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells. Genes & Development 26, pp. 668 - 682 (2012)
  30. Journal Article
    Wei, J.; Shi, Y.; Zheng, L.; Zhou, B.; Inose, H.; Wang, J.; Guo, X. E.; Grosschedl, R.; Karsenty, G.: miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. The Journal of Cell Biology 197, pp. 509 - 521 (2012)
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