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Journal Article (64)

1. 2020
   MPG.PuRe

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   Wang, Y.; Zolotarev, N.; Yang, C.-Y.; Rambold, A.; Mittler, G.; Grosschedl, R.: A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin. Immunity 53, pp. 1 - 17 (2020)
2. MPG.PuRe

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   Kucinski, I.; Wilson, N. K.; Hannah, R.; Kinston, S. J.; Cauchy, P.; Lenaerts, A.; Grosschedl, R.; Göttgens, B.: Interactions between lineage-associated transcription factors govern haematopoietic progenitor states. The EMBO Journal, p. e104983 (2020)
3. MPG.PuRe

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   Derecka, M.; Herman, J. S.; Cauchy, P.; Ramamoorthy, S.; Lupar, E.; Grün, D.; Grosschedl, R.: EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential. Nature 21, pp. 261 - 273 (2020)
4. MPG.PuRe

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   Kapoor, T.; Corrado, M.; Pearce, E. L.; Pearce, E. J.; Grosschedl, R.: MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells. Scientific Reports 10 (2020)
5. MPG.PuRe

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   Ramamoorthy, S.; Kometani, K.; Herman, J. S.; Bayer, M.; Boller, S.; Edwards-Hicks, J.; Ramachandran, H.; Li, R.; Klein-Geltink, R.; Pearce, E. L. et al.; Grün, D.; Grosschedl, R.: EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism. Genes and Development 34, pp. 1503 - 1519 (2020)
6. 2018
   MPG.PuRe

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   Tinterri, A.; Menardy, F.; Diana, M. A.; Lokmane, L.; Keita, M.; Coulpier, F.; Lemoine, S.; Mailhes, C.; Mathieu, B.; Merchan-Sala, P. et al.; Campbell, K.; Gyory, I.; Grosschedl, R.; Popa, D.; Garel, S.: Active intermixing of indirect and direct neurons builds the striatal mosaic. Nature Communications 9, p. 4725 (2018)
7. MPG.PuRe

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   Yanai, H.; Chiba, S.; Hangai, S.; Kometani, K.; Inoue, A.; Kimura, Y.; Abe, T.; Kiyonari, H.; Nishio, J.; Taguchi-Atarashi, N. et al.; Mizushima, Y.; Negishi, H.; Grosschedl, R.; Taniguchi, T.: Revisiting the role of IRF3 in inflammation and immunity by conditional and specifically targeted gene ablation in mice. Proceedings of the National Academy of Sciences of the United States of America 115, pp. 5253 - 5258 (2018)
8. MPG.PuRe

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   Boller, S.; Li, R.; Grosschedl, R.: Defining B Cell Chromatin: Lessons from EBF1. Trends in Genetics 34, pp. 257 - 269 (2018)
9. MPG.PuRe

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   Li , R.; Cauchy, P.; Ramamoorthy, S.; Boller, S.; Chevez, L.; Grosschedl, R.: Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming. Genes and Development 32, pp. 96 - 111 (2018)
10. MPG.PuRe

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    Andreani, V.; Ramamoorthy, S.; Pandey, A.; Lupar, E.; Nutt, S. L.; Lämmermann, T.; Grosschedl, R.: Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function. Proceedings of the National Academy of Sciences of the United States of America 115, pp. E9630 - E9639 (2018)
11. MPG.PuRe

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    Musa, Y. R.; Boller, S.; Puchalska, M.; Grosschedl, R.; Mittler, G.: Comprehensive Proteomic Investigation of Ebf1 Heterozygosity in Pro-B Lymphocytes Ulilizing Data Independent Acquisition. Journal of Proteome Research 17, pp. 76 - 85 (2018)
12. 2017
    MPG.PuRe

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    Rodríguez-Gil, A.; Ritter, O.; Saul, V. V.; Wilhelm, J.; Yang, C.-Y.; Grosschedl, R.; Imai, Y.; Kuba, K.; Kracht, M.; Schmitz, M. L.: The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription. Scientific Reports, p. 3547 (2017)
13. 2016
    MPG.PuRe

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    Yang, C.-Y.; Ramamoorthy, S.; Boller, S.; Rosenbaum, M.; Gil, A. R.; Mittler, G.; Imai, Y.; Kuba, K.; Grosschedl, R.: Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis. Genes and Development 30, pp. 2310 - 2324 (2016)
14. MPG.PuRe

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    Schnappauf, O.; Beyes, S.; Dertmann, A.; Freihen, V.; Frey, P.; Rose, K.; Michoel, T.; Grosschedl, R.; Hecht, A.: Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing. Biochimica et Biophysica Acta (BBA) 1859, pp. 1353 - 1367 (2016)
15. MPG.PuRe

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    Hilde, K. L.; Levine, A. J.; Hinckley, C. A.; Montgomery, J. M.; Gullo, M.; Driscoll, S. P.; Grosschedl, R.; Kohwi, Y.; Kohwi-Shigematsu, T.; Pfaff, S.: Satb2 Is Required for the Development of a Spinal Exteroceptive Microcircuit that Modulates Limb Position. Neuron 91, pp. 763 - 776 (2016)
16. MPG.PuRe

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    Boller, S.; Ramamoorthy, S.; Akbas, D.; Nechanitzky, R.; Burger, L.; Murr, R.; Schübeler, D.; Grosschedl, R.: Pioneering Activity of the C-Terminal Domain of EBF1 Shapes the Chromatin Landscape for B Cell Programming. Immunity 44, pp. 527 - 541 (2016)
17. 2015
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    Leone, D. P.; Heavner, W. E.; Ferenczi, E. A.; Dobreva, G.; Huguendard, J. R.; Grosschedl, R.; McConnell, S. K.: Satb2 Regulates the differntiationof Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex. Cerebral Cortex 25, pp. 3406 - 3419 (2015)
18. MPG.PuRe

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    Ramachandran, H.; Herfurth, K.; Grosschedl, R.; Schäfer, T.; Walz, G.: SUMOylation Blocks the Ubiquitin-Mediated Degradatoin of the Nephronophthisis Gene Product Glis2/NPHP7. Plos One 10, p. e0130275 (2015)
19. 2014
    MPG.PuRe

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    Boller, S.; Grosschedl, R.: The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function. Immunological Reviews, pp. 102 - 115 (2014)
20. MPG.PuRe
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    Grosschedl, R.: Establishment and Maintenance of B cell Identity. Cold Spring Harbor Symposia on Quantitative Biology 78, pp. 23 - 30 (2014)
21. MPG.PuRe
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    Okosun, J.; Bödör, C.; Wang, J.; Araf, S.; Yang, C.-Y.; Pan, C.; Boller, S.; Cittaro, D.; Bozek, M.; Iqbal, S. et al.; Matthews, J.; Wrench, D.; Marzec, J.; Tawana, K.; Popov, N.; O'riain, C.; O'Shea, D.; Carlotti, E.; Davies, A.; Lawrie, C. H.; Matolcsy, A.; Calaminici, M.; Norton, A.; Byers, R. J.; Mein, C.; Stupka, E.; Lister, T. A.; Lenz, G.; Montoto, S.; Gribben, J. G.; Fan, Y.; Grosschedl, R.; Chelala, C.; Fitzgibbon, J.: Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nature Genetics 46, pp. 176 - 181 (2014)
22. MPG.PuRe
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    Rosenbaum, M.; Andreani, V.; Kapoor, T.; Herp, S.; Flach, H.; Duchniewicz, M.; Grosschedl, R.: MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress. Genes & Development 28, pp. 1165 - 1178 (2014)
23. 2013
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    Nechanitzky, R.; Akbas, D.; Scherer, S.; Györy, I.; Hoyler, T.; Ramamoorthy, S.; Diefenbach, A.; Grosschedl, R.: Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells. Nature Immunology 14, pp. 867 - 875 (2013)
24. MPG.PuRe
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    Lokmane, L.; Proville, R.; Narboux-Neme, N.; Györy, I.; Keita, M.; Mailhes, C.; Léna, C.; Gaspar, P.; Grosschedl, R.; Garel, S.: Sensory Map Transfer to the Neocrotex Relies on Pretarget Ordering of Thalamic Axons. Current Biology 23, pp. 810 - 816 (2013)
25. MPG.PuRe
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    Zee, T.; Boller, S.; Györy, I.; Makinistoglu, M. P.; Tuckermann, J. P.; Grosschedl, R.; Karsenty, G.: The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner. FEBS Letters 587, pp. 711 - 716 (2013)
26. 2012
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    Srinivasan, K.; Leone, D. P.; Bateson, R. K.; Dobreva, G.; Kohwi, Y.; Kohwi-Shigematsu, T.; Grosschedl, R.; McConnell, S. K.: A network of genetic repression and derepression specifies projection fates in the developing neocortex. Proceedings of the National Academy of Sciences U.S.A. 109, pp. 19071 - 19078 (2012)
27. MPG.PuRe
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    Nechanitzky, R.; Dávila, A.; Savarese, F.; Fietze, S.; Grosschedl, R.: Satb1 and Satb2 Are Dispensable for X Chromosome Inactivation in Mice. Developmental Cell 23, pp. 866 - 871 (2012)
28. MPG.PuRe

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    Skokowa, J.; Klimiankou, M.; Klimenkova, O.; Lan, D.; Gupta, K.; Hussein, K.; Carrizosa, E.; Kusnetsova, I.; Li, Z.; Sustmann, C. et al.; Ganser, A.; Zeidler, C.; Kreipe, H.-H.; Burkhardt, J.; Grosschedl, R.; Welte, K.: Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis. Nature Medicine 18, pp. 1550 - 1559 (2012)
29. MPG.PuRe
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    Györy, I.; Boller, S.; Nechanitzky, R.; Mandel, E.; Pott, S.; Liu, E.; Grosschedl, R.: Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells. Genes & Development 26, pp. 668 - 682 (2012)
30. MPG.PuRe
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    Wei, J.; Shi, Y.; Zheng, L.; Zhou, B.; Inose, H.; Wang, J.; Guo, X. E.; Grosschedl, R.; Karsenty, G.: miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. The Journal of Cell Biology 197, pp. 509 - 521 (2012)