Publications of Edward J. Pearce
All genres
Journal Article (67)
2021
Journal Article
592, pp. 444 - 449 (2021)
Auto-aggressive CXCR6 CD8 T cells cause liver immune pathology in NASH. Nature
Journal Article
12, 2133 (2021)
IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals. Nature Communications 2020
Journal Article
10, 21626 (2020)
MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells. Scientific Reports
Journal Article
32, pp. 981 - 995 (2020)
Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity. Cell Metabolism
Journal Article
53, pp. 641 - 657 (2020)
Osteopontin Expression Identifies a Subsetof Recruited Macrophages Distinctfrom Kupffer Cells in the Fatty Liver. Immunity
Journal Article
2, pp. 703 - 716 (2020)
Metabolic conditioning of CD8+ effector T cells for adoptive cell therapy. Nature Metabolism
Journal Article
295, pp. 54 - 67 (2020)
Cell-intrinsic metabolic regulation of mononuclear activation: Findings from the tip of the iceberg. Immunological Reviews
Journal Article
31, pp. 422 - 437 (2020)
Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function. Cell Metabolism
Journal Article
11, pp. 1 - 11 (2020)
Triacylglycerol synthesis enhances macrophage inflammatory function. Nature Communications 2019
Journal Article
30, pp. 352 - 363 (2019)
Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation. Cell Metabolism
Journal Article
20, pp. 793 - 801 (2019)
Metabolic adaptations of tissue-resident immune cells. Nature Immunology
Journal Article
27, pp. 2063 - 2074 (2019)
Acetate Promotes T Cell Effector Function during Glucose Restriction. Cell Reports
Journal Article
19, pp. 324 - 334 (2019)
Metabolic interventions in the immune response to cancer. Nature Reviews Immunology
Journal Article
20, pp. 420 - 432 (2019)
Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species-mediated DNA damage. Nature Immunology 2018
Journal Article
49, pp. 1021 - 1033 (2018)
Mitochondrial Membrane Potential Regulates Nuclear Gene Expression Macrophages Exposed to Prostaglandin. Immunity
Journal Article
9, p. 2580 (2018)
Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype. Frontiers in immunology
Journal Article
360, pp. 377 - 378 (2018)
Disrupting metabolism to treat autoimmunity: Dimethyl fumarate, a treatment ofr multiple sclerosis, inhibits Warburg metabolism. Science
Journal Article
18, pp. 81 - 82 (2018)
Immunometabolism in 2017: Driving immunity: all roads lead to metabolism. Nature Reviews Immunology 2017
Journal Article
171, pp. 385 - 397 (2017)
Mitochondrial Priming by CD28. Cell
Journal Article
25, pp. 1213 - 1215 (2017)
Treg Cells Survive and Thrive in Inhospitable Environments. Cell Metabolism
Journal Article
46, pp. 730 - 742 (2017)
MenTORing Immunity: mTOR Signaling in the Development and Function of Tissue-Resident Immune Cells. Immunity
Journal Article
356, pp. 488 - 489 (2017)
Inflammation by way of macrophage metabolism. Science 2016
Journal Article
28, pp. 408 - 416 (2016)
Metabolism and acetylation in innnate immune cell function and fate. Seminars in Immunology
Journal Article
45, pp. 817 - 830 (2016)
Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis is Essential for Macrophage Alternative Activation. Immunity
Journal Article
16, pp. 1829 - 1837 (2016)
The Transcriptional Repressor Polycomb Group Factor 6, PCGF6, Negatively Regulates Dendritic Cell Activation and Promotes Quiescence. Cell
Journal Article
166, pp. 63 - 76 (2016)
Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming. Cell
Journal Article
44, pp. 1325 - 1326 (2016)
Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function. Immunity
Journal Article
167, pp. 1708 - 1720 (2016)
The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites. Cell
Journal Article
213, pp. 15 - 23 (2016)
Immunometabolism governs dendritic cell and macrophage function. Journal of Experimental Medicine
Journal Article
213, pp. 35 - 51 (2016)
Migratory CD103+ dendritic cells suppress helminth-driven Type2 immunity through constitutive expression of IL-12. Journal of Experimental Medicine