Sarah Bowden

from Dunedin, New Zealand
IMPRS doctoral researcher since December 2020 in Walentek lab

Research interests
The Xenopus epidermis is used as a model to reveal key mechanisms of mucociliary development, regeneration, and its role in mammalian airway diseases and ciliopathies. While key transcription factors and cellular processes mediating cell type specification, differentiation, and epithelial morphology are now being revealed, there is still a large gap in understanding the relationship between signalling pathways, chromatin dynamics, and cell fate decisions of the cells during development. In my PhD project I aim to incorporate epigenetics with transcriptomics and signalling manipulations to resolve how chromatin changes over time contribute to mucociliary development and morphogenesis.
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