Simon Stitzinger

from Hanover, Germany
IMPRS doctoral researcher since January 2024 in Cissé lab

original

Research interests
Transcription of DNA into RNA lies at the heart of gene expression. This process is performed by RNA polymerase (RNAP), a molecular motor that reads the DNA template base by base and synthesizes an RNA molecule. I am following RNAPs from the formation of clusters, initiation of transcription, to active elongation, on a single molecule level. Using single molecule, super resolution imaging techniques, I am tracking RNAP molecules inside living cells, to uncover the dynamic biophysical properties of transcription, with a focus on the mechanics of elongation in vivo. In addition, I will be advancing the application of single molecule imaging and tracking with nanometer precision in living cells.
 
Go to Editor View