Max Planck Institute of Immunobiology and Epigenetics

Publications of Nina Cabezas-Wallscheid

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Journal Article (30)

2022

Journal Article

Schönberger, K.; Obier, N.; Romero-Mulero, M. C.; Cauchy, P.; Mess, J.; Pavlovich, P. V.; Zhang, Y. W.; Mitterer, M.; Rettkowski, J.; Lalioti, M.-E. et al.; Jäcklein, K.; Curtis, J. D.; Féret, B.; Sommerkamp, P.; Morganti, C.; Ito, K.; Ghyselinck, N. B.; Trompouki, E.; Büscher, J. M.; Pearce, E. L.; Cabezas-Wallscheid, N.: Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity. Cell Stem Cell 29, pp. 131 - 148 (2022)

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2021

Journal Article

Challen, G. A.; Pietras, E. M.; Cabezas-Wallscheid, N.; Signer, R. A. J.: Simplified murine multipotent progenitor isolation scheme: Establishing a consensus approach for multipotent progenitor identification. Experimental Hematology 104, pp. 55 - 63 (2021)

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Clapes, T.; Polyzou, A.; Prater, P.; Sagar; Morales-Hernández, A.; Ferrarini, M. G.; Kehrer, N.; Lefkopoulos, S.; Bergo, V.; Hummel, B. et al.; Obier, N.; Maticzka, D.; Bridgeman, A.; Herman, J. S.; Ilik, I.; Klaeylé, L.; Rehwinkel, J.; McKinney-Freeman, S.; Backofen, R.; Akhtar, A.; Cabezas-Wallscheid, N.; Sawarkar, R.; Rebollo, R.; Grün, D.; Trompouki, E.: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration. Nature Cell Biology 23, pp. 704 - 717 (2021)

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Lalioti, M.-E.; Rettkowski, J.; Cabezas-Wallscheid, N.: Avoid shocking your hematopoietic stem cells to keep them young and growing. Cell Stem Cell 28, pp. 1887 - 1889 (2021)

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Renders, S.; Svendsen, A. F.; Panten, J.; Rama, N.; Maryanovich, M.; Sommerkamp, P.; Ladel, L.; Redavid, A. R.; Gibert, B.; Lazare, S. et al.; Ducarouge, B.; Schönberger, K.; Narr, A.; Tourbez, M.; Dethmers-Ausema, B.; Zwart, E.; Hotz-Wagenblatt, A.; Zhang, D.; Korn, C.; Zeisberger, P.; Przybylla, A.; Sohn, M.; Mendez-Ferrer, S.; Heikenwälder, M.; Brune, M.; Klimmeck, D.; Bystrykh, L.; Frenette, P. S.; Mehlen, P.; de Haan, G.; Cabezas-Wallscheid, N.; Trumpp, A.: Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1. Nature Communications 12, 608 (2021)

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Sommerkamp, P.; Cabezas-Wallscheid, N.; Trumpp, A.: Alternative Polyadenylation in Stem Cell Self-Renewal and Differentiation. Trends in Molecular Medicine 27, pp. 660 - 672 (2021)

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Sommerkamp, P.; Romero-Mulero, M. C.; Narr, A.; Ladel, L.; Hustin, L.; Schönberger, K.; Renders, S.; Altamura, S.; Zeisberger, P.; Jäcklein, K. et al.; Klimmeck, D.; Rodriguez-Fraticelli, A.; Camargo, F. D.; Perié, L.; Trumpp, A.; Cabezas-Wallscheid, N.: Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells. Blood 137, pp. 3218 - 3224 (2021)

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Spiecker, L.; Witte, I.; Mehlig, J.; Shah, V.; Meyerhöfer, M.; Haehnel, P. S.; Petermann, V.; Schüler, A.; More, P.; Cabezas-Wallscheid, N. et al.; Horke, S.; Pautz, A.; Daiber, A.; Sasca, D.; Kindler, T.; Kleinert, a. H.: Deficiency of Antioxidative Paraoxonase 2 (Pon2) Leads to Increased Number of Phenotypic LT-HSCs and Disturbed Erythropoiesis. Oxidative medicine and cellular longevity, 3917028 (2021)

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Spohr, C.; Poggio, T.; Andrieux, G.; Schönberger, K.; Cabezas-Wallscheid, N.; Boerries, M.; Halbach, S.; Illert, A. L.; Brummer, T.: Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. (2021)

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Zhang, Y. W.; Mess, J.; Cabezas-Wallscheid, N.: Characterizing the In Vivo Role of Candidate Leukemia Stem Cell Genes. Methods in Molecular Biology 2185, pp. 307 - 316 (2021)

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2020

Journal Article

Carrelha, J.; Lin, D. S.; Rodriguez-Fraticelli, A. E.; Luis, T. C.; Wilkinson, A. C.; Cabezas-Wallscheid, N.; Tremblay, C. S.; Haas, S.: Single-cell lineage tracing approaches in hematology research - technical consideration. Experimental Hematology 89, pp. 26 - 36 (2020)

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Kokkaliaris, K. D.; Kunz, L.; Cabezas-Wallscheid, N.; Christodoulou, C.; Renders, S.; Camargo, F.; Trumpp, A.; Scadden, D. T.; Schroeder, T.: Adult blood stem cell localization reflects the abundance of reported bone marrow niche cell types and their combinations. Blood 136, pp. 2296 - 2307 (2020)

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Kreutmair, S.; Erlacher, M.; Andrieux, G.; Istvanffy, R.; Mueller-Rudorf, A.; Zwick, M.; Rückert, T.; Pantic, M.; Poggio, T.; Shoumariyeh, K. et al.; Mueller, T. A.; Kawaguchi, H.; Follo, M.; Klingeberg, C.; Wlodarski, M.; Baumann, I.; Pfeifer, D.; Kulinski, M.; Rudelius, M.; Lemeer, S.; Kuster, B.; Dierks, C.; Peschel, C.; Cabezas-Wallscheid, N.; Duque-Afonso, J.; Zeiser, R.; Cleary, M. L.; Schindler, D.; Schmitt-Graeff, A.; Boerries, M.; Niemeyer, C. M.; Oostendorp, R. A.; Duyster, J.; Illert, A. L.: Loss of the Fanconi anemia-associated protein NIPA causes bone marrow failure. The Journal of Clinical Investigation 130, pp. 2827 - 2844 (2020)

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Sommerkamp, P.; Altamura, S.; Renders, S.; Narr, A.; Ladel, L.; Zeisberger, P.; Eiben, P. L.; Fawaz, M.; Rieger, M. A.; Cabezas-Wallscheid, N. et al.; Trumpp, A.: Differential Alternative Polyadenylation Landscapes Mediate Hematopoietic Stem Cell Activation and Regulate Glutamine Metabolism. Cell Stem Cell 26, pp. 722 - 738 (2020)

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2019

Journal Article

Saçma, M.; Pospiech, J.; Bogeska, R.; de Back, W.; Mallm, J.-P.; Sakk, V.; Soller, K.; Marka, G.; Vollmer, A.; Karns, R. et al.; Cabezas-Wallscheid, N.; Trumpp, A.; Méndez-Ferrer, S.; Milsom, M. D.; Mulaw, M. A.; &, H. G.; Florian, M. C.: Haematopoietic stem cells in perisinusoidal niches are protected from ageing. Nature Cell Biology 21, pp. 1309 - 1320 (2019)

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Sommerkamp, P.; Renders, S.; Ladel, L.; Hotz-Wagenblatt, A.; Schönberger, K.; Zeisberger, P.; Przybylla, A.; Sohn, M.; Zhou, Y.; Klibanski, A. et al.; Cabezas-Wallscheid, N.; Trumpp, A.: The long non-coding RNA Meg3 is dispensable for hematopoietic stem cells. Scientific Reports 9, p. 2110 (2019)

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2018

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Florian, M. C.; Klose, M.; Sacma, M.; Jablanovic, J.; Knudson, L.; Nattamai, K. J.; Marka, G.; Vollmer, A.; Soller, K.; Sakk, V. et al.; Cabezas-Wallscheid, N.; Zheng, Y.; Mulaw, M. A.; Glauche, I.; Geiger, H.: Aging alters the epigenetic asymmetry of HSC division. PLoS Biology 16, p. e2003389 (2018)

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Giladi, A.; Paul, F.; Herzog, Y.; Lubling, Y.; Weiner, A.; Yofe, I.; Jaitin, D.; Cabezas-Wallscheid, N.; Dress, R.; Ginhoux, F. et al.; Trumpp, A.; Tanay, A.; Amit, I.: Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis. Nature Cell Biology 20, pp. 836 - 846 (2018)

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2017

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Cabezas-Wallscheid, N.; Buettner, F.; Sommerkamp, P.; Klimmeck, D.; Ladel, L.; Thalheimer, F. B.; Pastor-Flores, D.; Roma, L. P.; Renders, S.; Zeisberger, P. et al.; Przybylla, A.; Schönberger, K.; Scognamiglio, R.; Altamura, S.; Florian, C. M.; Fawaz, M.; Vonficht, D.; Tesio, M.; Collier, P.; Pavlinic, D.; Geiger, H.; Schroeder, T.; Benes, V.; Dick, T. P.; Rieger, M. A.; Stegle, O.; Trumpp, A.: Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy. Cell 169, pp. 807 - 823 (2017)

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Schönberger, K.; Cabezas-Wallscheid, N.: Vitamin C: C-ing a New Way to Fight Leukemia. Cell Stem Cell 21, pp. 561 - 563 (2017)

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2016

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Cabezas-Wallscheid, N.; Trumpp, A.: Potency finds its niches. Science 351, pp. 126 - 127 (2016)

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Scognamiglio, R.; Cabezas-Wallscheid, N.; Thier, M. C.; Altamura, S.; Reyes, A.; Prendergast, Á. M.; Baumgärtner, D.; Carnevalli, L. S.; Atzberger, A.; Haas, S. et al.; von Paleske, L.; Boroviak, T.; Wörsdörfer, P.; Essers, M. A.G.; Kloz, U.; Eisenman, R. N.; Edenhofer, F.; Bertone, P.; Trumpp, A.: Myc depletion induces a pluripotent dormant State mimicking diapause. Cell 164, pp. 126 - 127 (2016)

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2014

Journal Article

Cabezas-Wallscheid, N.; Klimmeck, D.; Hansson, J.; Lipka, D. B.; Reyes, A.; Wang, Q.; Weichenhan, D.; Lier, A.; von Paleske, L.; Renders, S. et al.; Wünsche, P.; Zeisberger, P.; Brocks, D.; Gu, L.; Herrmann, C.; Haas, S.; Essers, M. A.G.; Brors, B.; Trumpp, A.: Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis. Cell Stem Cell 15, pp. 507 - 522 (2014)

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Carnevalli, L. S.; Scognamiglio, R.; Cabezas-Wallscheid, N.; Rahmig, S.; Laurenti, E.; Masuda, K.; Jöckel, L.; Kuck, A.; Sujer, S.; Polykratis, A. et al.; Erlacher, M.; Pasparakis, M.; Essers, M. A.G.; Trumpp, A.: Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking Granzyme B. Journal of Experimental Medicine 211, pp. 769 - 779 (2014)

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Klimmeck, D.; Cabezas-Wallscheid, N.; Reyes, A.; von Paleske, L.; Renders, S.; Hansson, J.; Krijgsveld, J.; Huber, W.; Trumpp, A.: Transcriptome-wide profiling and posttranscriptional analysis of hematopoietic stem/progenitor cell differentiation toward myeloid commitment. Stem Cell Reports 11, pp. 858 - 875 (2014)

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Lipka, D. B.; Wang, Q.; Cabezas-Wallscheid, N.; Klimmeck, D.; Weichenhan, D.; Herrmann, C.; Lier, A.; Brocks, D.; von Paleske, L.; Renders, S. et al.; Wünsche, P.; Zeisberger, P.; Gu, L.; Haas, S.; Essers, M. A.; Brors, B.; Eils, R.; Trumpp, A.; Milsom , M. D.; Plass, C.: Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing. Cell Cycle 13, pp. 3476 - 3487 (2014)

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2013

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Cabezas-Wallscheid, N.; Eichwald, V.; de Graaf, J.; Löwer, M.; Lehr, H.; Kreft, A.; Eshkind, L.; Hildebrandt, A.; Abassi, Y.; Heck, R. et al.; Dehof, A. K.; Ohngemach, S.; Sprengel, R.; Wörtge, S.; Schmitt, S.; Lotz, J.; Meyer, C.; Kindler, T.; Zhang, D.; Kaina, B.; Castle, J. C.; Trumpp, A.; Sahin, U.; Bockamp, E.: Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model. EMBO molecular Medicine 5 (12), pp. 1804 - 1820 (2013)

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2010

Journal Article

Wortge, S.; Eshkind, L.; Cabezas-Wallscheid, N.; Lakaye, B.; Kim, J.-H.; Heck, R.; Abassi, Y.; Diken, M.; Sprengel, R.; Bockamp, E.: Tetracycline-controlled transgene activation using the ROSA26-iM2-GFP knock-in mouse strain permits GFP monitoring of DOX-regulated transgene-expression. BMC Developmental Biology 10, 95, pp. 1 - 13 (2010)

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2009

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Bockamp, E.; Antunes, C.; Liebner, S.; Schmitt, S.; Cabezas-Wallscheid, N.; Heck, R.; Ohnngemach, S.; Oesch-Bartlomowicz, B.; Rickert, C.; Sanchez, M. J. et al.; Hengstler, J.; Kaina, B.; Wilson, A.; Trumpp, A.; Eshkind, L.: In vivo fate mapping with SCL regulatory elements identifies elements identifies progenitors for primitive and definitive hematopoiesis in mice. Mechanisms of Development 126, pp. 863 - 872 (2009)

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2007

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Bockamp, E.; Christel, C.; Hameyer, D.; Khobta, A.; Maringer, M.; Reis, M.; Heck, R.; Cabezas-Wallscheid, N.; Epe, B.; Oesch‐Bartlomowicz, B. et al.; Kaina, B.; Schmitt, S.; Eshkind, L.: Generation and characterization of tTS-H4: a novel transcriptional repressor that is compatible with the reverse tetracycline-controlled TET-ON system. The Journal of Gene Medicine 9, pp. 308 - 318 (2007)

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