Publications of Gerhard Mittler

Journal Article (34)

2021
Journal Article
Montavon, T.; Shukeir, N.; Erikson, G.; Engist, B.; Onishi-Seebacher, M.; Ryan, D.; Musa, Y.; Mittler, G.; Meyer, A. G.; Genoud, C. et al.; Jenuwein, T.: Complete loss of H3K9 methylation dissolves mouse heterochromatin organization. Nature Communications 12, 4359 (2021) (2021)
Journal Article
Duda, K. J.; Ching, R. W.; Jerabek, L.; Shukeir, N.; Erikson, G.; Engist, B.; Onishi-Seebacher, M.; Perrera, V.; Richter, F.; Mittler, G. et al.; Fritz, K.; Helm, M.; Knuckles, P.; Bühler, M.; Jenuwein, T.: m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA:DNA hybrid formation in mouse heterochromatin. Nucleic Acids Research (London) 49, pp. 5568 - 5587 (2021)
Journal Article
Akerman, I.; Maestro, M. A.; Franco, E. D.; Grau, V.; Flanagan, S.; García-Hurtado, J.; Mittler, G.; Ravassard, P.; Piemonti, L.; Ellard, S. et al.; Hattersley, A. T.; Ferrer, J.: Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene. Cell Reports 35 (2021)
Journal Article
Stanczak, M. A.; Sanin, P. D. E.; Apostolova, P.; Nerz, G.; Lampaki, D.; Hofmann, M.; Steinmann, D.; Krohn-Grimberghe, M.; Thimme, R.; Mittler, G. et al.; Waller, C. F.; Pearce, E. J.; Pearce, E. L.: IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals. Nature Communications 12, p. 2133 (2021)
Journal Article
Kelly, B.; Carrizo, G. E.; Edwards-Hicks, J.; Sanin, P. D. E.; Stanczak, M. A.; Priesnitz, C.; Flachsmann, L. J.; Jonathan, D. C.; Mittler, G.; Musa, Y. et al.; Becker, T.; Büscher, J. M.; Pearce, E. L.: Sulfur sequestration promotes multicellularity during nutrient limitation. Nature 591, pp. 471 - 476 (2021)
2020
Journal Article
Wang, Y.; Zolotarev, N.; Yang, C.-Y.; Rambold, A.; Mittler, G.; Grosschedl, R.: A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin. Immunity 53, pp. 1151 - 1167 (2020)
Journal Article
Carrasco, J.; Rauer, M.; Hummel, B.; Grzejda, D.; Alfonso-Gonzalez, C.; Lee, Y.; Wang, Q.; Puchalska, M.; Mittler, G.; Hilgers, V.: ELAV and FNE Determine Neuronal Transcript Signatures through EXon-Activated Rescue. Molecular Cell 80, pp. 156 - 163 (2020)
2019
Journal Article
Karoutas, A.; Szymanski, W.; Rausch, T.; Guhathakurta, S.; Rog-Zielinska, E. A.; Peyronnet, R.; Seyfferth, J.; Chen, H.-R.; de Leeuw, R.; Herquel, B. et al.; Kimura, H.; Mittler, G.; Kohl, P.; Medalia, O.; Korbel, J. O.; Akhtar, A.: The NSL complex maintains nuclear architecture stability via lamin A/C acetylation. Nature Cell Biology 21, pp. 1248 - 1260 (2019)
Journal Article
Panhale, A.; Richter , F. M.; Ramírez, F.; Shvedunova, M.; Manke, T.; Mittler, G.; Akhtar, A.: CAPRI enables comparison of evolutionary conserved RNA interacting regions. Nature Communications 10, 2682 (2019) (2019)
Journal Article
Puleston, D. J.; Buck, M. D.; Geltink, R. I. K.; Kyle, R. L.; Caputa, G.; O’Sullivan, D.; Cameron, A. M.; Castoldi, A.; Musa, Y.; Kabat, A. M. et al.; Zhang, Y.; Flachsmann, L. J.; Field, C. S.; Patterson, A. E.; Scherer, S.; Alfei, F.; Baixauli, F.; Austin, S. K.; Kelly, B.; Matsushita, M.; Curtis, J. D.; Grzes, K. M.; Villa, M.; Corrado, M.; Sanin, D. E.; Qiu, J.; Pällman, N.; Paz, K.; Maccari, M. E.; Blazar, B. R.; Mittler, G.; Büscher, J.; Zehn, D.; Rospert, S.; Pearce, E. J.; Balabanov, S.; Pearce, E. L.: Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation. Cell Metabolism 30, pp. 1 - 12 (2019)
2018
Journal Article
Sanin, D. E.; Matsushita, M.; Klein-Geltink, R.; Grzes, K.; van Bakker, N. T.; Corrado, M.; Kabat, A.; Buck, M. D.; Qiu, J.; Lawless, S. J. et al.; Cameron, A.; Villa, M.; Baixauli Celda, F.; Patterson, A. E.; Hässler, F.; Curtis, J. D.; O’Neill, C. M.; O'Sullivan, D.; Wu, D.; Mittler, G.; Huang, S. C.-C.; Pearce, E. L.; Pearce, E. J.: Mitochondrial Membrane Potential Regulates Nuclear Gene Expression Macrophages Exposed to Prostaglandin. Immunity 49, pp. 1021 - 1033 (2018)
Journal Article
Ramos Pittol, J. M.; Oruba, A.; Mittler, G.; Saccani , S.; van Essen, D.: Zbrv7a is a transducer for the control of promoter accessibility by NF-kappa B and multiple other transcription factors. PLoS Biology 16, p. e2004526 (2018)
Journal Article
Giaimo, B. D.; Ferrante, F.; Vallejo, D. M.; Hein, K.; Gutierrez-Perez, I.; Nist, A.; Stiewe, T.; Mittler, G.; Herold, S.; Zimmermann, T. et al.; Bartkuhn, M.; Schwarz, P.; Oswald, F.; Dominguez, M.; Borggrefe, T.: Histone variant H2A.Z deposition and acetlyation directs the canonical Notch signaling response. Nucleic Acids Research (London) 46, pp. 8197 - 8215 (2018)
Journal Article
Musa, Y. R.; Boller, S.; Puchalska, M.; Grosschedl, R.; Mittler, G.: Comprehensive Proteomic Investigation of Ebf1 Heterozygosity in Pro-B Lymphocytes Ulilizing Data Independent Acquisition. Journal of Proteome Research 17, pp. 76 - 85 (2018)
2017
Journal Article
Aktas, T.; Ilik, I. A.; Maticzka, D.; Bhardwaj, V.; Rodrigues , C. P.; Mittler, G.; Manke, T.; Backofen, R.; Akhtar, A.: DHX9 Suppresses RNA processing defects originating from the Alu invasion of the human genome. Nature 544, pp. 115 - 119 (2017)
2016
Journal Article
Yang, C.-Y.; Ramamoorthy, S.; Boller, S.; Rosenbaum, M.; Gil, A. R.; Mittler, G.; Imai, Y.; Kuba, K.; Grosschedl, R.: Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis. Genes and Development 30, pp. 2310 - 2324 (2016)
Journal Article
Chlamydas, S.; Holz, H.; Samata, M.; Chelmicki, T.; Georgiev, P.; Pelechano, V.; Dündar, F.; Dasmeh, P.; Mittler, G.; Tavares Cadete, F. et al.; Ramirez, F.; Conrad, T.; Wei, W.; Raja, S.; Manke, T.; Luscombe, N. M.; Steinmetz, L. M.; Akhtar, A.: Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation. Nature Structural and Molecular Biology 23, pp. 580 - 589 (2016)
Journal Article
Trung, N. T.; Kremer, E.; Mittler, G.: Biochemical and cellular characterization of transcription factors binding to the hyperconserved core promoter-associated M4 motif. BMC Genomics 17, p. 693 (2016)
2015
Journal Article
Cohen, I.; Rider, P.; Vornov, E.; Tomas, M.; Tudor, C.; Wegner, M.; Brondani, L.; Freudenberg, M.; Mittler, G.; Elisa, F.-M. et al.; Dinarello, C. A.; Apte, R. N.; Schneider, R.: IL-1α is a DNA damage sensor linking genetoxic stress signaling to sterile inflammation and innate immunity. Scientific Reports 5, pp. 1 - 11 (2015)
Journal Article
Prasad, S.; Gaedicke, S.; Machein, M.; Mittler, G.; Braun , F.; Hettich, M.; Firat, E.; Klingner, K.; Schüler, J.; Wider, D. et al.; Wäsch, R. M.; Herold-Mende, C.; Elsässer-Beile, U.; Niedermann, G.: Effective Eradication of Gliioblastoma Stem Cells by Local Application of AC133/CD133-Specific T-cell Engaging Antibody and CD8 T Cells. Cancer research: an official organ of the American Association for Cancer Research 75, pp. 2166 - 2176 (2015)
Journal Article
Hein, K.; Mittler, G.; Cizelsky, W.; Kühl, M.; Ferrante , F.; Liefke, R.; Berger, I. M.; Just, S.; Sträng, J. E.; Kestler, H. A. et al.; Oswald, F.; Borggrefe, T.: Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response. ScienceSignaling 8, pp. 1 - 12 (2015)
2014
Journal Article
Albert, T. K.; Rigault, C.; Eickhoff, J.; Baumgart, K.; Antrecht, C.; Klebl, B.; Mittler, G.; Meisterernst, M.: Characterization of molecular and cellular functions of the cyclin-dependent kinase CDK9 using a novel specific inhibitor. British Journal of Pharmacology 171, pp. 55 - 68 (2014)
Journal Article
Biterge, B.; Richter, F.; Mittler, G.; Schneider, R.: Methylation of histone H4 at aspartate 24 by Protein L-isoaspartate O-methyltransferase (PCMT1) links histone modification with protein homeostasis. Scientific Reports 4, p. 6674 - 6674 (2014)
Journal Article
Di Cerbo, V.; Mohn, F.; Ryan, D. P.; Montellier, E.; Kacem, S.; Tropberger, P.; Kallis, E.; Holzner, M.; Hoerner, L.; Feldmann, A. et al.; Richter, F. M.; Bannister, A. J.; Mittler, G.; Michaelis, J.; Khochbin, S.; Feil, R.; Schuebeler, D.; Owen-Hughes, T.; Daujat, S.; Schneider, R.: Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription. eLife 3, pp. 1 - 23 (2014)
Journal Article
Tat Trung, N.; Engelke, R.; Mittler, G.: SILAC-Based Quantitative Proteomics Approach to Identify Transcription Factors Interacting with a Novel Cis-Regulatory Element. Proteomics & Bioinformatics 7, pp. 082 - 087 (2014)
2013
Journal Article
Klug, H.; Xaver, M.; Chaugule, V. K.; Koidl, S.; Mittler, G.; Klein, F.; Pichler, A.: Ubc9 Sumoylation Controls SUMO Chain Formation and Meiotic Synapsis in Saccharomyces cerevisiae. Molecular Cell 50, pp. 625 - 636 (2013)
Journal Article
Sané, S.; Jolivalt, C.; Mittler, G.; Nielsen, P. J.; Rubenwolf, S.; Zengerle, R.; Kerzenmacher, S.: Overcoming Bottlenecks of Enzymatic Biofuel Cell Cathodes: Crude Fungal Culture Supernatant Can Help to Extend Lifetime and Reduce Cost. ChemSusChem 6, pp. 1209 - 1215 (2013)
2012
Journal Article
Pinheiro, I.; Margueron, R.; Shukeir, N.; Eisold, M.; Fritzsch, C.; Richter, F. M.; Mittler, G.; Genoud, C.; Goyama, S.; Kurokawa, M. et al.; Son, J.; Reinberg, D.; Lachner, M.; Jenuwein, T.: Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity. Cell 150, pp. 948 - 960 (2012)
2011
Journal Article
Waldmann, T.; Izzo, A.; Kamieniarz, K.; Richter, F.; Vogler, C.; Sarg, B.; Lindner, H.; Young, N. L.; Mittler, G.; Garcia, B. A. et al.; Schneider, R.: Methylation of H2AR29 is a novel repressive PRMT6 target. Epigenetics & Chromatin 4, pp. 1 - 10 (2011)
2010
Journal Article
Flach, H.; Rosenbaum, M.; Duchniewicz, M.; Kim, S.; Zhang, S. L.; Cahalan, M. D.; Mittler, G.; Grosschedl, R.: Mzb1 Protein Regulates Calcium Homeostasis, Antibody Secretion, and Integrin Activation in Innate-like B Cells. Immunity 33, pp. 723 - 735 (2010)
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