Publications of Michael Reth

Journal Article (105)

2016
Journal Article
Yang, J.; Reth, M.: Receptor Dissociation and B-Cell Activation. Current Topics in Microbiology and Immunology 393, pp. 27 - 44 (2016)
2015
Journal Article
Maity, P. C.; Blount, A.; Jumaa, H.; Ronneberger, O.; Lillemeier, B. F.; Reth, M.: B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation. Science Signaling 8, p. ra93 (2015)
Journal Article
Fiala, G. J.; Janowska, I.; Prutek, F.; Hobeika, E.; Satapathy, A.; Sprenger, A.; Plum, T.; Seidl, M.; Dengjel, J.; Reth, M. et al.; Cesca, F.; Brummer, T.; Minguet, S.; Schamel, W. W. A.: Kidins220/ARMS binds to the B cell antigen recptor and regulates B cell development and activation. The Journal of Experimental Medicine 212 (10), pp. 1693 - 1708 (2015)
Journal Article
Hüttle, S.; Kläsener, K.; Schweizer, M.; Schneppenheim, J.; Oberg, H.-H.; Kabelitz, D.; Reth, M.; Saftig, P.; Schröder, B.: Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical for B Cell Receptor Signaling in Transitional B Cells. The Journal of Immunology 195, pp. 1548 - 1563 (2015)
Journal Article
Chen, Z.; Shojaee, S.; Buchner, M.; Geng, H.; Lee, J. W.; Klemm, L.; Titz, B.; Graeber, T.; Park, E.; Tan, Y. X. et al.; Satterthwaite, A.; Paietta, E.; Hunger, S. P.; Willman, C. L.; Melnick, A.; Loh, M. L.; Jung, J. U.; Coligan, J. E.; Bolland, S.; Mak, T. W.; Limnander, A.; Jumaa, H.; Reth, M.; Weiss, A.; Lowell, C. A.; Müschen, M.: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature 521, pp. 357 - 361 (2015)
Journal Article
Übelhart, R.; Hug, E.; Bach, M. P.; Wossning, T.; Dühren-von Minden, M.; Horn, A. H.C.; Tsiantoulas, D.; Kometani, K.; Kurosaki, T.; Binder, C. J. et al.; Sticht, H.; Nitschke, L.; Reth, M.; Jumaa, H.: Responsiveness of B cell is regulated by hinge region of IgD. Nature Immunology 16, pp. 534 - 543 (2015)
Journal Article
Alarcón, B.; Reth, M.; Schamel, W. W.: Preface to special issue on nanoscale membrane organisations. Biochimica et Biophysica Acta-Molecular Cell Research 1853, pp. 765 - 766 (2015)
Journal Article
Hobeika, E.; Zerdoun Levit, E.; Anastasopoulou, V.; Pohlmeyer, R.; Altmeier, S.; Alsedeq, A.; Dobenecker, M.-W.; Pelanda, R.; Reth, M.: CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk. The EMBO Journal 34, pp. 925 - 939 (2015)
Journal Article
Maity, P. C.; Yang, J.; Klaesener, K.; Reth, M.: The nanoscale organization of the B lymphocyte membrane. Biochimica et Biophysica Acta-Molecular Cell Research 1853, pp. 830 - 840 (2015)
Journal Article
Thien, A.; Prentzell, M. T.; Holzwarth, B.; Kläsener, K.; Kuper, I.; Boehlke, C.; Sonntag, A. G.; Ruf, S.; Maerz, L.; Nitschke, R. et al.; Grellscheid, S.-N.; Reth, M.; Walz, G.; Baumeister, R.; Neumann-Haefelin, E.; Thedieck, K.: TSC1 Activates TGF-β-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition. Developmental Cell 32, pp. 617 - 630 (2015)
Journal Article
Busch, K.; Klapproth, K.; Barile, M.; Flossdorf, M.; Holland-Letz, T.; Schlenner, S. M.; Reth, M.; Höfer, T.; Rodewald, H.-R.: Fundamental properties of unperturbed haematopoiesis from stem cell in vivo. Nature 518, pp. 542 - 546 (2015)
Journal Article
Königsberger, S.; Weis, V.; Prodöhl, J.; Stehling, M.; Hobeika, E.; Reth, M.; Kiefer, F.: Suboptimal B-cell antigen receptor signaling activity in vivo elicits germina center counterselection mechanisms. European Journal of Immunology 45, pp. 603 - 611 (2015)
2014
Journal Article
Baracho, G. V.; Cato, M. H.; Zhu, Z.; Jaren, O. R.; Hobeika, E.; Reth, M.; Rickert, R. C.: PDK1 regulates B cell differentiation and homeostasis. Proceedings of the National Academy of Sciences, USA, pp. 9573 - 9578 (2014)
Journal Article
Alsadeq, A.; Hobeika, E.; Medgyesi, D.; Kläsener, K.; Reth, M.: The Role of the Syk/Shp-1 Kinase-Phosphatase Equilibrium in B Cell Development and Signaling. The Journal of Immunology 193, pp. 268 - 276 (2014)
Journal Article
Grötsch, B.; Brachs, S.; Lang, C.; Luther, J.; Derer, A.; Schlötzer-Schrehardt, U.; Bozec, A.; Fillatreau, S.; Berberich, I.; Hobeika, E. et al.; Reth, M.; Wagner, E. F.; Schett, G.; Mielenz, D.; David, J.-P.: The AP-1 transcription factor Fra1 ihhibits follicular B cell differentiation into plasma cells. The Journal of Experimental Medicine 211, pp. 2199 - 2212 (2014)
Journal Article
Hug, E.; Hobeika, E.; Reth, M.; Jumaa, H.: Inducible expression of hyperactive Syk in B cells activates Blimp-1-dependent terminal differentiation. Oncogene 33, pp. 3730 - 3741 (2014)
Journal Article
Hutzler, S.; Özgör, L.; Naito-Matsui, Y.; Kläsener, K.; Winkler, T. H.; Reth, M.; Nitschke, L.: The Ligand-Binding Domain of Siglec-G Is Crucial for Its Selective Inhibitory Function on B1 Cells. The Journal of Immunology 192, pp. 5406 - 5414 (2014)
Journal Article
Klasen, C.; Ohl, K.; Sternkopf, M.; Shachar, I.; Schmitz, C.; Heussen, N.; Hobeika, E.; Levit-Zerdoun, E.; Tenbrock, K.; Reth, M. et al.; Bernhagen, J.; El Bounkari, O.: MIF Promotes B Cell Chemotaxis through the Receptors CXCR4 and CD74 and ZAP-70 Signaling. The Journal of Immunology 192, pp. 5273 - 5284 (2014)
Journal Article
Kläsener, K.; Maity, P. C.; Hobeika, E.; Yang, J.; Reth, M.: B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk. eLife 3, pp. 1 - 17 (2014)
Journal Article
Königsberger, S.; Weis, V.; Prodöhl, J.; Stehling, M.; Hobeika, E.; Reth, M.; Kiefer, F.: Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms. European Journal of Immunology 45, pp. 603 - 611 (2014)
Journal Article
Maity, P. C.; Yang, J.; Klaesener, K.; Reth, M.: The nanoscale organization of the B lymphocyte membrane. Biochemica et Biophiysica Acta 1853, pp. 830 - 840 (2014)
Journal Article
Medgyesi, D.; Hobeika, E.; Biesen, R.; Kollert, F.; Taddeo, A.; Voll, R. E.; Hiepe, F.; Reth, M.: The protein tyrosine phsphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity. Journal of Experimental Medicine 211, pp. 427 - 440 (2014)
Journal Article
Medgyesi, D.; Hobeika, E.; Biesen, R.; Kollert, F.; Taddeo, A.; Voll, R. E.; Hiepe, F.; Reth, M.: The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling an controls B cell autoimmunity. The Journal of Experimental Medicine 211, pp. 427 - 440 (2014)
Journal Article
Reth, M.: Antigen Receptors Tail Clue. The Journal of Immunology 192, pp. 4015 - 4016 (2014)
Journal Article
Reth, M.; Nielsen, P.: Signaling Circuits in Early B-Cell Development. Advances in Immunology 122, pp. 129 - 175 (2014)
Journal Article
Umiker, B. R.; McDonald, G.; Larbi, A.; Medina, C. O.; Hobeika, E.; Reth, M.; Imanishi-Kari, T.: Production of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE. European Journal of Immunology 44, pp. 3093 - 3108 (2014)
2013
Journal Article
Thedieck, K.; Holzwarth, B.; Prentzell, M. T.; Boehlke, C.; Kläsener, K.; Ruf, S.; Sonntag, A. G.; Maerz, L.; Sushma-Nagaraja, G.; Kremmer, E. et al.; Nitschke, R.; Kuehn, E. W.; Jonker, J. W.; Groen, A. K.; Reth, M.; Hall, M. N.; Baumeister, R.: Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells. Cell 154, pp. 859 - 874 (2013)
Journal Article
Müller, J.; Obermeier, I.; Wöhner, M.; Brandl, C.; Mrotzek, S.; Angermüller, S.; Maity, P. C.; Reth, M.; Nitschke, L.: CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling. Proceedings of the National Academy of Sciences Uzs.A. 110, pp. 12402 - 12407 (2013)
Journal Article
Kundu, K.; Costa, F.; Huber, M.; Reth, M.; Backofen, R.: Semi-Supervised Prediction of SH2-Peptide Interactions from Imbalanced High-Throughput Data. PLoS ONE 8, p. e62372 - e62372 (2013)
Journal Article
Zietra, N.; Lyszkiewicz, M.; Puchalka, J.; Pei, G.; Gutierrez, M. G.; Lienenklaus, S.; Hobeika, E.; Reth, M.; Martins dos Santos, V. A. P.; Krueger, A. et al.; Weiss, S.: Immunoglobulins drive terminal maturation of splenic dendritic cells. Proceedings of the National Academy of Sciences Uzs.A. 110, pp. 2282 - 2287 (2013)
Go to Editor View