Publications (2016-2009)
- Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function.
Andreani V, Ramamoorthy S, Pandey A, Lupar E, Nutt SL, Lämmermann T, Grosschedl R.
Proceedings of the National academy of Sciences USA (PNAS), 115(41), E9630-E9639, 2018 Oct 9.
doi: 10.1073/pnas.1809739115 - Satb2 Is Required for the Development of a Spinal Exteroceptive Microcircuit that Modulates Limb Position.
Hilde KL, Levine AJ, Hinckley CA, Hayashi M, Montgomery JM, Gullo M, Driscoll SP, Grosschedl R, Kohwi Y, Kohwi-Shigematsu T, Pfaff SL.
Neuron. 2016 Jul 27. pii: S0896-6273(16)30365-8. doi: 10.1016/j.neuron.2016.07.014. [Epub ahead of print] - Pioneering Activity of the C-Terminal Domain of EBF1 Shapes the Chromatin Landscape for B Cell Programming.
Boller S, Ramamoorthy S, Akbas D, Nechanitzky R, Burger L, Murr R, Schübeler D, Grosschedl R.
Immunity. 2016 Mar 15;44(3):527-41. doi: 10.1016/j.immuni.2016.02.021. - SUMOylation Blocks the Ubiquitin-Mediated Degradation of the Nephronophthisis Gene Product Glis2/NPHP7.
Ramachandran H, Herfurth K, Grosschedl R, Schäfer T, Walz G. (2015)
PLoS One. 2015 Jun 17;10(6):e0130275. doi: 10.1371/journal.pone.0130275. - The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function.
Boller S, Grosschedl R. (2014)
Immunol Rev. 2014 Sep;261(1):102-15. doi: 10.1111/imr.12206. - Satb2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex.
Leone DP, Heavner WE, Ferenczi EA, Dobreva G, Huguenard JR, Grosschedl R, McConnell SK. (2014)
Cereb Cortex. 2014 Jul 17. pii: bhu156. - MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress.
Rosenbaum M, Andreani V, Kapoor T, Herp S, Flach H, Duchniewicz M, Grosschedl R. (2014)
Genes Dev. 2014 Jun 1;28(11):1165-78. doi: 10.1101/gad.240762.114. - Establishment and Maintenance of B Cell Identity.
Grosschedl R. (2014)
Cold Spring Harb Symp Quant Biol. 2014 Apr 14. [Epub ahead of print] - Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma.
Okosun J, Bödör C, Wang J, Araf S, Yang CY, Pan C, Boller S, Cittaro D, Bozek M, Iqbal S, Matthews J, Wrench D, Marzec J, Tawana K, Popov N, O'Riain C, O'Shea D, Carlotti E, Davies A, Lawrie CH, Matolcsy A, Calaminici M, Norton A, Byers RJ, Mein C, Stupka E, Lister TA, Lenz G, Montoto S, Gribben JG, Fan Y, Grosschedl R, Chelala C, Fitzgibbon (2014)
J. Nat Genet. 2014 Feb;46(2):176-81. doi: 10.1038/ng.2856. - Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells.
Nechanitzky R, Akbas D, Scherer S, Györy I, Hoyler T, Ramamoorthy S, Diefenbach A, Grosschedl R. (2013)
Nat Immunol. 2013 Aug;14(8):867-75. doi: 10.1038/ni.2641. Epub 2013 Jun 30. - Sensory map transfer to the neocortex relies on pretarget ordering of thalamic axons.
Lokmane L, Proville R, Narboux-Nême N, Györy I, Keita M, Mailhes C, Léna C, Gaspar P, Grosschedl R, Garel S. (2013)
Curr Biol. 2013 May 6;23(9):810-6. doi: 10.1016/j.cub.2013.03.062. Epub 2013 Apr 25. - The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner.
Zee T, Boller S, Györy I, Makinistoglu MP, Tuckermann JP, Grosschedl R, Karsenty G. (2013)
FEBS Lett. 2013 Mar 18;587(6):711-6. doi: 10.1016/j.febslet.2013.01.049. Epub 2013 Feb 5 - A network of genetic repression and derepression specifies projection fates in the developing neocortex.
Srinivasan K, Leone DP, Bateson RK, Dobreva G, Kohwi Y, Kohwi-Shigematsu T, Grosschedl R, McConnell SK (2012)
Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19071-8 - Satb1 and Satb2 are dispensable for X chromosome inactivation in mice.
Nechanitzky R, Dávila A, Savarese F, Fietze S, Grosschedl R. (2012)
Dev Cell. 2012 Oct 16;23(4):866-71 - Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis.
Skokowa J, Klimiankou M, Klimenkova O, Lan D, Gupta K, Hussein K, Carrizosa E, Kusnetsova I, Li Z, Sustmann C, Ganser A, Zeidler C, Kreipe HH, Burkhardt J, Grosschedl R, Welte K. (2012)
Nat Med. 2012 Oct;18(10):1550-9 - miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2.
Wei J, Shi Y, Zheng L, Zhou B, Inose H, Wang J, Guo XE, Grosschedl R, Karsenty G. (2012)
J Cell Biol. 2012 May 14;197(4):509-21 - Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells.
Györy, I., Boller, S., Nechanitzky, R., Mandel, E., Pott, S., Liu, E. and Grosschedl, R. (2012)
Genes Dev. 26, 668-682 - Roles of SATB2 in osteogenic differentiation and bone regeneration.
Zhang J, Tu Q, Grosschedl R, Kim MS, Griffin T, Drissi H, Yang P, Chen J. (2011)
Tissue Eng Part A. 2011 Jul;17(13-14):1767-76. doi: 10.1089/ten.TEA.2010.0503. Epub 2011 Apr 21. - Mzb1 protein regulates calcium homeostasis, antibody secretion, and integrin activation in innate-like B cells.
Flach, H., Rosenbaum, M., Duchniewicz, M., Kim, S., Zhang, S.L., Cahalan, M.D., Mittler, G., Grosschedl, R. (2010)
Immunity 33, 723-735 - Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner.
Kieslinger, M., Hiechinger, S., Dobreva, G., Consalez, G.G., Grosschedl, R. (2010)
Cell Stem Cell. 7, 496-507 - Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins.
Treiber, N., Treiber, T., Zocher, G., Grosschedl, R. (2010)
Genes Dev. 24, 2270-2275 - Memories of lost enhancers.
Sen, R. and Grosschedl, R. (2010)
Genes Dev. 2, 973-979 - Early B Cell Factor 1 Regulates B Cell Gene Networks by Activation, Repression, and Transcription- Independent Poising of Chromatin.
Treiber, T., Mandel, E.M., Pott, S., Györy, I., Firner, S., Liu, E.T. and Grosschedl, R. (2010)
Immunity 32, 714-725 - Transcription control of early B cell differentiation.
Mandel, E.M. and Grosschedl, R. (2010)
Curr Opin Immunol. 22, 161-167 - Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression.
Savarese, F., Dávila, A., Nechanitzky, R., De La Rosa-Velazquez, I., Pereira, C.F., Engelke, R., Takahashi, K., Jenuwein, T., Kohwi-Shigematsu, T., Fisher, A.G. and Grosschedl, R. (2009)
Genes Dev. 23, 2625-2638
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