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Journal Article (12)

  1. 2020
    Journal Article
    Samata, M.; Alexia, A.; Richard, G.; Georgiev, P.; Nuebler, J.; Kulkarni, T.; Renschler, G. V.; Basilicata, M. F.; Zenk, F. L.; Shvedunova, M. et al.; Semplicio, G.; Mirny, L.; Iovino, N.; Akhtar, A.: Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is Instructive for Future Gene Activation. Cell 182, pp. 1 - 18 (2020)
  2. 2019
    Journal Article
    Lam, K.-C.; Chung, H.-R.; Semplicio, G.; Iyer, S. S.; Gaub, A.; Bhardwaj, V.; Holz, H.; Georgiev, P.; Akhtar, A.: The NSL complex-mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise. Genes and Development 33, pp. 453 - 465 (2019)
  3. 2017
    Journal Article
    Ilik, I. A.; Maticzka, D.; Georgiev, P.; Gutierrez, N. M.; Backofen, R.; Akhtar, A.: A mutually exclusive stem-loop arrangement in roX2 RNA is essential for X-chromosome regulation in Drosophila. Genes and Development, pp. 1973 - 1987 (2017)
  4. 2016
    Journal Article
    Quinn, J. J.; Zhang, Q. C.; Georgiev, P.; Ilik, I. A.; Akhtar, A.; Chang, H. Y.: Rapid evolutionary turnover underlies conserved lncRNA-genome interactions. Genes and Development 30, pp. 191 - 207 (2016)
  5. Journal Article
    Chlamydas, S.; Holz, H.; Samata, M.; Chelmicki, T.; Georgiev, P.; Pelechano, V.; Dündar, F.; Dasmeh, P.; Mittler, G.; Tavares Cadete, F. et al.; Ramirez, F.; Conrad, T.; Wei, W.; Raja, S.; Manke, T.; Luscombe, N. M.; Steinmetz, L. M.; Akhtar, A.: Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation. Nature Structural and Molecular Biology 23, pp. 580 - 589 (2016)
  6. 2015
    Journal Article
    Ramirez, F.; Lingg, T.; Toscano, S.; Lam, K.-C.; Georgiev, P.; Chung, H.-R.; Lajoie, B. R.; de Wit, E.; Zhan, Y.; de laat, W. et al.; Dekker, J.; Manke, T.; Akhtar, A.: High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila. Molecular Cell 60, pp. 146 - 162 (2015)
  7. 2014
    Journal Article
    Dias, J.; Van Nguyen, N.; Georgiev, P.; Gaub, A.; Brettschneider, J.; Cusack, S.; Kadlec, J.; Akhtar, A.: Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex. Genes & Development 28, pp. 929 - 942 (2014)
  8. Journal Article
    Dias, J.; Van Nguyen, N.; Georgiev, P.; Gaub, A.; Brettschneider, J.; Cusack, S.; Kadlec, J.; Akhtar, A.: Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is requried for efficient assembly and chromatin targeting of the NSL complex. Genes & Development 28, 942, pp. 929 (2014)
  9. Journal Article
    Quinn, J. J.; Ilik, I. A.; Qu, K.; Georgiev, P.; Chu, C.; Akhtar, A.; Chang, H. Y.: Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification. Nature biotechnology 32, pp. 933 - 940 (2014)
  10. 2013
    Journal Article
    Ilik, I. A.; Quinn, J.; Georgiev, P.; Tavares-Cadete, F.; Maticzka, D.; Toscano, S.; Wan, Y.; Spitale, R. C.; Luscombe, N.; Backofen, R. et al.; Chang, H. Y.; Akhtar, A.: Tandem Stem-Loops in roX RNAs Act Together to Mediate X Chromsome Dosage Compensation in Drosophila. Molecular Cell 51, pp. 156 - 173 (2013)
  11. 2012
    Journal Article
    Hallacli, E.; Lipp, M.; Georgiev, P.; Spielman, C.; Cusack, S.; Akhtar, A.; Kadlec, J.: Msl1-Mediated Dimerization of the Dosage Compensation Complex is Essential for Male X-Chromosome Regulation in Drosophila. Molecular Cell 48, pp. 587 - 600 (2012)
  12. 2011
    Journal Article
    Georgiev, P.; Chlamydas, S.; Akhtar, A.: Drosophila dosage compensation. Fly 5, pp. 147 - 154 (2011)
 
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