Tim Lämmermann: Who defines the traffic rules in the immune system?
Immune cells patrol the blood vessels. Only in the event of inflammation or infection of the tissue, they receive the necessary green light to suddenly leave the vessels. Here, the cells cross the field - attracted by signals emitted by the damaged tissue. Scientists at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg are investigating these movements. The researchers found that the immune cells communicate with each other and show a swarm behavior similar to that of insects. - The video is part of the #wonachsuchstdu campaign of the Max Planck Day 2018.
Tim Lämmermann: Who defines the traffic rules in the immune system? (only available in German)
J. Andrew Pospisilik on “Rethinking DNA as a blueprint for development”
What makes identical twins identical? Genetics is not everything – indeed, studies with mice suggest it is more malleable than has previously been thought. J Andrew Pospisilik, of the Max Planck Institute of Immunobiology and Epigenetics, explains at World Economic Forum 2017 in Dalian what this new understanding implies for unlocking human potential.
J. Andrew Pospisilik - Rethinking DNA as a blueprint for development
Erika Pearce on the question “How Does Metabolism Influence the Function of Different T Cell Types?”
The research presented in this video investigates how the metabolism of the T cells influences the development of effector and memory T cells by blending in vitro and in vivo approaches. Use this link to latestthinking.org to get additional information (chapters, subtitles, papers, beyond science videos).
Erika Pearce - How Does Metabolism Influence the Function of Different T Cell Types?
Asifa Akhtar on the question “How Does the Enzyme MOF Work as a Molecular Bridge between Epigenetics and Metabolism?”
Latest findings of research papers explained by the scientist in an easy manner. This is the concept of latestthinking.org. In this video Asifa Akhtar, group leader at the MPI-IE, explains that the enzyme MOF is not only present in the nucleus but also in the mitochondria and how this finding might provide a new perspective on how changes in the environment that influence the metabolism can impinge on the expression of genes. For additional information (chapters, subtitles papers and a beyond science video section please use this link: latestthinking.org
Asifa Akhtar – How Does the Enzyme MOF Work as a Molecular Bridge between Epigenetics and Metabolism?
Asifa Akhtar on "The beauty of the X chromosome
Asifa Akhtar is heading the Department of Chromatin Regualation. The major goal of her lab is to study the epigenetic mechanisms underlying X-chromosome specific gene regulation using Drosophila dosage compensation as a model system. More specifically, the lab is are interested in addressing how the dosage compensation complex, composed of RNA and proteins (the MSL complex), gets targeted to the X chromosome.
Asifa Akhtar about "The beauty of the X chromosome
Andrew J. Pospisilik and Harald Esterbauer on HO-1 makes Obese sick
Andrew J. Pospisilik, group leader at the MPI-IE, and Prof. DDr. Harald Estenbauer (Medical University of Vienna) explaining results of their study on “Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man” and discussing how this enzyme affects the health of Obese.
Video interview on "HO-1 makes Obese sick"
Who am I not?
Video abstract on Pospisilik et al. 2016 – Cell 163 (3), 353-364.
We are actually a lot closer to the bugs than we thought, at least epigenetically. Watch the video abstract on the newly discovered regulatory, epigenetic switch, which causes individuals with identical genetic material, such as monozygotic twins, to either be lean or obese.
Andrew J. Pospisilik on the Epigenetic Switch for obesity
Epigenetics: Packaging Art in the Cell
Chromatin is a complex of macromolecules in cells dedicated to package the long DNA into a smaller volume to fit in the cell and thereby control gene expression and DNA replication. In this video Thomas Jenuwein, Director of the MPI-IE, explains the principles of Epigenetics and how the changes in in the packaging of the DNA in the cells affects the gene output.
Epigenetics – Packaging Art in the Cell
What is epigenetics?
Thomas Jenuwein, Director at the MPI-IE, on Epigenetics and its potential for a better understanding of development.
What is epigenetics? – Interview with Thomas Jenuwein
Thomas Boehm: Ernst-Jung Prize for Medicine 2014
The Jung Stiftung awards Prof. Dr. Thomas Boehm, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany, the Ernst-Jung Prize for Medicine 2014.
Thomas Boehm - Awardee of the Jung-Preis of Medizine 2014
Thomas Boehm: Education of T cells
In the thymus, T cells of the immune system learn to recognize pathogens. But a strange fish has no thymus: The lamprey. In this video Thomas Boehm, director at the MPI-IE, explains how this fish fights against viruses and bacteria.