Publikationen
Labor Boehm
2024
7, 31 (2024)
Antagonistic interactions safeguard mitotic propagation of genetic and epigenetic information in zebrafish. Communications Biology 2023
8, eadl1470 (2023)
The chilling origin of germinal centers. Science Immunology 44, S. 372 - 383 (2023)
Genetic conflicts and the origin of self/nonself-discrimination in the vertebrate immune system. Trends in Immunology 42, 112933 (2023)
Evolution of two distinct variable lymphocyte receptors in lampreys: VLRD and VLRE. Cell Reports 619, S. 193 - 200 (2023)
Origin and evolutionary malleability of T cell receptor α diversity. Nature 14, 3645 (2023)
Tnpo3 controls splicing of the pre-mRNA encoding the canonical TCR α chain of iNKT cells. Nature Communications 53, 2350402 (2023)
MHC I tetramer staining tends to overestimate the number of functionally relevant self-reactive CD8 T cells in the pre-immune repertoire. European Journal of Immunology 24, 20 (2023)
A survey of the adaptive immune genes of the polka-dot batfish Ogcocephalus cubifrons. BMC Immunology
Lymphocyte pathway analysis using naturally lymphocyte-deficient fish. European Journal of Immunology, e2350577 (2023)
2022
36, S. 901 - 915 (2022)
Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling. Genes and Development 5, 1037 (2022)
Human thymoma-associated mutation of the GTF2I transcription factor impairs thymic epithelial progenitor differentiation in mice. Communications Biology 12, 21401 (2022)
Stage-specific and cell type-specific requirements of ikzf1 during haematopoietic differentiation in zebrafish. Scientific Reports 5, 911 (2022)
Clonal dynamics underlying the skewed CD4/CD8 ratio of mouse thymocytes revealed by TCR-independent barcoding. Communications Biology 12, 13554 (2022)
Limits to in vivo fate changes of epithelia in thymus and parathyroid by ectopic expression of transcription factors Gcm2 and Foxn1. Scientific Reports 606, S. 165 - 171 (2022)
Developmental dynamics of two bipotent thymic epithelial progenitor types. Nature 2021
33, S. 25 - 36 (2021)
Male validation factor for three-spined stickleback (Gasterosteus aculeatus) mate choice likely evolutionarily conserved since 50 thousand years. Ethology, Ecology & Evolution 7, eabd8180 (2021)
Antigen receptor repertoires of one of the smallest known vertebrates. Science Advances 11, 200383 (2021)
Evolution of thymopoietic microenvironments. Open Biology 4, 1201 (2021)
Genetic landscape of T cells identifies synthetic lethality for T-ALL. Communications Biology 2020
11, S. 4505 (2020)
Transgenerational inheritance of impaired larval T cell development in zebrafish. Nature Communications 23, 101260 (2020)
Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1. iScience 59, 102961 (2020)
Long-term robustness of a T-cell system emerging from somatic rescue of a genetic block in T-cell development. EBioMedicine 117, S. 15799 - 15808 (2020)
Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development. Proceedings of the National Academy of Sciences of the United States of America 5, eaba0925 (2020)
Cytidine deaminase 2 is required for VLRB antibody gene assembly in lampreys. Science Immunology 31, 107756 (2020)
Lymphocyte-Specific Function of the DNA Plymerase Epsilon Subunit Pole3 Revealed by Neomorphic Alleles. Cell Reports 369, S. 1608 - 1615 (2020)
The immunogenetics of sexual parasitism. Science 6, eabd9585 (2020)
Retracing the evolutionary emergence of thymopoiesis. Science Advances 65, S. 32 - 41 (2020)
Co-evolution of mutagenic genome deditors and vertebrate adaptive immunity. Current Opinion in Immunology 2019
116, S. 26759 - 26767 (2019)
Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development. Proceedings of the National Academy of Sciences of the United States of America 2018
36, S. 19 - 42 (2018)
Evolution of Alternative Adaptive Immune Systems in Vertebrates. Annual Review of Immunology 14 (12), 20180730, S. 20180730 (2018)
Female assortative mate choice functionally validates synthesized male odours of evolving stickleback river–lake ecotypes. Biology Letters 8, S. 11095 (2018)
Fundamental parameters of the developing thymic epithelium in the mouse. Scientific Reports 115, S. e3211 - e3220 (2018)
Expansions, diversification, and interindividual copy number variations of AID/APOBEC family cytidine deaminase genes in lampreys. Proceedings of the National Academy of Sciences of the United States of America 115, S. E3201 - E3210 (2018)
Diversification of AID/APOBEC-like deaminases in metazoa: multiplicity of clades and widespread roles in immunity. Proceedings of the National Academy of Sciences of the United States of America 215, S. 595 - 610 (2018)
Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors. Journal of Experimental Medicine 48, S. 120 - 127 (2018)
Immunological tolerance to LCMV antigens differently affects control of acute and chronic virus infection in mice. European Journal of Immunology 2017
138, S. 151 - 161 (2017)
Studying the adaptive immune system in zebrafish by transplantation of hematopoietic precursor cells. Methods in Cell Biology 7, 10314 (2017)
Genetic and non-genetic determinants of thymic epithelial cell number and function. Scientific Reports 29, S. 385 - 390 (2017)
Autoimmunity associated with chemically induced thymic dysplasia. International Immunology 7, S. 785 - 902 (2017)
Elevated levels of Wnt signaling disrupt thymus morphogenesis and function. Scientific Reports 7, S. 8492 - 8496 (2017)
Cooperative interaction of BMP signalling and Foxn1 gene dosage determines the size fo the functionally active thymic epithelial compartment. Scientific Reports 2016
271, S. 4 - 9 (2016)
Form follows function, function follows form: how lymphoid tissues enable and constrain immune reactions. Immunological Reviews 6, 19634 (2016)
Stable multilineage xenogeneic replacement of definitive hematopoiesis in adult zebrafish. Scientific Reports 17, S. 2259 - 2270 (2016)
Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development. Cell Reports 2014
2, S. 259 - 283 (2014)
Origin and Evolution of Adaptive Immunity. Annual Review of Animal BioScience 111, S. 14828 - 14833 (2014)
Genomic donor cassette sharing during VLRA and VLRC assembly in jawless vertebrates. Proceedings of the National Academy of Sciences of the United States of America 111, S. 14834 - 14839 (2014)
Selection of the lamprey VLRC antigen receptor repertoire. Proceedings of the National Academy of Sciences of the United States of America 8, S. 1184 - 1197 (2014)
Conversion of the Thymus into a Bipotent Lymphoid Organ by Replacement of Foxn1 with its Paralog Foxn4. Cell Reports 16, S. 125 - 126 (2014)
On the Origin of SCPP genes. Evolution and Development 505, S. 174 - 179 (2014)
Elephant shark genome provides unique insights into gnathostome evolution. Nature 2013
496, S. 304 - 305 (2013)
Sensory Biology. Nature 12, S. 501 - 503 (2013)
Same Function, Different Origins: Multipotent Stromal Precursors in Lymphoid Tissue. Cell Stem Cell 13, S. 831 - 838 (2013)
Thymus involution and regeneration: two sides of the same coin? Nature Reviews Immunology 110, S. 6043 - 6048 (2013)
Organization of lamprey variable lymphocyte receptor C locus and repertoire development. Proceedings of the National Academy of Sciences of the United States of America 110, S. 4327 - 4332 (2013)
Zebrafish model for allogeneic hematopoietic cell transplantation not requiring preconditioning. Proceedings of the National Academy of Sciences of the United States of America 501, S. 435 - 438 (2013)
Evolutionary implications of a third lymphocyte lineage in lampreys. Nature 280, 20122889 (2013)
Major histocompatibility complex peptide ligands as olfactory cues in human body odour assessment. Proceedings of the Royal Society B: Biological Sciences 2012
37, S. 596 - 598 (2012)
Caught in the Act: Reprogramming of Adipocytes into Lymph-Node Stroma. Immunity 22, S. R722 - R732 (2012)
Evolution of Vertebrate Immunity. Current Biology 209, S. 1397 - 1400 (2012)
Self-renewal of thymocytes in the absence of competitive precursor replenishment. Journal of Experimental Medicine 33, S. 315 - 321 (2012)
Evolution of lymphoid tissues. Trends in Immunology 13, S. 127 - 149 (2012)
Evolution of the Immune System in the Lower Vertebrates. Annual Review of Genomics and Human Genetics 30, S. 203 - 220 (2012)
VLR-Based Adaptive Immunity. Annual Review of Immunology 149, S. 159 - 172 (2012)
Synergistic, Context-Dependent, and Hierarchical Functions of Epithelial Components in Thymic Microenvironments. Cell 36, S. 298 - 309 (2012)
Intravital Imaging of Thymopoiesis Reveals Dynamic Lympho-Epithelial Interactions. Immunity 109, S. 3463 - 3468 (2012)
Regenerative capacity of adult cortical thymic epithelial cells. Proceedings of the National Academy of Sciences of the United States of America 2011
470, S. 90 - 94 (2011)
A thymus candidate in lampreys. Nature 11, S. 307 - 317 (2011)
Design principles of adaptive immune systems. Nature Reviews Immunology 108, S. 7517 - 7522 (2011)
Three chemokine receptors cooperatively regulate homing of hematopoietic progenitors to the embryonic mouse thymus. Proceedings of the National Academy of Sciences of the United States of America 186, S. 7060 - 7066 (2011)
Genetic Evidence for an Evolutionarily Conserved Role of IL-7 Signaling in T Cell Development of Zebrafish. Journal of Immunology 2010
107, S. 18079 - 18084 (2010)
Characterization of mononuclear phagocytic cells in medaka fish transgenic for a cxcr3a:gfp reporter. Proceedings of the National Academy of Sciences of the United States of America 107, S. 16613 - 16618 (2010)
Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage. Proceedings of the National Academy of Sciences of the United States of America 277, S. 391 - 398 (2010)
Costly major histocompatibility complex signals produced only by reproductively active males, but not females, must be validated by a "maleness signal" in three-spined sticklebacks. Proceedings of the Royal Society B: Biological Sciences 107, S. 17304 - 17308 (2010)
Essential role of c-myb in definitive hematopoiesis is evolutionarily conserved. Proceedings of the National Academy of Sciences of the United States of America 2009
76, S. 430 (2009)
Genetic Evidence for Monozygotic Twinning in Medaka Fish. Molecular Reproduction and Development 138, S. 186 - 197 (2009)
Evolution of Genetic Networks Underlying the Emergence of Thymopoiesis in Vertebrates. Cell 39, S. 944 - 947 (2009)
The adaptive phenotype of cortical thymic epithelial cells. European Journal of Immunology 10, S. 811 - 813 (2009)
One problem, two solutions. Nature Immunology 12, S. 1551 - 1558 (2009)
Structural requirements for the activation of vomeronasal sensory neurons by MHC peptides. Nature Neuroscience 41, S. 101 - 105 (2009)
Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2. Nature Genetics 31, S. 856 - 858 (2009)
Everything in its Place. Immunity 2008
20, S. 178 - 184 (2008)
Thymus development and function. Current Opinion in Immunology 181, S. 400 - 407 (2008)
Ltβr Signaling Does Not Regulate Aire-Dependent Transcripts in Medullary Thymic Epithelial Cells. Journal of Immunology 181, S. 5272 - 5277 (2008)
Maintenance of Thymic Epithelial Phenotype Requires Extrinsic Signals in Mouse and Zebrafish. Journal of Immunology 2007
8, S. 1031 - 1033 (2007)
Two in one: dual function of an invertebrate antigen receptor. Nature Immunology 8 (2), S. 131 - 135 (2007)
The evolutionary history of lymphoid organs. Nature Immunology 37, S. 2364 - 2366 (2007)
Back to the beginning - the quest for thymic epithelial stem cells. European Journal of Immunology 2006
441, S. 992 - 996 (2006)
Formation of a functional thymus initiated by a postnatal epithelial progenitor cell. Nature 125, S. 845 - 858 (2006)
Quality Control in Self/Nonself Discrimination. Cell 6, S. 79 - 84 (2006)
Co-evolution of a primordial peptide-presentation system and cellular immunity. Nature Reviews Immunology 27, S. 477 - 484 (2006)
Thymus-homing precursors and the thymic microenvironment. Trends in Immunology 29, S. 100 - 107 (2006)
MHC peptides and the sensory evaluation of genotype. Trends in Neurosciences 177, S. 2463 - 2476 (2006)
Conserved Functions of Ikaros in Vertebrate Lymphocyte Development: Genetic Evidence for Distinct Larval and Adult Phases of T Cell Development and Two Lineages of B Cells in Zebrafish. Journal of Immunology 26, S. 1961 - 1970 (2006)
Essential Role of the Main Olfactory System in Social Recognition of Major Histocompatibility Complex Peptide Ligands. The Journal of Neuroscience 312, S. 284 - 287 (2006)
Evidence for a Functional Second Thymus in Mice. Science 2005
175, S. 5213 - 5221 (2005)
BMP Signaling Is Required for Normal Thymus Development. The Journal of Immunology 102, S. 4414 - 4418 (2005)
Mate choice decision of stickleback females predictably modified by MHC peptide ligands. Proceedings of the National Academy of Sciences of the United States of America 2004
24, S. 1649 - 1654 (2004)
Capn5 Is Expressed in a Subset of T Cells and Is Dispensable for Development. Molecular and Cellular Biology (Washington, DC) 306, S. 1033 - 1037 (2004)
MHC Class I Peptide as Chemosensory Signals in the Vomeronasal Organ. Science Weitere Publikationen von Thomas Boehm auf Pubmed.