Gruppenleiter

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Dr. Thomas Boehm
Senior-Gruppenleiter und Direktor
Telefon:+49 761 5108 328
E-Mail:boehm@...

Labor Thomas Boehm

Assistenz: Helen Kirk Tel: +49 761 5108 329 E-Mail: kirk@ie-freiburg.mpg.de

Labor Thomas Boehm

Publikationen (2014-2009)

Origin and evolution of adaptive immunity.
Boehm T, Swann JB. (2014)
Annu Rev Anim Biosci. 2014 Feb;2:259-83. doi: 10.1146/annurev-animal-022513-114201. Epub 2013 Nov 8

Genomic donor cassette sharing during VLRA and VLRC assembly in jawless vertebrates
Das S, Li J, Holland SJ, Iyer LM, Hirano M, Schorpp M, Aravind L, Cooper MD, Boehm T. (2014)
Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14828-33. doi: 10.1073/pnas.1415580111. Epub 2014 Sep 16

Selection of the lamprey VLRC antigen receptor repertoire
Holland S, Gao M, Hirano M, Iyer LM, Luo M, Schorpp M, Cooper MD,  Aravind L, Mariuzza RA, Boehm T. (2014)
Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14834-9. doi: 10.1073/pnas.1415655111. Epub 2014 Sep 16

Conversion of the Thymus into a Bipotent Lymphoid Organ by Replacement of Foxn1 with Its Paralog, Foxn4.
Swann JB, Weyn A, Nagakubo D, Bleul CC, Toyoda A, Happe C, Netuschil N, Hess I, Haas-Assenbaum A, Taniguchi Y, Schorpp M, Boehm T. (2014)
Cell Rep. 2014 Aug 21;8(4):1184-97. doi: 10.1016/j.celrep.2014.07.017. Epub 2014 Aug 14

On the origin of SCPP genes.
Venkatesh B, Lee AP, Ravi V, Maurya AK, Korzh V, Lim ZW, Ingham PW, Boehm T, Brenner S, Warren WC. (2014)
Evol Dev. 2014 May;16(3):125-6. doi: 10.1111/ede.12072. Epub 2014 May 5. No abstract available.

Elephant shark genome provides unique insights into gnathostome evolution.
Venkatesh B, Lee AP, Ravi V, Maurya AK, Lian MM, Swann JB, Ohta Y, Flajnik MF, Sutoh Y, Kasahara M, Hoon S, Gangu V, Roy SW, Irimia M, Korzh V, Kondrychyn I, Lim ZW, Tay BH, Tohari S, Kong KW, Ho S, Lorente-Galdos B, Quilez J, Marques-Bonet T, Raney BJ, Ingham PW, Tay A, Hillier LW, Minx P, Boehm T, Wilson RK, Brenner S, Warren WC. (2014)
Nature. 2014 Jan 9;505(7482):174-9. doi: 10.1038/nature12826.

Thymus involution and regeneration: two sides of the same coin?
Boehm T, Swann JB. (2013)
Nat Rev Immunol. 2013 Nov;13(11):831-8. doi: 10.1038/nri3534.

Evolutionary implications of a third lymphocyte lineage in lampreys.
Hirano M, Guo P, McCurley N, Schorpp M, Das S, Boehm T, Cooper MD. (2013)
Nature. 2013 Sep 19;501(7467):435-8. doi: 10.1038/nature12467.

Same function, different origins: multipotent stromal precursors in lymphoid tissues.
Boehm T. (2013)
Cell Stem Cell. 2013 May 2;12(5):501-3. doi: 10.1016/j.stem.2013.04.011.

Sensory biology: A whiff of genome.
Boehm T. (2013)
Nature. 2013 Apr 18;496(7445):304-5. doi: 10.1038/496304a.

Organization of lamprey variable lymphocyte receptor C locus and repertoire development.
Das S, Hirano M, Aghaallaei N, Bajoghli B, Boehm T, Cooper MD. (2013)
Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6043-8. doi: 10.1073/pnas.1302500110.

Zebrafish model for allogeneic hematopoietic cell transplantation not requiring preconditioning.
Hess I, Iwanami N, Schorpp M, Boehm T. (2013)
Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4327-32. doi: 10.1073/pnas.1219847110.

Major histocompatibility complex peptide ligands as olfactory cues in human body odour assessment.
Milinski M, Croy I, Hummel T, Boehm T. (2013)
Proc Biol Sci. 2013 Jan 23;280(1755):20122889. doi: 10.1098/rspb.2012.2889.

Caught in the act: reprogramming of adipocytes into lymph-node stroma.
Boehm T. (2012)
Immunity. 2012 Oct 19;37(4):596-8. doi: 10.1016/j.immuni.2012.10.001.

Evolution of vertebrate immunity.
Boehm T. (2012)
Curr Biol. 2012 Sep 11;22(17):R722-32. doi: 10.1016/j.cub.2012.07.003.

Self-renewal of thymocytes in the absence of competitive precursor replenishment.
Boehm T. (2012)
J Exp Med. 2012 Jul 30;209(8):1397-400. doi: 10.1084/jem.20121412.

Evolution of the immune system in the lower vertebrates.
Boehm T, Iwanami N, Hess I. (2012)
Annu Rev Genomics Hum Genet. 2012;13:127-49. doi: 10.1146/annurev-genom-090711-163747.

Evolution of lymphoid tissues.
Boehm T, Hess I, Swann JB. (2012)
Trends Immunol. 2012 Jun;33(6):315-21. doi: 10.1016/j.it.2012.02.005.

Synergistic, context-dependent, and hierarchical functions of epithelial components in thymic microenvironments.
Calderón L, Boehm T. (2012)
Cell. 2012 Mar 30;149(1):159-72. doi: 10.1016/j.cell.2012.01.049.

Intravital imaging of thymopoiesis reveals dynamic lympho-epithelial interactions.
Hess I, Boehm T. (2012)
Immunity. 2012 Feb 24;36(2):298-309. doi: 10.1016/j.immuni.2011.12.016.

Regenerative capacity of adult cortical thymic epithelial cells.
Rode I, Boehm T. (2012)
Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3463-8. doi: 10.1073/pnas.1118823109.

VLR-based adaptive immunity.
Boehm T, McCurley N, Sutoh Y, Schorpp M, Kasahara M, Cooper MD. (2012)

Annu Rev Immunol. 2012;30:203-20. doi: 10.1146/annurev-immunol-020711-075038.

Genetic evidence for an evolutionarily conserved role of IL-7 signaling in T cell development of zebrafish.
Iwanami N, Mateos F, Hess I, Riffel N, Soza-Ried C, Schorpp M, Boehm T. (2011)
J Immunol. 2011 Jun 15;186(12):7060-6. doi: 10.4049/jimmunol.1003907. 

Three chemokine receptors cooperatively regulate homing of hematopoietic progenitors to the embryonic mouse thymus.
Calderón L, Boehm T. (2011)
Proc Natl Acad Sci U S A. 2011 May 3;108(18):7517-22. doi: 10.1073/pnas.1016428108.

Design principles of adaptive immune systems.
Boehm T. (2011)
Nat Rev Immunol. 2011 May;11(5):307-17. doi: 10.1038/nri2944.

A thymus candidate in lampreys.
Bajoghli B, Guo P, Aghaallaei N, Hirano M, Strohmeier C, McCurley N, Bockman DE, Schorpp M, Cooper MD, Boehm T. (2011)
Nature. 2011 Feb 3;470(7332):90-4. doi: 10.1038/nature09655.

Characterization of mononuclear phagocytic cells in medaka fish transgenic for a cxcr3a:gfp reporter.
Aghaallaei N, Bajoghli B, Schwarz H, Schorpp M, Boehm T. (2010)
Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18079-84. doi: 10.1073/pnas.1000467107.

Essential role of c-myb in definitive hematopoiesis is evolutionarily conserved.
Soza-Ried C, Hess I, Netuschil N, Schorpp M, Boehm T. (2010)
Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17304-8. doi: 10.1073/pnas.1004640107.

Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage.
Corbeaux T, Hess I, Swann JB, Kanzler B, Haas-Assenbaum A, Boehm T. (2010)
Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16613-8. doi: 10.1073/pnas.1004623107.

Developing T lymphocytes are uniquely sensitive to a lack of topoisomerase III alpha.
Mönnich M, Hess I, Wiest W, Bachrati C, Hickson ID, Schorpp M, Boehm T. (2010)
Eur J Immunol. 2010 Sep;40(9):2379-84. doi: 10.1002/eji.201040634.

Everything in its place.
Swann JB, Boehm T. (2009)
Immunity. 2009 Dec 18;31(6):856-8. doi: 10.1016/j.immuni.2009.11.005.

Costly major histocompatibility complex signals produced only by reproductively active males, but not females, must be validated by a 'maleness signal' in three-spined sticklebacks.
Milinski M, Griffiths SW, Reusch TB, Boehm T. (2010)
Proc Biol Sci. 2010 Feb 7;277(1680):391-8. doi: 10.1098/rspb.2009.1501.

One problem, two solutions.
Boehm T. (2009)
Nat Immunol. 2009 Aug;10(8):811-3. doi: 10.1038/ni0809-811.

Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates.
Bajoghli B, Aghaallaei N, Hess I, Rode I, Netuschil N, Tay BH, Venkatesh B, Yu JK, Kaltenbach SL, Holland ND, Diekhoff D, Happe C, Schorpp M, Boehm T. (2009)
Cell. 2009 Jul 10;138(1):186-97. doi: 10.1016/j.cell.2009.04.017.

The adaptive phenotype of cortical thymic epithelial cells.
Boehm T. (2009)
Eur J Immunol. 2009 Apr;39(4):944-7. doi: 10.1002/eji.200939315.

Genetic evidence for monozygotic twinning in medaka fish.
Aghaallaei N, Takagi A, Boehm T, Bajoghli B. (2009)
Mol Reprod Dev. 2009 May;76(5):430. doi: 10.1002/mrd.21006.

Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2.Pannicke U, Hönig M, Hess I, Friesen C, Holzmann K, Rump EM, Barth TF, Rojewski MT, Schulz A, Boehm T, Friedrich W, Schwarz K. (2009)
Nat Genet. 2009 Jan;41(1):101-5. doi: 10.1038/ng.265.

Does intra-individual major histocompatibility complex diversity keep a golden mean?
Boelfing B, Traulsen A, Milinski M, Boehm T. (2009)
Philos Trans R Soc Lond B Biol Sci. 2009 Jan 12;364(1513):117-28. doi: 10.1098/rstb.2008.0174.

Weitere Publikationen von Thomas Boehm auf Pubmed.

 
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