Forschung

Publikationen

Zeitschriftenartikel (1262)

2020

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Kelly, B.; Pearce, E. L.: Amino Assets: How Amino Acids Support Immunity. Cell Metabolism 32 (2020)
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Klein-Geltink, R.; Edwards-Hicks, J.; Apostolova, P.; O'Sullivan, D.; Sanin, P. D. E.; Annette, E. P.; Puleston, D.; Ligthart, N. A. M.; Büscher, J. M.; Grzes, K. et al.; Kabat, A.; Stanczak, M.; Curtis, J.; Hässler, F.; Uhl, F. M.; Fabri, M.; Zeiser, R.; Pearce, E. J.; Pearce, E. L.: Metabolic conditioning of CD8⁺ effector T cells for adoptive cell therapy. Nature Metabolism (2020)
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Trancoso, I.; Ryo, M.; Boehm, T.: Co-evolution of mutagenic genome deditors and vertebrate adaptive immunity. Current Opinion in Immunology 65, S. 32 - 41 (2020)
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Swann, J.; Holland, S. J.; Petersen, M.; Pietsch, T. W.; Boehm, T.: The immunogenetics of sexual parasitism. Science, S. eaaz9445 (2020)
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Samata, M.; Alexia, A.; Richard, G.; Georgiev, P.; Nuebler, J.; Kulkarni, T.; Renschler, G. V.; Basilicata, M. F.; Zenk, F. L.; Shvedunova, M. et al.; Semplicio, G.; Mirny, L.; Iovino, N.; Akhtar, A.: Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is Instructive for Future Gene Activation. Cell 182, S. 1 - 18 (2020)
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Haring, E.; Uhl, F. M.; Andrieux, G.; Proietti, M.; Bulashevska, A.; Sauer, B.; Braun, L. M.; de Gomez, E. V.; Esser, P. R.; Martin, S. F. et al.; Pfeifer, D.; Follo, M.; Schmitt-Graeff, A.; Büscher, J. M.; Duyster, J.; Grimbacher, B.; Boerries, M.; Pearce, E. L.; Zeiser, R.; Apostolova, P.: Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect. Haematologica (2020)
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Böckelmann, L. C.; Basu, T.; Gründer, A.; Wang, W.; Breucker, J.; Kaiser, S.; Pichler, A.; Pahl, H. L.: Concomitant constitutive LNK and NFE2 mutation with loss of sum9oylation in a case of hereditary thrombocythemia. Haematologica (2020)
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Siamishi, I.; Iwanami, N.; Clapes, T.; Trompouki, E.; O'Meara, C. P.; Boehm, T.: Lymphocyte-Specific Function of the DNA Plymerase Epsilon Subunit Pole3 Revealed by Neomorphic Alleles. Cell Reports 31, S. 107756 (2020)
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Sheikh, B. N.; Guhathakurta, S.; Tsang, T. H.; Schwabenland, M.; Renschler, G. V.; Herquel, B.; Bhardwaj, V.; Holz, H.; Stehle, T.; Bondareva, O. et al.; Aizarni, N.; Mossad, O.; Kretz, O.; Reichardt, W.; Chatterjee, A.; Braun, L. J.; Thevenon, J.; Sartelet, H.; Blank, T.; Grün, D.; von Elverfeldt, D.; Huber, T. B.; Vestweber, D.; Avilov, S.; Prinz, M.; Büscher, J. M.; Akhtar, A.: Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nature Cell Biology (2020)
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Jevtic, V.; Kindle, P.; Avilov, S.: Specific Labeling of Mitochondrial Nucleoids for Time-lapse Structures Illumination Microscopy. Journal of Visualized Experiments 160, S. e60003 (2020)
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van Teijlingen Bakker, N.; Pearce, E. J.: Cell-intrinsic metabolic regulation of mononuclear activation: Findings from the tip of the iceberg. Immunological Reviews 295, S. 54 - 67 (2020)
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Mereu, E.; Lafzi, A.; Moutinho, C.; Ziegenhain, C.; McCarthy, D. J.; Álvarez-Varela, A.; Batlle, E.; Sagar, S.; Grün, D.; Lau, J. K. et al.; Boutet, S. C.; Sanada, C.; Ooi, A.; Jones, R. C.; Kaihara, K.; Brampton, C.; Talaga, Y.; Sasagawa, Y.; Tanaka, K.; Hayashi, T.; Braeuning, C.; Fischer, C.; Sauer, S.; Trefzer, T.; Conrad, C.; Adiconis, X.; Nguyen, L. T.; Regev, A.; Levin, J. Z.; Parekh, S.; Janjic, A.; Wange, L. E.; Bagnoli, J. W.; Enard, W.; Gut, M.; Sandberg, R.; Nikaido, I.; Gut, I.; Stegle, O.; Heyn, H.: Benchmarking single-cell RNA-sequencing protocols for cell atlas projects. Nature Biotechnology (2020)
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Sommerkamp, P.; Altamura, S.; Renders, S.; Narr, A.; Ladel, L.; Zeisberger, P.; Eiben, P. L.; Fawaz, M.; Rieger, M. A.; Cabezas-Wallscheid, N. et al.; Trumpp, A.: Differential Alternative Polyadenylation Landscapes Mediate Hematopoietic Stem Cell Activation and Regulate Glutamine Metabolism. Cell Stem Cell (2020)
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Puleston, D.; Pearce, E. L.: Appetite for Arginine: Metabolic Control of Macrophage Hunger. Cell Metabolism 31, S. 441 - 442 (2020)
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Sagar , S.; Grün, D.: Deciphering Cell Fate Decision by Integrated Single-Cell Sequencing Analysis. Annual Review of Biomedical Data Science 3, S. 1 - 22 (2020)
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Dereka, M.; Herman, J. S.; Cauchy, P.; Ramamoorthy, S.; Lupar, E.; Grün, D.; Grosschedl, R.: EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential. Nature 21, S. 261 - 273 (2020)
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Walther , M.; Schrahn, S.; Krauss, V.; Lein, S.; Kessler, J.; Jenuwein, T.; Reuter, G.: Heterochromatin formation in Drosophila requires genome-weide histone deacetylation in cleavage chromatin before mid-blastula transition in early embryongenesis. Chromosoma: Biology of the Nucleus 129, S. 83 - 98 (2020)
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Ilik, I. A.; Aktas, T.; Maticzka, D.; Backofen, R.; Akhtar, A.: FLASH: ultra-fast protocol to identify RNA-protein interactions in cells. Nucelic Acids Research 48, S. e15 (2020)
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Zenke, S.; Palm, M. M.; Braun, J.; Gavrilov, A.; Meiser, P.; Böttcher, J. P.; Beyersdorf, N.; Ehl, S.; Gerard, A.; Lämmermann, T. et al.; Schumacher, T. N.; Beltman, J. B.; Rohr, J. C.: Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics. Immunity 52, S. 313 - 327 (2020)
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Angiari, S.; Runtsch, M. C.; Sutton, C. E.; Palsson-McDermott, E. M.; Kelly, B.; Rana, N.; Kane, H.; Papadopoulou, G.; Pearce, E. L.; Mills, K. H.G. et al.; O'Neill, L. A.J.: Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4⁺-T Cell Pathogenicity and Suppresses Autoimmunity. Cell Metabolism 31, S. 391 - 405 (2020)