Publications of Dominic Grün

Boisset, J.-C.; Vivie, J.; Grün, D.; Muraro, M. J.; Lyubimova, A.; van Oudenaarden, A.: Mapping the physical network of cellular interactions. Nature methods 15, pp. 547 - 553 (2018)

Costa , F.; Grün, D.; Backofen, R.: GraphDDP: a graph-embedding approach to detect differentiation pathways in single-cell-data using prior class knowledge. Nature Communications 9, p. 3685 (2018)

Lu, T. T.-H.; Heyne, S.; Dror, E.; Casas, E.; Leonhardt, L.; Boenke, T.; Yang, C.-H.; Sagar, S.; Arrigoni, L.; Dalgaard, K. et al.; Teperino, R.; Enders, L.; Selvaraj, M.; Ruf, M.; Raja, S. J.; Xie, H.; Boenisch, U.; Orkin, S. H.; Lynn, F. C.; Hoffman, B. G.; Grün, D.; Vavouri, T.; Lempradl, A. M.; Pospisilik, J. A.: The Polycomb-Dependent Epigenome Controls β Cell Cysfunction, Dedifferentiation, and Diabetes. Cell Metabolism 15, pp. 1294 - 1308 (2018)

Sagar, S.; Hermann, J. S.; Pospisilik, J. A.; Grün, D.: High-Throughput Single-Cell RNA Sequencing and Data Analaysis. Methods in Molecular Biology 1766, pp. 257 - 283 (2018)

Tay, T. L.; Sagar, S.; Dautzenberg, J.; Grün, D.; Prinz, M.: Unique microglia recovery population revealed by single-cell RNAseq following neurodegeneration. Acta Neuropathologica Communications 6, p. 87 (2018)

Tay, T. L.; Mai, D.; Dautzenberg, J.; Fernández-Klett, F.; Lin, G.; Sagar, S.; Datta, M.; Drougard, A.; Stempfl, T.; Ardura-Fabregat, A. et al.; Staszewski, O.; Margineanu, A.; Sporbert, A.; Steinmetz, L. M.; Pospisilik, J. A.; Jung, S.; Priller, J.; Grün, D.; Ronneberger, O.; Prinz, M.: A new fate mapping system reveals context-dependent random or clonal expansion of microglia. Nature Neuroscience 20, pp. 793 - 803 (2017)

Herrtwich, L.; Nanda, I.; Evangelou, K.; Nikolova, T.; Horn, V.; Sagar, S.; Erny, D.; Stefanowski, J.; Rogell, L.; Klein, C. et al.; Gharun, K.; Follo, M.; Seidl, M.; Kremer, B.; Münke, N.; Senges, J.; Fliegauf, M.; Aschman, T.; Pfeifer, D.; Sarrazin, S.; Sieweke, M. H.; Wagner, D.; Dierks, C.; Haaf, T.; Ness, T.; Zaiss, M. M.; Voll, R. E.; Deshmukh, S. D.; Prinz, M.; Goldmann, T.; Hölscher, C.; Hauser, A. E.; Lopez-Contreras, A. J.; Grün, D.; Gorgoulis, V.; Diefenbach, A.; Henneke, P.; Triantafyllopoulou, A.: DNA Damage Signaling Instructs Polypoid Macrophage Fate in Granulomas. Cell 167, pp. 1264 - 1280 (2016)

Muraro, M. J.; Dharmadhikari, G.; Grün, D.; Groen, N.; Dielen, T.; Jansen, E.; van Gurp, L.; Engelse, M. A.; Carlotti, F.; de Koning, E. J.P. et al.; van Oudenaarden, A.: A Single-Cell Transcriptome Atlas of the Human Pancreas. Cell Systems 3, pp. 385 - 394 (2016)

Grün, D.; Muraro, M. J.; Boisset, J.-C.; Wiebrands, K.; Lyubimova, A.; Dharmadhikari, G.; van den Born, M.; Jansen, E.; Clevers, H.; de Koning, E. J.P. et al.; van Oudenaarden, A.: De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data. Cell Stem Cell 19, pp. 266 - 277 (2016)

Wu, C.-C.; Kruse, F.; Vasudevarao, M. D.; Junker, J. P.; Zebrowski, D. C.; Fischer, K.; Noël, E. S.; Grün, D.; Berezikov, E.; Engel, F. B. et al.; van Oudenaarden, A.; Weidinger, G.; Bakkers, J.: Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration. Developmental Cell 36, pp. 36 - 49 (2016)

Grün, D.; Lyubimova, A.; Kester, L.; Wiebrands, K.; Basak, O.; Sasaki, N.; Clevers, H.; van Oudenaarden, A.: Single-cell mRNA sequencing reveales rare intestinal cell types. Nature 525, pp. 251 - 255 (2015)

Grün, D.; Kester, L.; van Oudenaarden, &. A.: Validation of noise models for single-cell transcriptomics enables genome-wiede quentification of stochastic gene expression. Nature methods 11, pp. 637 - 640 (2014)

Grün, D.; Kirchner, M.; Thierfelder, N.; Stoeckius, M.; Selbach, M.; Rajewsky, N.: Conservation of mRNA and protein expression during development of C.elegans. Cell Reports 6, pp. 565 - 577 (2014)

Stoeckius, M.; Grün, D.; Kirchner, M.; Ayoub, S.; Torti, F.; Piano, F.; Herzog, M.; Selbach, M.; Rajewsky, N.: Global characterization of the oocyte‐to‐embryo transition in Caenorhabditis elegans uncovers a novel mRNA clearance mechanism. EMBO Journal 33, pp. 1751 - 1766 (2014)

Stoeckius, M.; Grün, D.; Rajewsky, N.: Paternal RNA contributions of C.elegans zygote. EMBO Journal 33, pp. 1740 - 1750 (2014)

Kim, D. h.; Grün, D.; van Oudenaarden, A.: Dampening of expression oscillation by synchronous regulation of a microRNA and its target. Nature Genetics 45, pp. 1337 - 1344 (2013)

Önal, P.; Grün, D.; Adamidi, C.; Rybak, A.; Solana, J.; Mastrobuoni, G.; Wang, Y.; Rahn, H.; Chen, W.; Kempa, S. et al.; Ziebold, U.; Rajewsky, N.: Molecular determinants of pluripotency are deeply conserved between mammalian and planarian stem cells. EMBO Journal 31, pp. 2755 - 2769 (2012)

Adamidi, C.; Wang, Y.; Grün, D.; Mastrobuoni, G.; You, X.; Tolle, D.; Dodt, M.; Mackowiak, S. D.; Gogol-Doering, A.; Oenal, P. et al.; Rybak, A.; Ross, E.; Alvarado, A. S.; Kempa, S.; Dieterich, C.; Rajewsky, N.; Chen, W.: De novo assembly and vailidation of planaria transcriptome by massive parallel sequencing and shotgun proteomics. Genome Research 21, pp. 1193 - 1120 (2011)

Jungkamp, A.-C.; Stoeckius, M.; Mecenas, D.; Grün, D.; Mastrobuoni, G.; Kempa, S.; Rajewsky, N.: In vivo and treanscritopme-wide identification of RNA-binding protein target sites. Molecular Cell 44, pp. 828 - 840 (2011)

Lall, S.; Grün, D.; Krek, A.; Chen, K.; Wang, Y.-L.; Dewey, C. N.; Sood, P.; Colombo, T.; Bray, N.; MacMenamin, P. et al.; Kao, H.-L.; Gunsalus, K. C.; Pachter, L.; Piano, F.; Rajewsky, N.: A genome-wide map of conserved microRNA targets in C.elegans. Current Biology 16, pp. 460 - 471 (2006)

Grün, D.; Wang, Y.-L.; Langenberger, D.; Gunsalus, K. C.; Rajewsky, N.: microRNA target prediction across seven Drosophila species and comparison to mammalian targets. PLoS Computational Biology 1, p. e13 (2005)

Krek, A.; Grün, D.; Poy, M. N.; Wolf, R.; Rosenberg, L.; Epstein, E. J.; MacMenamin, P.; da Piedade, I.; Gunsalus, K. C.; &, M. S. et al.; Rajewsky, N.: Combinatorial microRNA target predictions. Nature Genetics 37, pp. 495 - 500 (2005)

Sagar, S.; Grün, D.: Lineage Inference and Stem Cell Identity prediction Using Single-Cell RNA-Sequencing Data. In: Methods in Molecular Biology, pp. 227 - 301. Humana Press, Clifton, N.J. (2019)

Grün, D.; Rajewsky, N.: Computional prediction of microRNA targets in vertebrates, fruitflies and nematodes. In: MicroRNAs: From Basic Science to Disease Biology, pp. 172 - 186. Cambridge University Press (2008)