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Journal Article (41)

  1. 2020
    Journal Article
    Sheikh, B. N.; Guhathakurta, S.; Tsang, T. H.; Schwabenland, M.; Renschler, G. V.; Herquel, B.; Bhardwaj, V.; Holz, H.; Stehle, T.; Bondareva, O. et al.; Aizarni, N.; Mossad, O.; Kretz, O.; Reichardt, W.; Chatterjee, A.; Braun, L. J.; Thevenon, J.; Sartelet, H.; Blank, T.; Grün, D.; von Elverfeldt, D.; Huber, T. B.; Vestweber, D.; Avilov, S.; Prinz, M.; Büscher, J. M.; Akhtar, A.: Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nature Cell Biology (2020)
  2. Journal Article
    Mereu, E.; Lafzi, A.; Moutinho, C.; Ziegenhain, C.; McCarthy, D. J.; Álvarez-Varela, A.; Batlle, E.; Sagar, S.; Grün, D.; Lau, J. K. et al.; Boutet, S. C.; Sanada, C.; Ooi, A.; Jones, R. C.; Kaihara, K.; Brampton, C.; Talaga, Y.; Sasagawa, Y.; Tanaka, K.; Hayashi, T.; Braeuning, C.; Fischer, C.; Sauer, S.; Trefzer, T.; Conrad, C.; Adiconis, X.; Nguyen, L. T.; Regev, A.; Levin, J. Z.; Parekh, S.; Janjic, A.; Wange, L. E.; Bagnoli, J. W.; Enard, W.; Gut, M.; Sandberg, R.; Nikaido, I.; Gut, I.; Stegle, O.; Heyn, H.: Benchmarking single-cell RNA-sequencing protocols for cell atlas projects. Nature Biotechnology (2020)
  3. Journal Article
    Sagar , S.; Grün, D.: Deciphering Cell Fate Decision by Integrated Single-Cell Sequencing Analysis. Annual Review of Biomedical Data Science 3, pp. 1 - 22 (2020)
  4. Journal Article
    Dereka, M.; Herman, J. S.; Cauchy, P.; Ramamoorthy, S.; Lupar, E.; Grün, D.; Grosschedl, R.: EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential. Nature 21, pp. 261 - 273 (2020)
  5. Journal Article
    Grün, D.: Revealing dynamics of gene expression variability in cell state space. Nature methods, pp. 45 - 49 (2020)
  6. Journal Article
    Rodrigues, C. P.; Herman, J. S.; Herquel, B.; Velsecchi Keller, C. I.; Stehle, T.; Grün, D.; Akhtar, A.: Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate. Science Advances 6, p. eaaz4815 (2020)
  7. Journal Article
    Sagar, S.; Pokrovskii, M.; Herman, J. S.; Naik, S.; Sock, E.; Zeis, P.; Lausch, U.; Wegner, M.; Tanriver, Y.; Littman, D. R. et al.; Grün, D.: Deciphering the regulatory landscapte of fetal and adult γδ T-cell development at single-cell resolution. The EMBO Journal 39, p. e104159 (2020)
  8. 2019
    Journal Article
    Sankowski, R.; Böttcher, C.; Masuda, T.; Geirsdottir, L.; Sagar, S.; Sindram, E.; Seredenina, T.; Muhs, A.; Scheiwe, C.; Shah, M. J. et al.; Heiland, D. H.; Schnell, O.; Grün, D.; Priller, J.; Prinz, M.: Mapping microglia states in teh human brain through the integration of high-dimensional techniques. Nature Neuroscience 22, pp. 2098 - 2110 (2019)
  9. Journal Article
    Sheikh, B. N.; Bondareva, O.; Guhathakurta, S.; Tsang, T. H.; Sikora, K.; Aizarani, N.; Sagar, S.; Holz, H.; Grün, D.; Hein, L. et al.; Akhtar, A.: Systematic Identification of Cell-Cell Communication Networks in the Developing Brain. iScience 21, pp. 273 - 287 (2019)
  10. Journal Article
    Grün, D.: Revealing dynamics of gene expression variability in cell state space. Nature methods (2019)
  11. Journal Article
    Aizarani, N.; Saviano, A.; Sagar, S.; Mailly , L.; Durand, S.; Herman, J. S.; Pessaux, P.; Baumert , T. F.; Grün, D.: A human liver cell atlas reveals heterogeneity and epithelial progenitors. Nature 572, pp. 199 - 204 (2019)
  12. Journal Article
    Masuda, T.; Sankowski, R.; Staszewski, O.; Böttcher, C.; Amann, L.; Sagar, S.; Scheiwe, C.; Nessler, S.; Kunz, P.; van Loo, G. et al.; Coenen, V. A.; Reinacher, P. C.; Michel, A.; Sure, U.; Gold, R.; Grün, D.; Priller, J.; Stadelmann, C.; Prinz, M.: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature 566, pp. 388 - 392 (2019)
  13. Journal Article
    Jordão, M. J. C.; Sankowski, R.; Brendecke, S. M.; Sagar, S.; Locatelli, G.; Tai, Y.-H.; Tay, T. L.; Schramm, E.; Armbruster, S.; Hagemeyer, N. et al.; Groß, O.; Mai, D.; Çiçek, Ö.; Falk, T.; Kerschensteiner, M.; Grün, D.; Prinz, M.: Single-cell profiling identifies myeloid cell subsets with distinct fates during neuro inflammation. Science 363 (2019)
  14. Journal Article
    Kolter, J.; Feuerstein, R.; Zeis, P.; Hagemeyer, N.; Paterson, N.; d’Errico, P.; Baasch, S.; Amann, L.; Masuda, T.; Lösslein, A. et al.; Gharun, K.; Meyer-Luehmann, M.; Waskow, C.; Franzke, C.-W.; Grün, D.; Lämmermann, T.; Prinz, M.; Henneke, P.: A Subset of Skin Macrophages Contributes to the Seruveillance and Regeneration of Local Nerves. Immunity 50, pp. 1482 - 1497 (2019)
  15. Journal Article
    Sankowski, R.; Böttcher, C.; Masuda, T.; Geirsdottir, L.; Sagar, S.; Sindram, E.; Seredenina, T.; Muhs, A.; Scheiwe, C.; Shah, M. J. et al.; Heiland, D. H.; Schnell, O.; Grün, D.; Priller, J.; Prinz, M.: Mapping microglia states in the human brain through the integration of high-dimensional techniques. Nature Neuroscience 22, pp. 2098 - 2110 (2019)
  16. 2018
    Journal Article
    Roovers, E. F.; Kaaij, L. J.T.; Redl, S.; Bronkhorst, A. W.; Wiebrands, K.; de Domingues, A. M. J.; Huang, H.-Y.; Han, C.-T.; Riemer, S.; Dosch, R. et al.; Salvenmoser, W.; Grün, D.; Butter, F.; van Oudenaarden, A.; Ketting, R. F.: Tdrd6a Regulates the Aggregation of Buc into Functional Subcellular Compartments that Drive Germ Cell Specification. Developmental Cell 46, pp. 285 - 301 (2018)
  17. Journal Article
    Herman, J. S.; Sagar, S.; Grün, D.: FateID infers fate bias in multipotent progenitors from single-cell RNA-seq data. Nature methods 15, pp. 379 - 386 (2018)
  18. Journal Article
    Felmlee, D. J.; Baumert, T. F.; Grün, D.: Zooming in on Liver Zonation. Hepatology 67, pp. 784 - 787 (2018)
  19. Journal Article
    Boisset, J.-C.; Vivie, J.; Grün, D.; Muraro, M. J.; Lyubimova, A.; van Oudenaarden, A.: Mapping the physical network of cellular interactions. Nature methods 15, pp. 547 - 553 (2018)
  20. Journal Article
    Costa , F.; Grün, D.; Backofen, R.: GraphDDP: a graph-embedding approach to detect differentiation pathways in single-cell-data using prior class knowledge. Nature Communications 9, p. 3685 (2018)
  21. Journal Article
    Grün, D.: Revealing routes of cellular differentiation by single-cell RNA-seq. Current Opinion in Systems Biology 11, pp. 9 - 17 (2018)
  22. Journal Article
    Lu, T. T.-H.; Heyne, S.; Dror, E.; Casas, E.; Leonhardt, L.; Boenke, T.; Yang, C.-H.; Sagar, S.; Arrigoni, L.; Dalgaard, K. et al.; Teperino, R.; Enders, L.; Selvaraj, M.; Ruf, M.; Raja, S. J.; Xie, H.; Boenisch, U.; Orkin, S. H.; Lynn, F. C.; Hoffman, B. G.; Grün, D.; Vavouri, T.; Lempradl, A. M.; Pospisilik, J. A.: The Polycomb-Dependent Epigenome Controls β Cell Cysfunction, Dedifferentiation, and Diabetes. Cell Metabolism 15, pp. 1294 - 1308 (2018)
  23. Journal Article
    Sagar, S.; Hermann, J. S.; Pospisilik, J. A.; Grün, D.: High-Throughput Single-Cell RNA Sequencing and Data Analaysis. Methods in Molecular Biology 1766, pp. 257 - 283 (2018)
  24. Journal Article
    Tay, T. L.; Sagar, S.; Dautzenberg, J.; Grün, D.; Prinz, M.: Unique microglia recovery population revealed by single-cell RNAseq following neurodegeneration. Acta Neuropathologica Communications 6, p. 87 (2018)
  25. 2017
    Journal Article
    Tay, T. L.; Mai, D.; Dautzenberg, J.; Fernández-Klett, F.; Lin, G.; Sagar, S.; Datta, M.; Drougard, A.; Stempfl, T.; Ardura-Fabregat, A. et al.; Staszewski, O.; Margineanu, A.; Sporbert, A.; Steinmetz, L. M.; Pospisilik, J. A.; Jung, S.; Priller, J.; Grün, D.; Ronneberger, O.; Prinz, M.: A new fate mapping system reveals context-dependent random or clonal expansion of microglia. Nature Neuroscience, pp. 793 - 803 (2017)
  26. 2016
    Journal Article
    Herrtwich, L.; Nanda, I.; Evangelou, K.; Nikolova, T.; Horn, V.; Sagar, S.; Erny, D.; Stefanowski, J.; Rogell, L.; Klein, C. et al.; Gharun, K.; Follo, M.; Seidl, M.; Kremer, B.; Münke, N.; Senges, J.; Fliegauf, M.; Aschman, T.; Pfeifer, D.; Sarrazin, S.; Sieweke, M. H.; Wagner, D.; Dierks, C.; Haaf, T.; Ness, T.; Zaiss, M. M.; Voll, R. E.; Deshmukh, S. D.; Prinz, M.; Goldmann, T.; Hölscher, C.; Hauser, A. E.; Lopez-Contreras, A. J.; Grün, D.; Gorgoulis, V.; Diefenbach, A.; Henneke, P.; Triantafyllopoulou, A.: DNA Damage Signaling Instructs Polypoid Macrophage Fate in Granulomas. Cell 167, pp. 1264 - 1280 (2016)
  27. Journal Article
    Muraro, M. J.; Dharmadhikari, G.; Grün, D.; Groen, N.; Dielen, T.; Jansen, E.; van Gurp, L.; Engelse, M. A.; Carlotti, F.; de Koning, E. J.P. et al.; van Oudenaarden, A.: A Single-Cell Transcriptome Atlas of the Human Pancreas. Cell Systems 3, pp. 385 - 394 (2016)
  28. Journal Article
    Grün, D.; Muraro, M. J.; Boisset, J.-C.; Wiebrands, K.; Lyubimova, A.; Dharmadhikari, G.; van den Born, M.; Jansen, E.; Clevers, H.; de Koning, E. J.P. et al.; van Oudenaarden, A.: De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data. Cell Stem Cell 19, pp. 266 - 277 (2016)
  29. Journal Article
    Wu, C.-C.; Kruse, F.; Vasudevarao, M. D.; Junker, J. P.; Zebrowski, D. C.; Fischer, K.; Noël, E. S.; Grün, D.; Berezikov, E.; Engel, F. B. et al.; van Oudenaarden, A.; Weidinger, G.; Bakkers, J.: Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration. Developmental Cell 36, pp. 36 - 49 (2016)
  30. 2015
    Journal Article
    Grün, D.; Lyubimova, A.; Kester, L.; Wiebrands, K.; Basak, O.; Sasaki, N.; Clevers, H.; van Oudenaarden, A.: Single-cell mRNA sequencing reveales rare intestinal cell types. Nature 525, pp. 251 - 255 (2015)
 
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