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Journal Article (24)

  1. 2019
    Journal Article
    Ramisch, A.; Heinrich, V.; Glaser, L. V.; Fuchs, A.; Yang, X.; Benner, P.; Schöpflin, R.; Li, N.; Kinkley, S.; Römer-Hillmann, A. et al.; Longinotto, J.; Heyne, S.; Czepukojc, B.; Kessler, S. M.; Kiemer, A. K.; Cadenas, C.; Arrigoni, L.; Gasparoni, N.; Manke, T.; Pap, T.; Pospisilik, A.; Hengstler, J.; Walter, J.; Meijsing, S. H.; Chung, H.-R.; Vingron, M.: CRUP: a comprehensive framework to predict condition-specific regulatory units. Genome Biology: Biology for the Post-Genomic Era 20, p. 227 (2019)
  2. 2018
    Journal Article
    Timper, K.; Paeger, L.; Sánchez-Lasheras, C.; Varela, L.; Jais, A.; Nolte, H.; Vogt, M. C.; Hausen, C.; Heilinger, C.; Evers, N. et al.; Pospisilik, J. A.; Penninger, J. M.; Taylor, E. B.; Horvath, T. L.; Kloppenburg, P.; Brüning, J. C.: Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity. Cell Reports 25, pp. 383 - 397 (2018)
  3. Journal Article
    Arrigoni, L.; Al-Hasani, H.; Ramírez, F.; Panzeri, I.; Ryan, D. P.; Santacruz, D.; Kress, N.; Pospisilik, J. A.; Bönisch, U.; Manke, T.: RELACS nuclei barcoding enables high-throughput ChIP-seq. Communications Biology 214 (2018)
  4. Journal Article
    Lu, T. T.-H.; Heyne, S.; Dror, E.; Casas, E.; Leonhardt, L.; Boenke, T.; Yang, C.-H.; Sagar, S.; Arrigoni, L.; Dalgaard, K. et al.; Teperino, R.; Enders, L.; Selvaraj, M.; Ruf, M.; Raja, S. J.; Xie, H.; Boenisch, U.; Orkin, S. H.; Lynn, F. C.; Hoffman, B. G.; Grün, D.; Vavouri, T.; Lempradl, A. M.; Pospisilik, J. A.: The Polycomb-Dependent Epigenome Controls β Cell Cysfunction, Dedifferentiation, and Diabetes. Cell Metabolism 15, pp. 1294 - 1308 (2018)
  5. Journal Article
    Panzeri, I.; Pospisilik, J. A.: Epigenetic control of variation and stochasticity in metabolic disease. Molecular Metabolism 14, pp. 26 - 38 (2018)
  6. 2017
    Journal Article
    Costantino, S.; Paneni, F.; Virdis, A.; Hussain, S.; Mohammed, S. A.; Capretti, G.; Akhmedov, A.; Dalgaard, K.; Chiandotto, S.; Pospisilik, J. A. et al.; Jenuwein, T.; Giorgio, M.; Volpe, M.; Taddei, S.; Lüscher, T. F.; Cosentino, F.: Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity. European Heart Journal 40, pp. 383 - 391 (2017)
  7. Journal Article
    Tay, T. L.; Mai, D.; Dautzenberg, J.; Fernández-Klett, F.; Lin, G.; Sagar, S.; Datta, M.; Drougard, A.; Stempfl, T.; Ardura-Fabregat, A. et al.; Staszewski, O.; Margineanu, A.; Sporbert, A.; Steinmetz, L. M.; Pospisilik, J. A.; Jung, S.; Priller, J.; Grün, D.; Ronneberger, O.; Prinz, M.: A new fate mapping system reveals context-dependent random or clonal expansion of microglia. Nature Neuroscience, pp. 793 - 803 (2017)
  8. 2016
    Journal Article
    Dalgaard, K.; Landgraf, K.; Heyne, S.; Lempradl, A.; Longinotto, J.; Gossens, K.; Ruf, M.; Orthofer, M.; Strogantsev, R.; Selvaraj, M. et al.; Lu, T. T.-H.; Casas, E.; Teperino, R.; Surani, M. A.; Zvetkova, I.; Rimmington, D.; Tung, Y.C. L.; Lam, B.; Larder, R.; Yeo, G. S.H.; O’Rahilly, S.; Vavouri, T.; Whitelaw, E.; Penninger, J. M.; Jenuwein, T.; Cheung, C.-L.; Ferguson-Smith, A. C.; Coll, A. P.; Körner, A.; Pospisilik, J. A.: Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity. Cell 164, pp. 353 - 364 (2016)
  9. 2015
    Journal Article
    Lempradl, A.; Pospisilik, J. A.; Penninger, J. M.: Exploring the emerging complexity in transcription regulation of energy homeostasis. Nature Reviews Genetics 16, pp. 665 - 681 (2015)
  10. Journal Article
    Öst, A.; Pospisilik, J. A.: Epigenetic modulation of metabolic decisions. Current Opinion in Cell Biology 33, pp. 88 - 94 (2015)
  11. 2014
    Journal Article
    Oest, A.; Lempradl, A.; Casas, E.; Weigert, M.; Tiko, T.; Deniz, M.; Pantano, L.; Boenisch, U.; Itskov, P. M.; Stoeckius, M. et al.; Ruf, M.; Rajewsky, N.; Reuter, G.; Iovino, N.; Ribiero, C.; Alenius, M.; Heyne, S.; Vavouri, T.; Pospisilik, J. A.: Paternal Diet Defines Offspring Chromatin State and Intergenerational Obesity. Cell 159, pp. 1352 - 1364 (2014)
  12. Journal Article
    Jais, A.; Einwallner, E.; Sharif, O.; Gossens, K.; Tsai-Hsiu Lu, T.; Soyal, S. M.; Medgyesi, D.; Neureiter, D.; Paier-Pourani, J.; Dalgaard, K. et al.; Duvigneau, J. C.; Lindroos-Christensen, J.; Zapf, T.-C.; Amann, S.; Saluzzo, S.; Jantscher, F.; Stiedl, P.; Todoric, J.; Martins, R.; Oberkofler, H.; Müller, S.; Hauser-Kronberger, C.; Kenner, L.; Casanova, E.; Sutterlüty-Fall, H.; Bilban, M.; Miller, K.; Kozlov, A. V.; Krempler, F.; Knapp, S.; Lumeng, C. N.; Patsch, W.; Wagner, O.; Pospisilik, J. A.; Esterbauer, H.: Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man. Cell 158, pp. 25 - 40 (2014)
  13. Journal Article
    Teperino, R.; Aberger, F.; Esterbauer, H.; Riobo, N.; Pospisilik, J. A.: Canonical and non-canonical Hedgehog signalling and the control of metabolism. Seminars in Cell & Developmental Biology 33, pp. 81 - 92 (2014)
  14. 2013
    Journal Article
    Lindroos, J.; Husa, J.; Mitterer, G.; Haschemi, A.; Rauscher, S.; Haas, R.; Gröger, M.; Loewe, R.; Kohrgruber, N.; Schrögendorfer, K. F. et al.; Prager, G.; Beck, H.; Pospisilik, J. A.; Zeyda, M.; Stulnig, T. M.; Patsch, W.; Wagner, O.; Esterbauer, H.; Bilban, M.: Human but Not Mouse Adipogenesis Is Critically Dependent on LMO3. Cell Metabolism 18, pp. 62 - 74 (2013)
  15. Journal Article
    Pospisilik, J. A.: Metabolism shaping chromatin shaping metabolism. Cellular and Molecular Life Sciences 70, pp. 1493 - 1494 (2013)
  16. Journal Article
    Teperino, R.; Lempradl, A.; Pospisilik, J. A.: Bridging epigenomics and complex disease: the basics. Cell and Molecular Life Sciences 70, pp. 1609 - 1621 (2013)
  17. 2012
    Journal Article
    Teperino, R.; Amann, S.; Bayer, M.; McGee, S. L.; Loipetzberger, A.; Connor, T.; Jaeger, C.; Kammerer, B.; Winter, L.; Wiche, G. et al.; Dalgaard, K.; Selvaraj, M.; Gaster, M.; Lee-Young, R. S.; Febbraio, M. A.; Knauf, C.; Cani, P. D.; Aberger, F.; Penninger, J. M.; Pospisilik, J. A.; Esterbauer, H.: Hedgehog Partial Agonism Drives Warburg-like Metabolism in Muscle and Brown Fat. Cell 151, pp. 414 - 426 (2012)
  18. Journal Article
    Haschemi, A.; Kosma, P.; Gille, L.; Evans, C. R.; Burant, C. F.; Starkl, P.; Knapp, B.; Haas, R.; Schmid, J. A.; Jandl, C. et al.; Amir, S.; Lubec, G.; Park, J.; Esterbauer, H.; Bilban, M.; Pospisilik, J. A.; Otterbein, L. E.; Wagner, O.: The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism. Cell Metabolism 15, pp. 813 - 826 (2012)
  19. 2011
    Journal Article
    Schramek, D.; Kotsinas, A.; Meixner, A.; Wada, T.; Elling, U.; Pospisilik, J. A.; Neely, G. G.; Zwick, R.-H.; Sigl, V.; Forni, G. et al.; Serrano, M.; Gorgoulis, V. G.; Penninger, J. M.: The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression. Nature Genetics 43, pp. 212 - 219 (2011)
  20. Journal Article
    Mueller, K.; Kornfeld, J.-W.; Friedbichler, K.; Blaas, L.; Egger, G.; Esterbauer, H.; Hasselblatt, P.; Schlederer, M.; Haindl, S.; Wagner, K.-U. et al.; Engblom, D.; Haemmerle, G.; Kratky, D.; Sexl, V.; Kenner, L.; Kozlov, A. V.; Terracciano, L.; Zechner, R.; Schuetz, G.; Casanova, E.; Pospisilik, J. A.; Heim, M. H.; Moriggi, R.: Impairment of Hepatic Growth Hormone and Glucocorticoid Receptor Signaling Causes Steatosis and Hepatocellular Carcinoma in Mice. Hepatology 54, pp. 1398 - 1409 (2011)
  21. Journal Article
    Todoric, J.; Strobl, B.; Jais, A.; Boucheron, N.; Bayer, M.; Amann, S.; Lindroos, J.; Teperino, R.; Prager, G.; Bilban, M. et al.; Ellmeier, W.; Krempler, F.; Müller, M.; Wagner, O.; Patsch, W.; Pospisilik, J. A.; Esterbauer, H.: Cross-Talk Between Interferon-γ and Hedgehog Signaling Regulates Adipogenesis. Diabetes 60, pp. 1668 - 1676 (2011)
  22. 2010
    Journal Article
    Neely, G. G.; Hess, A.; Costigan, M.; Keene, A. C.; Goulas, S.; Langeslag, M.; Griffin, R. S.; Belfer, I.; Dai, F.; Smith, S. B. et al.; Diatchenko, L.; Gupta, V.; Xia, C.-p.; Amann, S.; Kreitz, S.; Heindl-Erdmann, C.; Wolz, S.; Ly, C. V.; Arora, S.; Sarangi, R.; Dan, D.; Novatchkova, M.; Rosenzweig, M.; Gibson, D. G.; Truong, D.; Schramek, D.; Zoranovic, T.; Cronin, S. J. F.; Angjeli, B.; Brune, K.; Dietzl, G.; Maixner, W.; Meixner, A.; Thomas, W.; Pospisilik, J. A.; Alenius, M.; Kress, M.; Subramaniam, S.; Garrity, P. A.; Bellen, H. J.; Woolf, C. J.; Penninger, J. M.: A genome-wide Drosophila screen for heat nociception identifies α2δ3 as a evolutionarily conserved pain gene. Cell 143, pp. 628 - 638 (2010)
  23. Journal Article
    Neely, G. G.; Kuba, K.; Cammarato, A.; Isobe, K.; Amann, S.; Zhang, L.; Murata, M.; Elmén, L.; Gupta, V.; Arora, S. et al.; Sarangi, R.; Dan, D.; Fujisawa, S.; Usami, T.; Xia, C.-p.; Keene, A. C.; Alayari, N. N.; Yamakawa, H.; Elling, U.; Berger, C.; Novatchkova, M.; Koglgruber, R.; Fukada, K.; Nishina, H.; Isobe, M.; Pospisilik, J. A.; Yumiko, I.; Pfeufer, A.; Hicks, A.; Pramstaller, P. P.; Subramaniam, S.; Kimura, A.; Ocorr, K.; Bodmer, R.; Penninger, J. M.: A Global In vivo Drosophila RNAi Screen Identifies NOT3 as a Conserved Regulator of Heart Function. Cell 141, pp. 142 - 153 (2010)
  24. Journal Article
    Pospisilik, J. A.; Schramek, D.; Schnidar, H.; Cronin, S. J. F.; Nehme, N. T.; Zhang, X.; Knauf, C.; Cani, P. D.; Aumayr, K.; Todoric, J. et al.; Bayer, M.; Haschemi, A.; Puvindran, V.; Tar, K.; Orthofer, M.; Neely, G. G.; Dietzl, G.; Manoukian, A.; Funovics, M.; Prager, G.; Wagner, O.; Ferrandon, D.; Aberger, F.; Hui, C.-c.; Esterbauer, H.; Penninger, J. M.: Drosophila Genome-wide Obesity Screen Reveals Hedgehog as a Determinant of Brown versus White Adipose Cell Fate. Cell 140, pp. 148 - 160 (2010)

Book Chapter (1)

  1. 2015
    Book Chapter
    Teperino, R.; Pospisilik, J. A.: Determination and analysis of Cellular Metabolic Changes by Noncanonical Hedgehog Signaling. In: Methods in Molecular Biology, Vol. 1322, pp. 187 - 198. Springer Science + Business Media, New York (2015)
 
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