Publications of Thomas Boehm

Nusser, A.; Sagar; Swann, J.; Krauth, B.; Diekhoff, D.; Calderon, L.; Happe, C.; Grün, D.; Boehm, T.: Developmental dynamics of two bipotent thymic epithelial progenitor types. Nature (2022)

O’Meara, C. P.; Guerri, L.; Lawir, D.-F.; Mateos, F.; Iconomou, M.; Iwanami, N.; Soza-Ried, C.; Sikora, K.; Siamishi, I.; Giorgetti, O. B. et al.; Peter, S.; Schorpp, M.; Boehm, T.: Genetic landscape of T cells identifies synthetic lethality for T-ALL. Communications Biology 4, 1201 (2021)

Morimoto, R.; Swann, J.; Nusser, A.; Trancoso, I.; Schorpp, M.; Boehm, T.: Evolution of thymopoietic microenvironments. Open Biology 11, 200383 (2021)

Gahr, C. L.; Boehm, T.; Milinski, M.: Male validation factor for three-spined stickleback (Gasterosteus aculeatus) mate choice likely evolutionarily conserved since 50 thousand years. Ethology, Ecology & Evolution 33, pp. 25 - 36 (2021)

Giorgetti, O. B.; Shingate, P.; O’Meara, C. P.; Ravi, V.; Pillai, N. E.; Tay, B.-H.; Prasad, A.; Iwanami, N.; Tan, H. H.; Schorpp, M. et al.; Venkatesh, B.; Boehm, T.: Antigen receptor repertoires of one of the smallest known vertebrates. Science Advances 7, eabd8180 (2021)

Swann, J.; Nusser, A.; Morimoto, R.; Nagakubo, D.; Boehm, T.: Retracing the evolutionary emergence of thymopoiesis. Science Advances 6, eabd9585 (2020)

Swann, J.; Holland, S. J.; Petersen, M.; Pietsch, T. W.; Boehm, T.: The immunogenetics of sexual parasitism. Science 369, pp. 1608 - 1615 (2020)

Iwanami, N.; Lawir, D.-F.; Sikora, K.; Meara, C. O.; Takeshita, K.; Schorpp, M.; Boehm, T.: Transgenerational inheritance of impaired larval T cell development in zebrafish. Nature Communications 11, p. 4505 (2020)

Kury, P.; Führer, M.; Fuchs, S.; Lorenz, M. R.; Giorgetti, O. B.; Bakhtiar, S.; Frei, A. P.; Fisch, P.; Boehm, T.; Schwarz, K. et al.; Speckmann, C.; Ehl, S.: Long-term robustness of a T-cell system emerging from somatic rescue of a genetic block in T-cell development. EBioMedicine 59, 102961 (2020)

Trancoso, I.; Morimoto, R.; Boehm, T.: Co-evolution of mutagenic genome deditors and vertebrate adaptive immunity. Current Opinion in Immunology 65, pp. 32 - 41 (2020)

Iwanami, N.; Takeshita, K.; Lawir, D.-F.; Suetake, I.; Tajima, S.; Sikora, K.; Trancoso, I.; O'Meara, C.; Siamishi, I.; Takahama, Y. et al.; Furutani-Seiki, M.; Kondoh, H.; Yonezawa, Y.; Schorpp, M.; Boehm, T.: Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1. iScience 23, 101260 (2020)

Lawir, D.-F.; Sikora, K.; O'Meara, C. P.; Schorpp, M.; Boehm, T.: Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development. Proceedings of the National Academy of Sciences of the United States of America 117, pp. 15799 - 15808 (2020)

Siamishi, I.; Iwanami, N.; Clapes, T.; Trompouki, E.; O'Meara, C. P.; Boehm, T.: Lymphocyte-Specific Function of the DNA Plymerase Epsilon Subunit Pole3 Revealed by Neomorphic Alleles. Cell Reports 31, 107756 (2020)

Morimoto, R.; O’Meara, C. P.; Holland, S. J.; Trancoso, I.; Souissi, A.; Schorpp, M.; Vassaux, D.; Iwanami, N.; Giorgetti, O. B.; Evanno, G. et al.; Boehm, T.: Cytidine deaminase 2 is required for VLRB antibody gene assembly in lampreys. Science Immunology 5, eaba0925 (2020)

Lawir, D.-F.; Hess, I.; Sikora, K.; Iwanami, N.; Siamishi, I.; Schorpp, M.; Boehm, T.: Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development. Proceedings of the National Academy of Sciences of the United States of America 116, pp. 26759 - 26767 (2019)

Gahr, C. L.; Boehm, T.; Milinski, M.: Female assortative mate choice functionally validates synthesized male odours of evolving stickleback river–lake ecotypes. Biology Letters 14 (12), 20180730, p. 20180730 (2018)

Woopen, C.; Straub, T.; Schweier, O.; Aichele, U.; Düker, K.; Boehm, T.; Pircher, H.: Immunological tolerance to LCMV antigens differently affects control of acute and chronic virus infection in mice. European Journal of Immunology 48, pp. 120 - 127 (2018)

Hirakawa, M.; Nagakubo, D.; Kanzler, B.; Avilov, S.; Krauth, B.; Happe, C.; Swann, J. B.; Nusser, A.; Boehm, T.: Fundamental parameters of the developing thymic epithelium in the mouse. Scientific Reports 8, p. 11095 (2018)

Holland, S. J.; Berghuis, L. M.; King, J. J.; Iyer, L. M.; Sikora, K.; Fifield, H.; Peter, S.; Quinlan, E. M.; Sugahara, F.; Shingate, P. et al.; Trancoso, I.; Iwanami, N.; Temereva, E.; Strohmeier, C.; Kuratani, S.; Venkatesh, B.; Evanno, G.; Aravind, L.; Schorpp, M.; Larijani, M.; Boehm, T.: Expansions, diversification, and interindividual copy number variations of AID/APOBEC family cytidine deaminase genes in lampreys. Proceedings of the National Academy of Sciences of the United States of America 115, pp. e3211 - e3220 (2018)

Krishnan, A.; Iyer, L. M.; Holland, S. J.; Boehm, T.; Aravind, L.: Diversification of AID/APOBEC-like deaminases in metazoa: multiplicity of clades and widespread roles in immunity. Proceedings of the National Academy of Sciences of the United States of America 115, pp. E3201 - E3210 (2018)

Tenno, M.; Kojo, S.; Lawir, D.-F.; Hess, I.; Shiroguchi, K.; Ebihara, T.; Endo, T. A.; Muroi, S.; Satoh, R.; Kawamoto, H. et al.; Boehm, T.; Taniuchi, I.: Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors. Journal of Experimental Medicine 215, pp. 595 - 610 (2018)

Boehm, T.; Hirano, M.; Holland, S. J.; Das, S.; Schorpp, M.; Cooper, M. D.: Evolution of Alternative Adaptive Immune Systems in Vertebrates. Annual Review of Immunology 36, pp. 19 - 42 (2018)

Nagakubo, D.; Krauth, B.; Boehm, T.: Genetic and non-genetic determinants of thymic epithelial cell number and function. Scientific Reports 7, 10314 (2017)

Swann, J.; Krauth, B.; Happe, C.; Boehm, T.: Cooperative interaction of BMP signalling and Foxn1 gene dosage determines the size fo the functionally active thymic epithelial compartment. Scientific Reports 7, pp. 8492 - 8496 (2017)

Swann, J.; Happe, C.; Boehm, T.: Elevated levels of Wnt signaling disrupt thymus morphogenesis and function. Scientific Reports 7, pp. 785 - 902 (2017)

Iwanami, N.; Hess, I.; Schorpp, M.; Boehm, T.: Studying the adaptive immune system in zebrafish by transplantation of hematopoietic precursor cells. Methods in Cell Biology 138, pp. 151 - 161 (2017)

Nagakubo, D.; Swann, J.; Birmelin, S.; Boehm, T.: Autoimmunity associated with chemically induced thymic dysplasia. International Immunology 29, pp. 385 - 390 (2017)

Iwanami, N.; Sikora, K.; Richter, A. S.; Mönnich, M.; Guerri, L.; Soza-Ried, C.; Lawir, D.-F.; Mateos, F.; Hess, I.; O’Meara, C. P. et al.; Schorpp, M.; Boehm, T.: Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development. Cell Reports 17, pp. 2259 - 2270 (2016)

Boehm, T.: Form follows function, function follows form: how lymphoid tissues enable and constrain immune reactions. Immunological Reviews 271, pp. 4 - 9 (2016)

Hess, I.; Boehm, T.: Stable mutlilineage xenogeneic replacement of definitive hematopoiesis in adult zebrafish. Scientific Reports 6, p. 19634 (2016)