Publications

2014

Journal Article

Braeutigam, C.; Rago, L.; Rolke, A.; Waldmeier, L.; Christofori, G.; Winter, J.: The RNA-binding protein Rbfox2: an essential regulator of EMT-driven alternative splicing and a mediator of cellular invasion. Oncogene 33, pp. 1082 - 1092 (2014)

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Cabezas-Wallscheid, N.; Klimmeck, D.; Hansson, J.; Lipka, D. B.; Reyes, A.; Wang, Q.; Weichenhan, D.; Lier, A.; von Paleske, L.; Renders, S. et al.; Wünsche, P.; Zeisberger, P.; Brocks, D.; Gu, L.; Herrmann, C.; Haas, S.; Essers, M. A.G.; Brors, B.; Trumpp, A.: Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis. Cell Stem Cell 15, pp. 507 - 522 (2014)

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Carnevalli, L. S.; Scognamiglio, R.; Cabezas-Wallscheid, N.; Rahmig, S.; Laurenti, E.; Masuda, K.; Jöckel, L.; Kuck, A.; Sujer, S.; Polykratis, A. et al.; Erlacher, M.; Pasparakis, M.; Essers, M. A.G.; Trumpp, A.: Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking Granzyme B. Journal of Experimental Medicine 211, pp. 769 - 779 (2014)

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Chelmicki, T.; Dündar, F.; Turley, M. J.; Khanam, T.; Aktas, T.; Ramírez, F.; Gendrel, A.-V.; Wright, P. R.; Videm, P.; Backofen, R. et al.; Heard, E.; Manke, T.; Akhtar, A.: MOF-associated complexes ensure stem cell identity and Xist repression. eLife 3, p. e02024 (2014)

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Di Cerbo, V.; Mohn, F.; Ryan, D. P.; Montellier, E.; Kacem, S.; Tropberger, P.; Kallis, E.; Holzner, M.; Hoerner, L.; Feldmann, A. et al.; Richter, F. M.; Bannister, A. J.; Mittler, G.; Michaelis, J.; Khochbin, S.; Feil, R.; Schuebeler, D.; Owen-Hughes, T.; Daujat, S.; Schneider, R.: Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription. eLife 3, pp. 1 - 23 (2014)

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Dias, J.; Van Nguyen, N.; Georgiev, P.; Gaub, A.; Brettschneider, J.; Cusack, S.; Kadlec, J.; Akhtar, A.: Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex. Genes and Development 28, pp. 929 - 942 (2014)

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Engelke, R.; Riede, J.; Hegermann, J.; Wuerch, A.; Eimer, S.; Dengjel, J.; Mitler, G.: The Quantitative Nuclear Matrix Proteome as a Biochemical Snapshot of Nuclear Organization. Journal of Proteome Research 13, pp. 3940 - 3956 (2014)

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Everts, B.; Pearce, E. J.: Metabolic Control of Dendritic Cell Activation and Function: Recent Advances and Clinical Implications. Frontiers in immunology 5, p. 203 (2014)

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Friedensohn, S.; Sawarkar, R.: Cis-regulatory variation: significance in biomedicine and evolution. Cell and Tissue Research 356, pp. 495 - 505 (2014)

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Gautier, E. L.; Ivanov, S.; Williams, J. W.; Huang, S. C.-C.; Marcelin, G.; Fairfax, K.; Wang, P. L.; Francis, J. S.; Leone, P.; Wilson, D. B. et al.; Artyomov, M. N.; Pearce, E. J.; Randolph, G. J.: Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival. Journal of Experimental Medicine 211, pp. 1525 - 1531 (2014)

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Gilsbach, R.; Preissl, S.; Grüning, B. A.; Schnick, T.; Burger, L.; Benes, V.; Würch, A.; Bönisch, U.; Günther, S.; Backofen, R. et al.; Fleischmann, B. K.; Schübeler, D.; Hein, L.: Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease. Nature Communications 5, pp. 1 - 13 (2014)

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Grosschedl, R.: Establishment and Maintenance of B cell Identity. Cold Spring Harbor Symposia on Quantitative Biology 78, pp. 23 - 30 (2014)

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Grötsch, B.; Brachs, S.; Lang, C.; Luther, J.; Derer, A.; Schlötzer-Schrehardt, U.; Bozec, A.; Fillatreau, S.; Berberich, I.; Hobeika, E. et al.; Reth, M.; Wagner, E. F.; Schett, G.; Mielenz, D.; David, J.-P.: The AP-1 transcription factor Fra1 ihhibits follicular B cell differentiation into plasma cells. The Journal of Experimental Medicine 211, pp. 2199 - 2212 (2014)

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Grün, D.; Kester, L.; van Oudenaarden, &. A.: Validation of noise models for single-cell transcriptomics enables genome-wiede quentification of stochastic gene expression. Nature methods 11, pp. 637 - 640 (2014)

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Grün, D.; Kirchner, M.; Thierfelder, N.; Stoeckius, M.; Selbach, M.; Rajewsky, N.: Conservation of mRNA and protein expression during development of C.elegans. Cell Reports 6, pp. 565 - 577 (2014)

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Hug, E.; Hobeika, E.; Reth, M.; Jumaa, H.: Inducible expression of hyperactive Syk in B cells activates Blimp-1-dependent terminal differentiation. Oncogene 33, pp. 3730 - 3741 (2014)

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Hutzler, S.; Özgör, L.; Naito-Matsui, Y.; Kläsener, K.; Winkler, T. H.; Reth, M.; Nitschke, L.: The Ligand-Binding Domain of Siglec-G Is Crucial for Its Selective Inhibitory Function on B1 Cells. The Journal of Immunology 192, pp. 5406 - 5414 (2014)

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Klasen, C.; Ohl, K.; Sternkopf, M.; Shachar, I.; Schmitz, C.; Heussen, N.; Hobeika, E.; Levit-Zerdoun, E.; Tenbrock, K.; Reth, M. et al.; Bernhagen, J.; El Bounkari, O.: MIF Promotes B Cell Chemotaxis through the Receptors CXCR4 and CD74 and ZAP-70 Signaling. The Journal of Immunology 192, pp. 5273 - 5284 (2014)

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Kläsener, K.; Maity, P. C.; Hobeika, E.; Yang, J.; Reth, M.: B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk. eLife 3, pp. 1 - 17 (2014)

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Klimmeck, D.; Cabezas-Wallscheid, N.; Reyes, A.; von Paleske, L.; Renders, S.; Hansson, J.; Krijgsveld, J.; Huber, W.; Trumpp, A.: Transcriptome-wide profiling and posttranscriptional analysis of hematopoietic stem/progenitor cell differentiation toward myeloid commitment. Stem Cell Reports 11, pp. 858 - 875 (2014)

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Königsberger, S.; Weis, V.; Prodöhl, J.; Stehling, M.; Hobeika, E.; Reth, M.; Kiefer, F.: Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms. European Journal of Immunology 45, pp. 603 - 611 (2014)

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Krönig, M.; Walter, M.; Drendel, V.; Werner, M.; Jilg, C. A.; Richter, A. S.; Backofen, R.; McGarry, D.; Follo, M.; Schultze-Seemann, W. et al.; Schüle, R.: Cell type specific gene expression analysis of prostate needle biopsies resolves tumor tissue heterogeneity. Oncotarget 6, pp. 1302 - 1314 (2014)

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Lämmermann, T.; Germain, R. N.: The multiple faces of leukocyte interstitial migration. Springer Seminars in Immunopathology 36, pp. 227 - 251 (2014)

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Lindner, J. M.; Kayo, H.; Hedlund, S.; Fukuda, Y.; Fukao, T.; Nielsen, P. J.: Cutting Edge: The Transcription Factor Bob1 Counteracts B Cell Activation and Regulates miR-146a in B cells. The Journal of Immunology 192, pp. 4483 - 4486 (2014)

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Lipka, D. B.; Wang, Q.; Cabezas-Wallscheid, N.; Klimmeck, D.; Weichenhan, D.; Herrmann, C.; Lier, A.; Brocks, D.; von Paleske, L.; Renders, S. et al.; Wünsche, P.; Zeisberger, P.; Gu, L.; Haas, S.; Essers, M. A.; Brors, B.; Eils, R.; Trumpp, A.; Milsom , M. D.; Plass, C.: Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing. Cell Cycle 13, pp. 3476 - 3487 (2014)

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Maity, P. C.; Yang, J.; Klaesener, K.; Reth, M.: The nanoscale organization of the B lymphocyte membrane. Biochemica et Biophiysica Acta 1853, pp. 830 - 840 (2014)

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Medgyesi, D.; Hobeika, E.; Biesen, R.; Kollert, F.; Taddeo, A.; Voll, R. E.; Hiepe, F.; Reth, M.: The protein tyrosine phsphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity. Journal of Experimental Medicine 211, pp. 427 - 440 (2014)

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Medgyesi, D.; Hobeika, E.; Biesen, R.; Kollert, F.; Taddeo, A.; Voll, R. E.; Hiepe, F.; Reth, M.: The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling an controls B cell autoimmunity. The Journal of Experimental Medicine 211, pp. 427 - 440 (2014)

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Nascimento, M.; Huang, S. C.; Smith, A.; Everts, B.; Lam, W.; Bassity, E.; Gautier, E. L.; Randolph, G. J.; Pearce, E. J.: Ly6C^hi Monocyte Recruitment is Responsible for Th2 Associated Host-Protective Maxrophage Accumulation in Liver Inflammation due to Schistosomiasis. PLoS Pathogens 10, p. e1004282 (2014)

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Okosun, J.; Bödör, C.; Wang, J.; Araf, S.; Yang, C.-Y.; Pan, C.; Boller, S.; Cittaro, D.; Bozek, M.; Iqbal, S. et al.; Matthews, J.; Wrench, D.; Marzec, J.; Tawana, K.; Popov, N.; O'riain, C.; O'Shea, D.; Carlotti, E.; Davies, A.; Lawrie, C. H.; Matolcsy, A.; Calaminici, M.; Norton, A.; Byers, R. J.; Mein, C.; Stupka, E.; Lister, T. A.; Lenz, G.; Montoto, S.; Gribben, J. G.; Fan, Y.; Grosschedl, R.; Chelala, C.; Fitzgibbon, J.: Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nature Genetics 46, pp. 176 - 181 (2014)

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Journal Article (74)