Publications

Lechner, A.; Henkel, F. D. R.; Hartung, F.; Bohnacker, S.; Alessandrini, F.; Gubernatorova, E. O.; Drutskaya, M. S.; Angioni, C.; Schreiber, Y.; Haimerl, P. et al.; Ge, Y.; Thomas, D.; Kabat, A. M.; Pearce, E. J.; Ohnmacht, C.; Nedospasov, S. A.; Murray, P. J.; Chaker, A. M.; Schmidt-Weber, C. B.; Bieren, J. E.-v.: Macrophages acquire a TNF-dependent inflammatory memory in allergic asthma. The journal of allergy and clinical immunology: official publication of the American Academy of Allergy, Asthma and Immunology 149, pp. 2078 - 2090 (2021)

Grande, F. D.; Jamilloux, V.; Choisne, N.; Calchera, A.; Rolshausen, G.; Petersen, M.; Schulz, M.; Nilsson, M. A.; Schmitt, I.: Transposable Elements in the Genome of the Lichen-Forming Fungus Umbilicaria pustulata and Their Distribution in Different Climate Zones along Elevation. Biology 11, 24 (2021)

Mossad, O.; Nent, E.; Woltemate, S.; Folschweiller, S.; Büscher, J. M.; Schnepf, D.; Erny, D.; Staeheli, P.; Bartos, M.; Szalay, A. et al.; Stecher, B.; Vital, M.; Sauer, J. F.; Lämmermann, T.; Prinz, M.; Blank, T.: Microbiota-dependent increase in δ-valerobetaine alters neuronal function and is responsible for age-related cognitive decline. Nature aging 1, pp. 1127 - 1136 (2021)

Willenborg, S.; Sanin, D. E.; Jais, A.; Ding, X.; Ulas, T.; Nüchel, J.; Popović, M.; MacVicar, T.; Langer, T.; Schultze, J. L. et al.; Gerbaulet, A.; Roers, A.; Pearce, E. J.; Brüning, J. C.; Trifunovic, A.; Eming, S. A.: Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing. Cell Metabolism 33, pp. 2398 - 2414 (2021)

Challen, G. A.; Pietras, E. M.; Cabezas-Wallscheid, N.; Signer, R. A. J.: Simplified murine multipotent progenitor isolation scheme: Establishing a consensus approach for multipotent progenitor identification. Experimental Hematology 104, pp. 55 - 63 (2021)

Fabri, M.; Villa, M.; Stanczak, M. A.; Edwards-Hicks, J.; Corrado, M.; Pearce, E. L.: Research Techniques Made Simple: Profiling Cellular Energy Metabolism. The Journal of Investigative Dermatology: Official Journal of the Society for Investigative Dermatology and the European Society for Dermatological Research 141, pp. 2767 - 2774 (2021)

Ibarra-Morales, D.; Rauer, M.; Quarato, P.; Rabbani, L.; Zenk, F.; Schulte-Sasse, M.; Cardamone, F.; Gomez-Auli, A.; Cecere, G.; Iovino, N.: Histone variant H2A.Z regulates zygotic genome activation. Nature Communications 12, 7002 (2021)

Petersen, M.; Winter, S.; Coimbra, R.; de Jong, M. J.; Kapitonov, V. V.; Nilsson, M. A.: Population analysis of retrotransposons in giraffe genomes supports RTE decline and widespread LINE1 activity in Giraffidae. Mobile DNA 12, 27 (2021)

Castro Alvarez, J. J.; Revel, M.; Carrasco Sala, J.; Cléard, F.; Pauli, D.; Hilgers, V.; Karch, F.; Maeda, R. K.: Repression of the Hox gene abd-A by ELAV-mediated Transcriptional Interference. PLoS Genetics 17 (11), e1009843 (2021)

Grzes, K. M.; Sanin, D. E.; Kabat, A. M.; Stanczak, M. A.; Edwards-Hicks, J.; Matsushita, M.; Hackl, A.; Hässler, F.; Knoke, K.; Zahalka, S. et al.; Villa, M.; Kofler, D. M.; Voll, R. E.; Zigrino, P.; Fabri, M.; Pearce, E. L.; Pearce, E. J.: Plasmacytoid dendritic cell activation is dependent on coordinated expression of distinct amino acid transporters. Immunity 54, pp. 2514 - 2530 (2021)

Roy, R.; Ramamoorthy, S.; Shapiro, B. D.; Kaileh, M.; Hernandez, D.; Sarantopoulou, D.; Arepalli, S.; Boller, S.; Singh, A.; Bektas, A. et al.; Kim, J.; Moore, A. Z.; Tanaka, T.; McKelvey, J.; Zukley, L.; Nguyen, C.; Wallace, T.; Dunn, C.; Wersto, R.; Wood, W.; Piao, Y.; Becker, K. G.; Coletta, C.; De, S.; Sen, J. M.; Battle, A.; Weng, N.-p.; Grosschedl, R.; Ferrucci, L.; Sen, R.: DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity. Immunity 54, pp. 2465 - 2480 (2021)

Lalioti, M.-E.; Rettkowski, J.; Cabezas-Wallscheid, N.: Avoid shocking your hematopoietic stem cells to keep them young and growing. Cell Stem Cell 28, pp. 1887 - 1889 (2021)

Frensch, M.; Jäger, C.; Müller, P. F.; Tadić, A.; Wilhelm, I.; Wehrum, S.; Diedrich, B.; Fischer, B.; Meléndez, A. V.; Dengjel, J. et al.; Eibel, H.; Römer, W.: Bacterial lectin BambL acts as a B cell superantigen. Cellular and Molecular Life Sciences 78, pp. 8165 - 8186 (2021)

Erny, D.; Dokalis, N.; Mezö, C.; Castoldi, A.; Mossad, O.; Staszewski, O.; Frosch, M.; Villa, M.; Fuchs, V.; Mayer, A. et al.; Neuber, J.; Sosat, J.; Tholen, S.; Schilling, O.; Vlachos, A.; Blank, T.; de Agüero, M. G.; Macpherson, A. J.; Pearce, E. J.; Prinz, M.: Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease. Cell Metabolism 33, pp. 2260 - 2276 (2021)

Llaó-Cid, L.; Roessner, P. M.; Chapaprieta, V.; Öztürk, S.; Roider, T.; Bordas, M.; Izcue, A.; Colomer, D.; Dietrich, S.; Stilgenbauer, S. et al.; Hanna, B.; Martín-Subero, J. I.; Seiffert, M.: EOMES is essential for antitumor activity of CD8⁺ T cells in chronic lymphocytic leukemia. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 35, pp. 3152 - 3162 (2021)

Pessoa Rodrigues, C.; Chatterjee, A.; Wiese, M.; Stehle, T.; Szymanski, W. G.; Shvedunova, M.; Akhtar, A.: Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice. Nature Communications 12, 6212 (2021)

O’Meara, C. P.; Guerri, L.; Lawir, D.-F.; Mateos, F.; Iconomou, M.; Iwanami, N.; Soza-Ried, C.; Sikora, K.; Siamishi, I.; Giorgetti, O. B. et al.; Peter, S.; Schorpp, M.; Boehm, T.: Genetic landscape of T cells identifies synthetic lethality for T-ALL. Communications Biology 4, 1201 (2021)

Bowman, T. V.; Trompouki, E.: Sensing Stemness. Current Stem Cell Reports 7, pp. 219 - 228 (2021)

Puri, D.; Koschorz, B.; Engist, B.; Onishi-Seebacher, M.; Ryan, D.; Soujanya, M.; Montavon, T.: Foxd3 controls heterochromatin-mediated repression of repeat elements and 2-cell state transcription. EMBO Reports 22, e53180 (2021)

Knoke, K.; Rongisch, R. R.; Grzes, K. M.; Schwarz, R.; Lorenz, B.; Yogev, N.; Pearce, E. L.; Pearce, E. J.; Kofler, D. M.; Fabri, M.: Tofacitinib Suppresses IL-10/IL-10R Signaling and Modulates Host Defense Responses in Human Macrophages. The Journal of Investigative Dermatology: Official Journal of the Society for Investigative Dermatology and the European Society for Dermatological Research 142, pp. 559 - 570 (2021)

Glaser, K. M.; Mihlan, M.; Lämmermann, T.: Positive feedback amplification in swarming immune cell populations. Current Opinion in Cell Biology 72, pp. 156 - 162 (2021)

Friedrich, C.; Taggenbrock, R. L. R. E.; Doucet-Ladevèze, R.; Golda, G.; Moenius, R.; Arampatzi, P.; Kragten, N. A. M.; Kreymborg, K.; de Agüero, M. G.; Kastenmüller, W. et al.; Saliba, A.-E.; Grün, D.; van Gisbergen, K. P. J. M.; Gasteiger, G.: Effector differentiation downstream of lineage commitment in ILC1s is driven by Hobit across tissues. Nature Immunology 22, pp. 1256 - 1267 (2021)

de Brito, T. F.; Coelho, V. L.; Cardoso, M. A.; de Brito, I. A. A.; Berni, M. A.; Zenk, F. L.; Iovino, N.; Pane, A.: Transovarial transmission of a core virome in the Chagas disease vector Rhodnius prolixus. PLoS Pathogens 17, e1009780 (2021)

Pessoa Rodrigues, C.; Akhtar, A.: Differential H4K16ac levels ensure a balance between quiescence and activation in hematopoietic stem cells. Science Advances 7 (32), eabi5987 (2021)

Puleston, D. J.; Baixauli, F.; Sanin, D. E.; Edwards-Hicks, J.; Villa, M.; Kabat, A. M.; Kamiński, M. M.; Stanckzak, M.; Weiss, H. J.; Grzes, K. M. et al.; Piletic, K.; Field, C. S.; Corrado, M.; Haessler, F.; Wang, C.; Musa, Y.; Schimmelpfennig, L.; Flachsmann, L.; Mittler, G.; Yosef, N.; Kuchroo, V. K.; Büscher, J. M.; Balabanov, S.; Pearce, E. J.; Green, D. R.; Pearce, E. L.: Polyamine metabolism is a central determinant of helper T cell lineage fidelity. Cell 184, pp. 4186 - 4202 (2021)

Wagner, A.; Wang, C.; Fessler, J.; DeTomaso, D.; Avila-Pacheco, J.; Kaminski, J.; Zaghouani, S.; Christian, E.; Thakore, P.; Schellhaass, B. et al.; Akama-Garren, E.; Pierce, K.; Singh, V.; Ron-Harel, N.; Douglas, V. P.; Bod, L.; Schnell, A.; Puleston, D.; Sobel, R. A.; Haigis, M.; Pearce, E. L.; Soleimani, M.; Clish, C.; Regev, A.; Kuchroo, V. K.; Yosef, N.: Metabolic modeling of single Th17 cells reveals regulators of autoimmunity. Cell 184, pp. 4168 - 4185 (2021)

Montavon, T.; Shukeir, N.; Erikson, G.; Engist, B.; Onishi-Seebacher, M.; Ryan, D.; Musa, Y.; Mittler, G.; Meyer, A. G.; Genoud, C. et al.; Jenuwein, T.: Complete loss of H3K9 methylation dissolves mouse heterochromatin organization. Nature Communications 12, 4359 (2021)

Keller Valsecchi, C. I.; Marois, E.; Basilicata, M. F.; Georgiev, P.; Akhtar, A.: Distinct mechanisms mediate X chromosome dosage compensation in Anopheles and Drosophila. Life science alliance 4, e202000996 (2021)

Barkaway, A.; Rolas, L.; Joulia, R.; Bodkin, J.; Lenn, T.; Owen-Woods, C.; Reglero-Real, N.; Stein, M.; Vázquez-Martínez, L.; Girbl, T. et al.; Poston, R. N.; Golding, M.; Saleeb, R. S.; Thiriot, A.; von Andrian, U. H.; Duchene, J.; Voisin, M.-B.; Bishop, C. L.; Voehringer, D.; Roers, A.; Rot, A.; Lämmermann, T.; Nourshargh, S.: Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Immunity 54, pp. 1494 - 1510 (2021)

Clapes, T.; Polyzou, A.; Prater, P.; Sagar; Morales-Hernández, A.; Ferrarini, M. G.; Kehrer, N.; Lefkopoulos, S.; Bergo, V.; Hummel, B. et al.; Obier, N.; Maticzka, D.; Bridgeman, A.; Herman, J. S.; Ilik, I.; Klaeylé, L.; Rehwinkel, J.; McKinney-Freeman, S.; Backofen, R.; Akhtar, A.; Cabezas-Wallscheid, N.; Sawarkar, R.; Rebollo, R.; Grün, D.; Trompouki, E.: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration. Nature Cell Biology 23, pp. 704 - 717 (2021)