Publications

Alotaibi, H.: The transcription factor ELF5 is essential for early preimplantation development. Molecular Biology Reports 50, pp. 2119 - 2125 (2022)

Hess, I.; Sagar; Meara, C. O.; Grün, D.; Schorpp, M.; Boehm, T.: Stage-specific and cell type-specific requirements of ikzf1 during haematopoietic differentiation in zebrafish. Scientific Reports 12, 21401 (2022)

Zolotarev, N.; Bayer, M.; Grosschedl, R.: EBF1 is continuously required for stabilizing local chromatin accessibility in pro-B cells. Proceedings of the National Academy of Sciences of the United States of America 119, e2210595119 (2022)

López, D. A.; Apostol, A. C.; Lebish, E. J.; Valencia, C. H.; Romero-Mulero, M. C.; Pavlovich, P. V.; Hernandez, G. E.; Forsberg, E. C.; Cabezas-Wallscheid, N.; Beaudin, A. E.: Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity. Cell Reports 41, 111677 (2022)

Glaser, K. M.; Tarrant, T. K.; Lämmermann, T.: Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions. Frontiers in immunology 13, 1039803 (2022)

Andreani, V.; Ramamoorthy, S.; Fässler, R.; Grosschedl, R.: Integrin β1 regulates marginal zone B cell differentiation and PI3K signaling. Journal of Experimental Medicine 220, e20220342 (2022)

Stanczak, M. A.; Mantuano, N. R.; Kirchhammer, N.; Sanin, D. E.; Jacob, F.; Coelho, R.; Everest-Dass, A. V.; Wang, J.; Trefny, M. P.; Monaco, G. et al.; Bärenwaldt, A.; Gray, M. A.; Petrone, A.; Kashyap, A. S.; Glatz, K.; Kasenda, B.; Normington, K.; Broderick, J.; Peng, L.; Pearce, O. M. T.; Pearce, E. L.; Bertozzi, C. R.; Zippelius, A.; Läubli, H.: Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade. Science translational medicine: integrating medicine and science / American Association for the Advancement of Science 14, eabj1270 (2022)

Zenke, S.; Sica, M. P.; Steinberg, F.; Braun, J.; Zink, A.; Gavrilov, A.; Hilger, A.; Arra, A.; Brunner-Weinzierl, M.; Elling, R. et al.; Beyersdorf, N.; Lämmermann, T.; Smulski, C. R.; Rohr, J. C.: Differential trafficking of ligands trogocytosed via CD28 versus CTLA4 promotes collective cellular control of co-stimulation. Nature Communications 13, 6459 (2022)

Carrasco, J.; Mateos, F.; Hilgers, V.: A critical developmental window for ELAV/Hu-dependent mRNA signatures at the onset of neuronal differentiation. Cell Reports 41, 111542 (2022)

Kabat, A. M.; Hackl, A.; Sanin, D. E.; Zeis, P.; Grzes, K. M.; Baixauli, F.; Kyle, R.; Caputa, G.; Edwards-Hicks, J.; Villa, M. et al.; Rana, N.; Curtis, J. D.; Castoldi, A.; Cupovic, J.; Dreesen, L.; Sibilia, M.; Pospisilik, J. A.; Urban Jr, J. F.; Grün, D.; Pearce, E. L.; Pearce, E. J.: Resident T_H2 cells orchestrate adipose tissue remodeling at a site adjacent to infection. Science Immunology 7, eadd3263 (2022)

Pittari, D.; Torre, M. D.; Borini, E.; Hummel, B.; Sawarkar, R.; Semino, C.; van Anken, E.; Panina-Bordignon, P.; Sitia, R.; Anelli, T.: CREB3L1 and CREB3L2 control Golgi remodelling during decidualization of endometrial stromal cells. Frontiers in Cell and Developmental Biology 10, 986997 (2022)

Moco, S.; Büscher, J. M.: Metabolomics: Going Deeper, Going Broader, Going Further. Methods in Molecular Biology 2554, pp. 155 - 178 (2022)

Nagel, M.; Labenz, C.; Dobbermann, H.; Czauderna, C.; Cabezas-Wallscheid, N.; Schattenberg, J. M.; Wörns, M. A.; Galle, P. R.; Marquardt, J. U.: Suppressed serological vitamin A in patients with liver cirrhosis is associated with impaired liver function and clinical detoriation. European journal of gastroenterology & hepatology: official journal of the European Association for Gastroenterology and Endoscopy 34, pp. 1053 - 1059 (2022)

Giorgetti, O. B.; Nusser, A.; Boehm, T.: Human thymoma-associated mutation of the GTF2I transcription factor impairs thymic epithelial progenitor differentiation in mice. Communications Biology 5, 1037 (2022)

Pagán, A. J.; Lee, L. J.; Edwards-Hicks, J.; Moens, C. B.; Tobin, D. M.; Busch-Nentwich, E. M.; Pearce, E. L.; Ramakrishnan, L.: mTOR-regulated mitochondrial metabolism limits mycobacterium-induced cytotoxicity. Cell 185, pp. 3720 - 3738.e13 (2022)

Baixauli, F.; Piletic, K.; Puleston, D. J.; Villa, M.; Field, C. S.; Flachsmann, L. J.; Quintana, A.; Rana, N.; Edwards-Hicks, J.; Matsushita, M. et al.; Stanczak, M. A.; Grzes, K. M.; Kabat, A. M.; Fabri, M.; Caputa, G.; Kelly, B.; Corrado, M.; Musa, Y.; Duda, K. J.; Mittler, G.; O'Sullivan, D.; Sesaki, H.; Jenuwein, T.; Büscher, J. M.; Pearce, E. J.; Sanin, D. E.; Pearce, E. L.: An LKB1-mitochondria axis controls T_H17 effector function. Nature 610, pp. 555 - 561 (2022)

Grzejda, D.; Mach, J.; Schweizer, J. A.; Hummel, B.; Rezansoff, A. M.; Eggenhofer, F.; Panhale, A.; Lalioti, M.-E.; Cabezas-Wallscheid, N.; Backofen, R. et al.; Felsenberg, J.; Hilgers, V.: The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity. Science Advances 8, eabo5578 (2022)

Bayer, M.; Boller, S.; Ramamoothy, S.; Zolotarev, N.; Cauchy, P.; Iwanami, N.; Mittler, G.; Boehm, T.; Grosschedl, R.: Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling. Genes and Development 36, pp. 901 - 915 (2022)

Cheng, P.; Zhao, X.; Katsnelson, L.; Camacho-Hernandez, E. M.; Mermerian, A.; Mays, J. C.; Lippman, S. M.; Rosales-Alvarez, R. E.; Moya, R.; Shwetar, J. et al.; Grun, D.; Fenyo, D.; Davoli, T.: Proteogenomic analysis of cancer aneuploidy and normal tissues reveals divergent modes of gene regulation across cellular pathways. eLife 11, e75227 (2022)

Yang, C.-H.; Fagnocchi, L.; Apostle, S.; Wegert, V.; Casaní-Galdón, S.; Landgraf, K.; Panzeri, I.; Dror, E.; Heyne, S.; Wörpel, T. et al.; Chandler, D. P.; Lu, D.; Yang, T.; Gibbons, E.; Guerreiro, R.; Bras, J.; Thomasen, M.; Grunnet, L. G.; Vaag, A. A.; Gillberg, L.; Grundberg, E.; Conesa, A.; Körner, A.; PERMUTE; Pospisilik, J. A.: Independent phenotypic plasticity axes define distinct obesity sub-types. Nature Metabolism 4, pp. 1150 - 1165 (2022)

Ho, J. N. H. G.; Schmidt, D.; Lowinus, T.; Ryoo, J.; Dopfer, E.-P.; Núñez, N. G.; Costa-Pereira, S.; Toffalori, C.; Punta, M.; Fetsch, V. et al.; Wertheimer, T.; Rittmann, M.-C.; Braun, L. M.; Follo, M.; Briere, C.; Vinnakota, J. M.; Langenbach, M.; Koppers, F.; Shoumariyeh, K.; Engel, H.; Rückert, T.; Märklin, M.; Holzmayer, S.; Illert, A. L.; Magon, F.; Andrieux, G.; Duquesne, S.; Pfeifer, D.; Staniek, J.; Rizzi, M.; Miething, C.; Köhler, N.; Duyster, J.; Menssen, H. D.; Boerries, M.; Büscher, J. M.; Cabezas-Wallscheid, N.; Blazar, B. R.; Apostolova, P.; Vago, L.; Pearce, E. L.; Becher, B.; Zeiser, R.: Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation. Blood 140, pp. 1167 - 1181 (2022)

Iwanami, N.; Petersen, M.; Diekhoff, D.; Boehm, T.: Clonal dynamics underlying the skewed CD4/CD8 ratio of mouse thymocytes revealed by TCR-independent barcoding. Communications Biology 5, 911 (2022)

Lenaerts, A.; Kucinski, I.; Deboutte, W.; Derecka, M.; Cauchy, P.; Manke, T.; Göttgens, B.; Grosschedl, R.: EBF1 primes B-lymphoid enhancers and limits the myeloid bias in murine multipotent progenitors. Journal of Experimental Medicine 219, e20212437 (2022)

Edwards-Hicks, J.; Su, H.; Mangolini, M.; Yoneten, K. K.; Wills, J.; Rodriguez-Blanco, G.; Young, C.; Cho, K.; Barker, H.; Muir, M. et al.; Guerrieri, A. N.; Li, X.-F.; White, R.; Manasterski, P.; Mandrou, E.; Wills, K.; Chen, J.; Abraham, E.; Sateri, K.; Qian, B.-Z.; Bankhead, P.; Arends, M.; Gammoh, N.; von Kriegsheim, A.; Patti, G. J.; Sims, A. H.; Acosta, J. C.; Brunton, V.; Kranc, K. R.; Christophorou, M.; Pearce, E. L.; Ringshausen, I.; Finch, A. J.: MYC sensitises cells to apoptosis by driving energetic demand. Nature Communications 13, 4674 (2022)

Nagakubo, D.; Hirakawa, M.; Iwanami, N.; Boehm, T.: Limits to in vivo fate changes of epithelia in thymus and parathyroid by ectopic expression of transcription factors Gcm2 and Foxn1. Scientific Reports 12, 13554 (2022)

Pitsillidou, C.; Alonso-Rubido, S.; Ávila-Ávila, A.; Romero-Mulero, M. C.; Labedz, A.; Oikonomou, A.; Proietti, L.; Psychoyiou, M. E.; Tellez-Quijorna, C.; Hillary, M. et al.; Fasouli, E. S.; Fernández-Rodríguez, G.; Giner-Laguarda, N.; Skinder, N.; Taroni, C.; Strouboulis, J.; Katsantoni, E.; Ronchi, A. E.: A Journey Into the Unknown: PhD Students in a European Training Network on Age-related Changes in Hematopoiesis Conduct Their Project During a Global Pandemic. HemaSphere: open access journal of the European Hematology Association 6, e763 (2022)

Asimi, V.; Kumar, A. S.; Niskanen, H.; Riemenschneider, C.; Hetzel, S.; Naderi, J.; Fasching, N.; Popitsch, N.; Du, M.; Kretzmer, H. et al.; Smith, Z. D.; Weigert, R.; Walther, M.; Mamde, S.; Meierhofer, D.; Wittler, L.; Buschow, R.; Timmermann, B.; Cissé, I. I.; Ameres, S. L.; Meissner, A.; Hnisz, D.: Hijacking of transcriptional condensates by endogenous retroviruses. Nature Genetics 54, pp. 1238 - 1247 (2022)

Schuster, E.-M.; Epple, M. W.; Glaser, K. M.; Mihlan, M.; Lucht, K.; Zimmermann, J. A.; Bremser, A.; Polyzou, A.; Obier, N.; Cabezas-Wallscheid, N. et al.; Trompouki, E.; Ballabio, A.; Vogel, J.; Büscher, J. M.; Westermann, A. J.; Rambold, A.: TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages. Nature Metabolism 4, pp. 856 - 866 (2022)

Mihlan, M.; Safaiyan, S.; Stecher, M.; Paterson, N.; Lämmermann, T.: Surprises from Intravital Imaging of the Innate Immune Response. Annual Review of Cell and Developmental Biology 38, pp. 18.1 - 18.23 (2022)

Zahalka, S.; Starkl, P.; Watzenboeck, M. L.; Farhat, A.; Radhouani, M.; Deckert, F.; Hladik, A.; Lakovits, K.; Oberndorfer, F.; Lassnig, C. et al.; Strobl, B.; Klavins, K.; Matsushita, M.; Sanin, D. E.; Grzes, K. M.; Pearce, E. J.; Gorki, A.-D.; Knapp, S.: Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling. Mucosal immunology: official journal of the Society for Mucosal Immunology 15, pp. 896 - 907 (2022)