Publications

Gronke, K.; Diefenbach, A.: Innate Immunity repairs gut lining. Nature 528, pp. 488 - 489 (2015)

Lupar, E.; Brack, M.; Garnier, L.; Laffont, S.; Rauch, K. S.; Schachtrup, K.; Arnold, S. J.; Guéry, J.-C.; Izcue, A.: Eomesodermin Expression in CD4⁺. The Journal of Immunology 195, pp. 4742 - 4752 (2015)

Grün, D.; van Oudenaarden, A.: Design and Analysis of Single-Cell Sequencing Experiments. Cell 163, pp. 799 - 810 (2015)

Cappadocia, L.; Pichler, A.; Lima, C. D.: Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase. Nature Structural & Molecular Biology 22 (12), pp. 968 - 975 (2015)

Eisenhardt, N.; Chaugule, V. K.; Koidl, S.; Droescher, M.; Dogan, E.; Rettich, J.; Sutinen, P.; Imanishi, S. Y.; Hofmann, K.; Palvimo, J. J. et al.; Pichler, A.: A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly. Nature Structural Molecular & Biology 22 (12), pp. 959 - 967 (2015)

Lempradl, A.; Pospisilik, J. A.; Penninger, J. M.: Exploring the emerging complexity in transcription regulation of energy homeostasis. Nature Reviews Genetics 16, pp. 665 - 681 (2015)

Cohen, I.; Rider, P.; Vornov, E.; Tomas, M.; Tudor, C.; Wegner, M.; Brondani, L.; Freudenberg, M.; Mittler, G.; Elisa, F.-M. et al.; Dinarello, C. A.; Apte, R. N.; Schneider, R.: IL-1α is a DNA damage sensor linking genetoxic stress signaling to sterile inflammation and innate immunity. Scientific Reports 5, pp. 1 - 11 (2015)

Leone, D. P.; Heavner, W. E.; Ferenczi, E. A.; Dobreva, G.; Huguendard, J. R.; Grosschedl, R.; McConnell, S. K.: Satb2 Regulates the differntiationof Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex. Cerebral Cortex 25, pp. 3406 - 3419 (2015)

Ramirez, F.; Lingg, T.; Toscano, S.; Lam, K.-C.; Georgiev, P.; Chung, H.-R.; Lajoie, B. R.; de Wit, E.; Zhan, Y.; de laat, W. et al.; Dekker, J.; Manke, T.; Akhtar, A.: High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila. Molecular Cell 60, pp. 146 - 162 (2015)

Bu, H.; Narisu, N.; Schlick, B.; Rainer, J.; Manke, T.; Schäfer, G.; Pasqualini, L.; Chines, P.; Schweiger, M. R.; Fuchsberger, C. et al.; Klocker, H.: Putative Prostate Cancer Risk SNP in an Androgen Receptor-Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites. Human Mutations 37, pp. 52 - 64 (2015)

Sahyoun, A. H.; Hölzer, M.; Jühling, F.; Höner zu Siederdissen, C.; Al-Arab, M.; Tout, K.; Marz, M.; Middendorf, M.; Stadler, P. F.; Bernt, M.: Towards a comprehensive picture of allo acceptor tRNA remolding in metazoan mitochondrial genomes. Nucleic Acids Research (London) 43, pp. 8044 - 8056 (2015)

Maity, P. C.; Blount, A.; Jumaa, H.; Ronneberger, O.; Lillemeier, B. F.; Reth, M.: B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation. Science Signaling 8, p. ra93 (2015)

Mayer, S. C.; Gilsbach, R.; Preissl, S.; Monroy Ordonoz, E. B.; Schnick, T.; Beetz, N.; Lother, A.; Rommel, C.; Ihle , H.; Bugger, H. et al.; Rühle, F.; Schrepper, A.; Schwarzer, M.; Heilmann, C.; Bönisch, U.; Gupta, S. K.; Wilpert, J.; Kretz, O.; von Elverfeldt, D.; Orth, J.; Aktories, K.; Beyersdorf, F.; Bode, C.; Krüger, M.; Thum, T.; Doenst, T.; Stoll, M.; Hein, L.: Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure. Circulation Research 117, pp. 622 - 633 (2015)

Chang, C.-H.; Qiu, J.; O'Sullivan, D.; Buck, M.; Noguchi, T.; Curtis, J. D.; Chen, Q.; Gindin, M.; Gubin, M. M.; van der Windt, G. J.W. et al.; Tonc, E.; Schreiber, R. D.; Pearce, E. J.; Pearce, E. L.: Metabolic Competition in the Tumor Microenvironment is a Driver of Cancer Progression. Cell 162, pp. 1229 - 1241 (2015)

Bremser, A.; Brack, M.; Izcue, A.: Higher Sensitivity of Foxp3⁺ Treg Compared to Foxp3^- Concentional T Cells to TCR-Independent Signals for CD69 Induction. PLoS One, p. e0137393 (2015)

Bremser, A.; Brack, M.; Izcue, A.: Higher Sensitivity of Foxp3⁺ Treg Compared to Foxp3^- Conventional T Cells to TCR-Independent Signals for CD69 Induction. Plos One 10, p. e0137393 (2015)

Fiala, G. J.; Janowska, I.; Prutek, F.; Hobeika, E.; Satapathy, A.; Sprenger, A.; Plum, T.; Seidl, M.; Dengjel, J.; Reth, M. et al.; Cesca, F.; Brummer, T.; Minguet, S.; Schamel, W. W. A.: Kidins220/ARMS binds to the B cell antigen recptor and regulates B cell development and activation. The Journal of Experimental Medicine 212 (10), pp. 1693 - 1708 (2015)

Buck, M. D.; O'Sullivan, D.; Pearce, E. L.: T cell metabolism drives immunity. Journal of Experimental Medicine 212, pp. 1345 - 1360 (2015)

Grün, D.; Lyubimova, A.; Kester, L.; Wiebrands, K.; Basak, O.; Sasaki, N.; Clevers, H.; van Oudenaarden, A.: Single-cell mRNA sequencing reveales rare intestinal cell types. Nature 525, pp. 251 - 255 (2015)

Hüttle, S.; Kläsener, K.; Schweizer, M.; Schneppenheim, J.; Oberg, H.-H.; Kabelitz, D.; Reth, M.; Saftig, P.; Schröder, B.: Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical for B Cell Receptor Signaling in Transitional B Cells. The Journal of Immunology 195, pp. 1548 - 1563 (2015)

Meunier, S.; Shvedunova, M.; Van Nguyen, N.; Avila, l.; Vernos, I.; Akhtar, A.: An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis. Nature Communications 6, 7889 (2015) (2015)

Ramachandran, H.; Herfurth, K.; Grosschedl, R.; Schäfer, T.; Walz, G.: SUMOylation Blocks the Ubiquitin-Mediated Degradatoin of the Nephronophthisis Gene Product Glis2/NPHP7. Plos One 10, e0130275 (2015)

Prasad, S.; Gaedicke, S.; Machein, M.; Mittler, G.; Braun , F.; Hettich, M.; Firat, E.; Klingner, K.; Schüler, J.; Wider, D. et al.; Wäsch, R. M.; Herold-Mende, C.; Elsässer-Beile, U.; Niedermann, G.: Effective Eradication of Gliioblastoma Stem Cells by Local Application of AC133/CD133-Specific T-cell Engaging Antibody and CD8 T Cells. Cancer research: an official organ of the American Association for Cancer Research 75, pp. 2166 - 2176 (2015)

Yamamoto, K.; Lee, B.J.; Li, C.; Dubois, R.L.; Hobeika, E.; Bhagat, G.; Zha, S.: Early B-cell-specific inactivation of ATM synergizes with ectopic CyclinD1 expression to promote pre-germinal center B-cell lymphomas in mice. Leukemia 29, pp. 1414 - 1424 (2015)

O'Sullivan, D.; Pearce, E. L.: Immunology, Expanding the roles of metabolism in T cells. Science 348, pp. 976 - 977 (2015)

Hernandez, P. P.; Mahlakoiv, T.; Yang, I.; Schwierzeck, V.; Nguyen, N.; Guendel, F.; Gronke, K.; Ryffel, B.; Hölscher, C.; Dumoutier, L. et al.; Renauld, J.-C.; Suerbaum, S.; Staehli, P.; Diefenbach, A.: Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection. Nature Immunology 16, pp. 698 - 707 (2015)

Chen, Z.; Shojaee, S.; Buchner, M.; Geng, H.; Lee, J. W.; Klemm, L.; Titz, B.; Graeber, T.; Park, E.; Tan, Y. X. et al.; Satterthwaite, A.; Paietta, E.; Hunger, S. P.; Willman, C. L.; Melnick, A.; Loh, M. L.; Jung, J. U.; Coligan, J. E.; Bolland, S.; Mak, T. W.; Limnander, A.; Jumaa, H.; Reth, M.; Weiss, A.; Lowell, C. A.; Müschen, M.: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature 521, pp. 357 - 361 (2015)

Tussiwand, R.; Everts, B.; Grajales-Reyes, G. E.; Kretzer, N. M.; Iwata, A.; Bagaitkar, J.; Wu, X.; Wong, R.; Anderson, D. A.; Murphy, T. L. et al.; Pearce, E. J.; Murphy, K. M.: Klf4 expression in conventional dendritic cells is required for T helper 2 cell responses. Immunity 42, pp. 916 - 928 (2015)

Trompouki, E.: Fish provide ID(H)eas on targeting leukemia. Blood 125, pp. 2880 - 2882 (2015)

Übelhart, R.; Hug, E.; Bach, M. P.; Wossning, T.; Dühren-von Minden, M.; Horn, A. H.C.; Tsiantoulas, D.; Kometani, K.; Kurosaki, T.; Binder, C. J. et al.; Sticht, H.; Nitschke, L.; Reth, M.; Jumaa, H.: Responsiveness of B cell is regulated by hinge region of IgD. Nature Immunology 16, pp. 534 - 543 (2015)