Journal Article (1538)

2021
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Knoke, K.; Rongisch, R. R.; Grzes, K. M.; Schwarz, R.; Lorenz, B.; Yogev, N.; Pearce, E. L.; Pearce, E. J.; Kofler, D. M.; Fabri, M.: Tofacitinib Suppresses IL-10/IL-10R Signaling and Modulates Host Defense Responses in Human Macrophages. The Journal of Investigative Dermatology: Official Journal of the Society for Investigative Dermatology and the European Society for Dermatological Research 142, pp. 559 - 570 (2021)
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Glaser, K. M.; Mihlan, M.; Lämmermann, T.: Positive feedback amplification in swarming immune cell populations. Current Opinion in Cell Biology 72, pp. 156 - 162 (2021)
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Friedrich, C.; Taggenbrock, R. L. R. E.; Doucet-Ladevèze, R.; Golda, G.; Moenius, R.; Arampatzi, P.; Kragten, N. A. M.; Kreymborg, K.; de Agüero, M. G.; Kastenmüller, W. et al.; Saliba, A.-E.; Grün, D.; van Gisbergen, K. P. J. M.; Gasteiger, G.: Effector differentiation downstream of lineage commitment in ILC1s is driven by Hobit across tissues. Nature Immunology 22, pp. 1256 - 1267 (2021)
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de Brito, T. F.; Coelho, V. L.; Cardoso, M. A.; de Brito, I. A. A.; Berni, M. A.; Zenk, F. L.; Iovino, N.; Pane, A.: Transovarial transmission of a core virome in the Chagas disease vector Rhodnius prolixus. PLoS Pathogens 17, e1009780 (2021)
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Pessoa Rodrigues, C.; Akhtar, A.: Differential H4K16ac levels ensure a balance between quiescence and activation in hematopoietic stem cells. Science Advances 7 (32), eabi5987 (2021)
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Puleston, D. J.; Baixauli, F.; Sanin, D. E.; Edwards-Hicks, J.; Villa, M.; Kabat, A. M.; Kamiński, M. M.; Stanckzak, M.; Weiss, H. J.; Grzes, K. M. et al.; Piletic, K.; Field, C. S.; Corrado, M.; Haessler, F.; Wang, C.; Musa, Y.; Schimmelpfennig, L.; Flachsmann, L.; Mittler, G.; Yosef, N.; Kuchroo, V. K.; Büscher, J. M.; Balabanov, S.; Pearce, E. J.; Green, D. R.; Pearce, E. L.: Polyamine metabolism is a central determinant of helper T cell lineage fidelity. Cell 184, pp. 4186 - 4202 (2021)
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Wagner, A.; Wang, C.; Fessler, J.; DeTomaso, D.; Avila-Pacheco, J.; Kaminski, J.; Zaghouani, S.; Christian, E.; Thakore, P.; Schellhaass, B. et al.; Akama-Garren, E.; Pierce, K.; Singh, V.; Ron-Harel, N.; Douglas, V. P.; Bod, L.; Schnell, A.; Puleston, D.; Sobel, R. A.; Haigis, M.; Pearce, E. L.; Soleimani, M.; Clish, C.; Regev, A.; Kuchroo, V. K.; Yosef, N.: Metabolic modeling of single Th17 cells reveals regulators of autoimmunity. Cell 184, pp. 4168 - 4185 (2021)
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Montavon, T.; Shukeir, N.; Erikson, G.; Engist, B.; Onishi-Seebacher, M.; Ryan, D.; Musa, Y.; Mittler, G.; Meyer, A. G.; Genoud, C. et al.; Jenuwein, T.: Complete loss of H3K9 methylation dissolves mouse heterochromatin organization. Nature Communications 12, 4359 (2021)
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Keller Valsecchi, C. I.; Marois, E.; Basilicata, M. F.; Georgiev, P.; Akhtar, A.: Distinct mechanisms mediate X chromosome dosage compensation in Anopheles and Drosophila. Life science alliance 4, e202000996 (2021)
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Barkaway, A.; Rolas, L.; Joulia, R.; Bodkin, J.; Lenn, T.; Owen-Woods, C.; Reglero-Real, N.; Stein, M.; Vázquez-Martínez, L.; Girbl, T. et al.; Poston, R. N.; Golding, M.; Saleeb, R. S.; Thiriot, A.; von Andrian, U. H.; Duchene, J.; Voisin, M.-B.; Bishop, C. L.; Voehringer, D.; Roers, A.; Rot, A.; Lämmermann, T.; Nourshargh, S.: Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Immunity 54, pp. 1494 - 1510 (2021)
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Clapes, T.; Polyzou, A.; Prater, P.; Sagar; Morales-Hernández, A.; Ferrarini, M. G.; Kehrer, N.; Lefkopoulos, S.; Bergo, V.; Hummel, B. et al.; Obier, N.; Maticzka, D.; Bridgeman, A.; Herman, J. S.; Ilik, I.; Klaeylé, L.; Rehwinkel, J.; McKinney-Freeman, S.; Backofen, R.; Akhtar, A.; Cabezas-Wallscheid, N.; Sawarkar, R.; Rebollo, R.; Grün, D.; Trompouki, E.: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration. Nature Cell Biology 23, pp. 704 - 717 (2021)
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Antonio Urrutia, G.; Ramachandran, H.; Cauchy, P.; Boo, K.; Ramamoorthy, S.; Boller, S.; Dogan, E.; Clapes, T.; Trompouki, E.; Torres-Padilla, M.-E. et al.; Palvimo, J. J.; Pichler, A.; Grosschedl, R.: ZFP451-mediated SUMOylation of SATB2 drives embryonic stem cell differentiation. Genes and Development 35, pp. 1143 - 1160 (2021)
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Onishi-Seebacher, M.; Erikson, G.; Sawitzki, Z.; Ryan, D.; Greve, G.; Lübbert, M.; Jenuwein, T.: Repeat to gene expression ratios in leukemic blast cells can stratify risk prediction in acute myeloid leukemia. BMC Medical Genomics 14, 166 (2021)
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Spiecker, L.; Witte, I.; Mehlig, J.; Shah, V.; Meyerhöfer, M.; Haehnel, P. S.; Petermann, V.; Schüler, A.; More, P.; Cabezas-Wallscheid, N. et al.; Horke, S.; Pautz, A.; Daiber, A.; Sasca, D.; Kindler, T.; Kleinert, a. H.: Deficiency of Antioxidative Paraoxonase 2 (Pon2) Leads to Increased Number of Phenotypic LT-HSCs and Disturbed Erythropoiesis. Oxidative medicine and cellular longevity, 3917028 (2021)
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Sommerkamp, P.; Cabezas-Wallscheid, N.; Trumpp, A.: Alternative Polyadenylation in Stem Cell Self-Renewal and Differentiation. Trends in Molecular Medicine 27, pp. 660 - 672 (2021)
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Kienle, K.; Glaser, K. M.; Eickhoff, S.; Mihlan, M.; Knöpper, K.; Reátegui, E.; Epple, M. W.; Gunzer, M.; Baumeister, R.; Tarrant, T. K. et al.; Germain, R. N.; Irimia, D.; Kastenmüller, W.; Lämmermann, T.: Neutrophils self-limit swarming to contain bacterial growth in vivo. Science 372, eabe7729 (2021)
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O'Sullivan, D.; Stanczak, M. A.; Villa, M.; Uhl, F. M.; Corrado, M.; Geltink, R. I. K.; Sanin, D. E.; Apostolova, P.; Rana, N.; Edwards-Hicks, J. et al.; Grzes, K. M.; Kabat, A. M.; Kyle, R. L.; Fabri, M.; Curtis, J. D.; Buck, M. D.; Patterson, A. E.; Regina, A.; Field, C. S.; Baixauli, F.; Puleston, D. J.; Pearce, E. J.; Zeiser, R.; Pearce, E. L.: Fever supports CD8+ effector T cell responses by promoting mitochondrial translation. Proceedings of the National Academy of Sciences of the United States of America 118, e2023752118 (2021)
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Sommerkamp, P.; Romero-Mulero, M. C.; Narr, A.; Ladel, L.; Hustin, L.; Schönberger, K.; Renders, S.; Altamura, S.; Zeisberger, P.; Jäcklein, K. et al.; Klimmeck, D.; Rodriguez-Fraticelli, A.; Camargo, F. D.; Perié, L.; Trumpp, A.; Cabezas-Wallscheid, N.: Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells. Blood 137, pp. 3218 - 3224 (2021)
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Bousounis, P.; Bergo, V.; Trompouki, E.: Inflammation, Aging and Hematopoiesis: A Complex Relationship. Cells 10, 1386 (2021)
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Duda, K. J.; Ching, R. W.; Jerabek, L.; Shukeir, N.; Erikson, G.; Engist, B.; Onishi-Seebacher, M.; Perrera, V.; Richter, F.; Mittler, G. et al.; Fritz, K.; Helm, M.; Knuckles, P.; Bühler, M.; Jenuwein, T.: m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA:DNA hybrid formation in mouse heterochromatin. Nucleic Acids Research (London) 49, pp. 5568 - 5587 (2021)
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Groß, M.; Speckmann, C.; May, A.; Gajardo-Carrasco, T.; Wustrau, K.; Maier, S. L.; Panning, M.; Huzly, D.; Agaimy, A.; Bryceson, Y. T. et al.; Choo, S.; Chow, C. W.; Dückers, G.; Fasth, A.; Fraitag, S.; Gräwe, K.; Haxelmans, S.; Holzinger, D.; Hudowenz, O.; Hübschen, J.; Khurana, C.; Kienle, K.; Klifa, R.; Korn, K.; Kutzner, H.; Lämmermann, T.; Ledig, S.; Lipsker, D.; Meeths, M.; Naumann-Bartsch, N.; Rascon, J.; Schänzer, A.; Seidl, M.; Tesi, B.; Vauloup-Fellous, C.; Vollmer-Kary, B.; Warnatz, K.; Wehr, C.; Neven, B.; Vargas, P.; Sepulveda, F. E.; Lehmberg, K.; Schmitt-Gräff, A.; Ehl, S.: Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity. The journal of allergy and clinical immunology: official publication of the American Academy of Allergy, Asthma and Immunology 149, pp. 388 - 399 (2021)
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Arasa, J.; Collado-Diaz, V.; Kritikos, I.; Medina-Sanchez, J. D.; Friess, M. C.; Sigmund, E. C.; Schineis, P.; Hunter, M. C.; Tacconi, C.; Paterson, N. et al.; Nagasawa, T.; Kiefer, F.; Makinen, T.; Detmar, M.; Moser, M.; Lämmermann, T.; Halin, C.: Upregulation of VCAM-1 in lymphatic collectors supports dendritic cell entry and rapid migration to lymph nodes in inflammation. Journal of Experimental Medicine 218, p. e20201413 (2021)
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Zenk, F.; Zhan, Y.; Kos, P.; Löser, E.; Atinbayeva, N.; Schächtle, M.; Tiana, G.; Giorgetti, L.; Iovino, N.: HP1 drives de novo 3D genome reorganization in early Drosophila embryos. Nature 593, pp. 289 - 293 (2021)
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Tiago, T.; Hummel, B.; Morelli, F. F.; Basile, V.; Vinet, J.; Galli, V.; Mediani, L.; Antoniani, F.; Pomella, S.; Cassandri, M. et al.; Garone, M. G.; Silvestri, B.; Cimino, M.; Cenacchi, G.; Costa, R.; Mouly, V.; Poser, I.; Yeger-Lotem, E.; Rosa, A.; Alberti, S.; Rota, R.; Ben-Zvi, A.; Sawarkar, R.; Carra, S.: Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor. Cell Death and Disease 12, 452 (2021)
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Dudek, M.; Pfister, D.; Donakonda, S.; Filpe, P.; Schneider, A.; Laschinger, M.; Hartmann, D.; Hüser, N.; Meiser, P.; Bayerl, F. et al.; Inverso, D.; Wigger, J.; Sebode, M.; Öllinger, R.; Rad, R.; Hegenbarth, S.; Anton, M.; Guillot, A.; Bowman, A.; Heide, D.; Müller, F.; Ramadori, P.; Leone, V.; Garcia-Caceres, C.; Gruber, T.; Seifert, G.; Kabat, A.; Malm, J.-P.; Reider, S.; Effenberger, M.; Roth, S.; Billeter, A. T.; Müller-Stich, B.; Pearce, E. J.; Koch-Nolte, F.; Käser, R.; Tilg, H.; Thimme, R.; Böttler, T.; Tacke, F.; Dufour, J.-F.; Haller, D.; Murray, P. J.; Heeren, R.; Zehn, D.; Böttcher, J. P.; Knolle, M. H. P. A.: Auto-aggressive CXCR6 CD8 T cells cause liver immune pathology in NASH. Nature 592, pp. 444 - 449 (2021)
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Akerman, I.; Maestro, M. A.; Franco, E. D.; Grau, V.; Flanagan, S.; García-Hurtado, J.; Mittler, G.; Ravassard, P.; Piemonti, L.; Ellard, S. et al.; Hattersley, A. T.; Ferrer, J.: Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene. Cell Reports 35, 108981 (2021)
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Villa, M.; O'Sullivan, D.; Pearce, E. L.: Glucose makes Treg lose their temper. Cancer Cell 39, pp. 460 - 462 (2021)
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Stanczak, M. A.; Sanin, P. D. E.; Apostolova, P.; Nerz, G.; Lampaki, D.; Hofmann, M.; Steinmann, D.; Krohn-Grimberghe, M.; Thimme, R.; Mittler, G. et al.; Waller, C. F.; Pearce, E. J.; Pearce, E. L.: IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals. Nature Communications 12, 2133 (2021)
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Mohr, T.; Katz, S.; Paulitschke, V.; Aizarani, N.; Tolios, A.: Systematic Analysis of the Transcriptome Profiles and Co-Expression Networks of Tumour Endothelial Cells Identifies Several Tumour-Associated Modules and Potential Therapeutic Targets in Hepatocellular Carcinoma. Cancers / Molecular Diversity Preservation International (MDPI) 13, 1768 (2021)
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Schoels, M.; Zhuang, M.; Fahrner, A.; Kuechlin, S.; Sagar, S.; Franz, H.; Schmitt, A.; Walz, G.; Yakulov, T. A.: Single-cell mRNA profiling reveals changes in solute carrier expression and suggests a metabolic switch during zebrafish pronephros development. American Journal of Physiology-Renal Physiology 320, pp. F826 - F837 (2021)
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