SGS: Henrik Kaessmann - The origins and evolution of amniote sex chromosomes

The Kaessmann lab focuses on mammalian and vertebrate organ origins and evolution, exploring genomic and molecular changes. Their research includes analyzing extensive genomics datasets, like RNA-seq, from a vast organ collection. This has led to discoveries about the evolution of protein-coding genes, alternative splicing, long noncoding RNAs, microRNAs, and sex chromosomes, and their phenotypic effects across species. Recently, they've employed single-cell genomics and bioinformatics to study individual cells. Current major projects examine vertebrate brain evolution, including tissues and cells from various vertebrates, from sea lampreys to humans. Additional studies are underway on the evolution and development of gonads, liver, intestine, and the placenta in mammals.