Max-Planck-Institut für Immunbiologie und Epigenetik

Publikationen von Erika L. Pearce

Alle Typen

Zeitschriftenartikel (89)

2016

Zeitschriftenartikel

Buck, M. D.; O’Sullivan, D.; Geltink, R. I. K.; Curtis, J. D.; Chang, C.-H.; Sanin, D. E.; Qiu, J.; Kretz, O.; Braas, D.; van der Windt, G. J.W. et al.; Chen, Q.; Huang, S. C.-C.; O’Neill, C. M.; Edelson, B. T.; Pearce, E. J.; Sesaki, H.; Huber, T. B.; Rambold, A.; Pearce, E. L.: Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming. Cell 166, S. 63 - 76 (2016)

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Zeitschriftenartikel

Kaiko, G. E.; Ryu, S. H.; Koues, O. I.; Collins, P. L.; Solnica-Krezel, L.; Pearce, E. J.; Pearce, E. L.; Oltz, E. M.; Stappenbeck, T. S.: The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites. Cell 167, S. 1708 - 1720 (2016)

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Zeitschriftenartikel

Monticelli, L. A.; Buck, M. D.; Flamar, A.-L.; Saenz, S. A.; Wojno, E. D. T.; Yudanin, N. A.; Osborne, L. C.; Hepworth, M. R.; Tran, S. V.; Rodewald, H.-R. et al.; Shah, H.; Cross, J. R.; Diamond, J. M.; Cantu, E.; Christie, J. D.; Pearce, E. L.; Artis, D.: Arginase 1 is an innate lymphoid-cell intrinisic metabolic checkpoint controlling type 2 inflammation. Nature Immunology 17, S. 656 - 665 (2016)

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Zeitschriftenartikel

Chang, C.-H.; Pearce, E. L.: Emerging concepts of T cell metabolism as a target of immunotherapy. Nature Immunology 17, S. 364 - 368 (2016)

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Zeitschriftenartikel

van der Windt, G. J.W.; Chang, C.; Pearce, E. L.: Measuring Bioenergetics in T Cells Using a Seahorse Extracellular Flux Analyzer. Current Protocols in Immunology 113, S. 16B1.3 - 16B.14 (2016)

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2015

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Chang, C.-H.; Qiu, J.; O'Sullivan, D.; Buck, M.; Noguchi, T.; Curtis, J. D.; Chen, Q.; Gindin, M.; Gubin, M. M.; van der Windt, G. J.W. et al.; Tonc, E.; Schreiber, R. D.; Pearce, E. J.; Pearce, E. L.: Metabolic Competition in the Tumor Microenvironment is a Driver of Cancer Progression. Cell 162, S. 1229 - 1241 (2015)

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Zeitschriftenartikel

Buck, M. D.; O'Sullivan, D.; Pearce, E. L.: T cell metabolism drives immunity. Journal of Experimental Medicine 212, S. 1345 - 1360 (2015)

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publisher-version

Zeitschriftenartikel

O'Sullivan, D.; Pearce, E. L.: Immunology, Expanding the roles of metabolism in T cells. Science 348, S. 976 - 977 (2015)

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Zeitschriftenartikel

O'Sullivan, D.; Pearce, E. L.: Targeting T cell metabolism for therapy. Trends in Immunology 36, S. 71 - 80 (2015)

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Zeitschriftenartikel

Blagih, J.; Coulombe, F.; Vincent, E. E.; Dupuy, F.; Galicia-Vázquez, G.; Yurchenko, E.; Raissi, T. C.; van der Windt, G. J.W.; Viollet, B.; Pearce, E. L. et al.; Pelletier, J.; Piccirillo, C. A.; Krawczyk, C. M.; Divangahi, M.; Jones, R. G.: The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vitro. Immunity 42, S. 41 - 54 (2015)

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2014

Zeitschriftenartikel

Xu, X.; Araki, K.; Li, S.; Han, J.-H.; Ye, L.; Tan, W. G.; Konieczny, B. T.; Bruinsma, M. W.; Martinez, J.; Pearce, E. L. et al.; Green, D. R.; Jones, D. P.; Virgin, H. W.; Ahmed, R.; Xu, X.; Araki, K.; Li, S.; Han, J.-H.; Ye, L.; Tan, W. G.; Konieczny, B. T.; Bruinsma, M. W.; Martinez, J.; Pearce, E. L.; Green, D. R.; Jones, D. P.; Ahmed, R.: Autophagy is essential for effector CD8⁺ T cell survival and memory formation. Nature Immunology 15, S. 1152 - 1161 (2014)

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Zeitschriftenartikel

O'Sullivan, D.; Pearce, E. L.: Fatty acid sysnthesis tips the TH17-Treg cell balance. Nature Medicine 20, S. 1235 - 1236 (2014)

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Zeitschriftenartikel

Walsh, M. C.; Pearce, E. L.; Cejas, P. J.; Lee, J.; Wang, L.-S.; Choi, Y.: IL-18 synergivzes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals. The Journal of Immunology 193, S. 3992 - 4001 (2014)

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Zeitschriftenartikel

Amiel, E.; Everts, B.; Fritz, D.; Beauchamp, S.; Ge, B.; Pearce, E. L.; Pearce, E. J.: Mechanistic target of rapamycin inhition extend cellular lifespan in dendritic cells by preserving mitochondrial function. The Journal of Immunology 193, S. 2821 - 2830 (2014)

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Zeitschriftenartikel

Chou, C.; Pinto, A. K.; Jonathen, C.; Persaud, S. P.; Cella, M.; Lin, C.-C.; Edelson, B. T.; Allen, P. M.; Colonna, M.; Pearce, E. L. et al.; Diamond, M. S.; Egawa, T.: c-Myc-induced transcription factor AP4 is requeired for host protection mediated by CD8⁺ T Cells. Nature Immunology 15, S. 884 - 893 (2014)

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Zeitschriftenartikel

Huang, S. C.-C.; Everts, B.; Ivanova, Y.; O'Sullivan, D.; Nascimento, M.; Smith, A. M.; Beatty, W.; Love-Gregory, L.; Lam, W. Y.; O'Neill, C. M. et al.; Yan, C.; Du, H.; Abumrad, N. A.; Urban, J. F. J.; Artyomov, M. N.; Pearce, E. J.; Pearce, E. L.: Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages. Nature Immunology 15, S. 846 - 855 (2014)

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Zeitschriftenartikel

O'Sullivan, D.; van der Windt, G. J.W.; Huang, S. C.-C.; Curtis , J.; Chang, C.-H.; Buck, M. D.; Qiu, J.; Smith, A. M.; Lam, W. Y.; DiPlato, L. M. et al.; Hsu, F.-F.; Birnbaum, M. J.; Pearce, E. J.; Pearce, E. L.: Memory CD8⁺ T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development. Immunity 41, S. 75 - 88 (2014)

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Zeitschriftenartikel

Everts, B.; Amiel, E.; Huang, S. C.-C.; Smith, A. M.; Chang, C.-H.; Lam, W. Y.; Redmann, V.; Freitas, T. C.; Blagih, J.; van der Windt, G. J. W. et al.; Artyomov, M. N.; Jones, R. G.; Pearce, E. L.; Pearce, E. J.: TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation. Nature Immunology 15, S. 323 - 332 (2014)

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2013

Zeitschriftenartikel

Pearce, E. L.; Poffenberger, M. C.; Chang, C.-H.; Jones, R. G.: Fueling immunity: insights into metabolism and lymphocyte function. Science 342, S. 1242454 (2013)

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Zeitschriftenartikel

van der Windt, G. J. W.; O’Sullivan, D.; Everts, B.; Huang, S. C.-C.; Buck, M. D.; Curtis, J. D.; Chang, C.-H.; Smith, A. M.; Ai, T.; Faubert, B. et al.; Jones, R. G.; Pearce, E. J.; Pearce, E. L.: CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability. Proceedings of the National Academy of Sciences of the United States of America 153, S. 1239 - 1259 (2013)

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Zeitschriftenartikel

Chang, C.-H.; Curtis, J. D.; Maggi Jr., L. B.; Faubert, B.; Villarino, A. V.; O’Sullivan, D.; Huang, S. C.-C.; van der Windt, G. J.W.; Blagih, J.; Qiu, J. et al.; Weber, J. D.; Pearce, E. J.; Jones, R. G.; Pearce, E. L.: Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell 153, S. 1239 - 1251 (2013)

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Zeitschriftenartikel

Pearce, E. L.; Pearce, E. J.: Metabolic pathways in immune cell activation and quiscence. Immunity 38, S. 633 - 643 (2013)

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2012

Zeitschriftenartikel

van der Windt , G. J. W.; Pearce, E. L.: Metabolic switching and fuel choice during T-cell differentiation and memory development. Immunological Reviews 249, S. 27 - 42 (2012)

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Zeitschriftenartikel

Amiel, E.; Everts, B.; Freitas, T. C.; King, I. L.; Curtis, J. D.; Pearce, E. L.; Pearce, E. J.: Inhibition of mechanistic target of repamycin promotes dendritic cell activation and enhances therapeutic autologous vaccination in mice. The Journal of Immunology 189, S. 2151 - 2158 (2012)

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Zeitschriftenartikel

Everts, B.; Amiel, E.; van der Windt, G. J. W.; Freitas, T. C.; Chott, R.; Yarasheski, K. E.; Pearce, E. L.; Pearce, E. J.: Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells. Blood 120, S. 1422 - 1431 (2012)

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Zeitschriftenartikel

Cejas, P. J.; Walsh, M. C.; Pearce, E. L.; Han, D.; Harms, G. M.; Artis, D.; Turka, L. A.; Choi, Y.: TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2. Blood 115, S. 4750 - 4757 (2012)

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Zeitschriftenartikel

van der Windt, G. J.W.; Everts, B.; Chang, C.-H.; Curtis, J. D.; Freitas, T. C.; Amiel, E.; Pearce, E. J.; Pearce, E. L.: Mitochondrial respiratory capacity is a critical regulator of CD8⁺ T cell memory development. Immunity 36, S. 68 - 78 (2012)

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Zeitschriftenartikel

Huang, S. C.-C.; Freitas, T. C.; Amiel, E.; Everts, B.; Pearce, E. L.; Lok, J. B.; Pearce, E. J.: Fatty acid oxidation is essential for egg production by the parasitic flatworm Schistosoma mansoni. PLoS Pathogens 8, S. e1002996 (2012)

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2010

Zeitschriftenartikel

Pearce, E. L.: Metabolism in T cell activation and differentiation. Current Opinion in Immunology 22, S. 314 - 320 (2010)

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