Publications

Journal Article (1282)

  1. 2020
    Journal Article
    Gaub, A.; Sheikh, B. N.; Basilicata, M. F.; Vincent, M.; Nizon, M.; Colson, C.; Bird, M. J.; Bradner, J. E.; Thevenon, J.; Boutros, M. et al.; Akhtar, A.: Evolutionary conserved NSL complex/BRD4 axis controls transcription activation via histone acetylation. Nature Communications 11, p. 2243 (2020)
  2. Journal Article
    Grün, D.: Revealing dynamics of gene expression variability in cell state space. Nature methods, pp. 45 - 49 (2020)
  3. Journal Article
    Lawir, D.-F.; Hess, I.; Sikora, K.; Iwanami, N.; Siamishi, I.; Schorpp, M.; Boehm, T.: Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development. Proceedings of the National Academy of Sciences of the United States of America (2020)
  4. Journal Article
    Ramamoorthy, S.; Kometani, K.; Herman, J. S.; Bayer, M.; Boller, S.; Edwards-Hicks, J.; Ramachandran, H.; Li, R.; Klein-Geltink, R.; Pearce, E. L. et al.; Grün, D.; Grosschedl, R.: EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism. Genes and Development 34, pp. 1503 - 1519 (2020)
  5. Journal Article
    Rodrigues, C. P.; Herman, J. S.; Herquel, B.; Velsecchi Keller, C. I.; Stehle, T.; Grün, D.; Akhtar, A.: Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate. Science Advances 6, p. eaaz4815 (2020)
  6. Journal Article
    Sagar, S.; Pokrovskii, M.; Herman, J. S.; Naik, S.; Sock, E.; Zeis, P.; Lausch, U.; Wegner, M.; Tanriver, Y.; Littman, D. R. et al.; Grün, D.: Deciphering the regulatory landscapte of fetal and adult γδ T-cell development at single-cell resolution. The EMBO Journal 39, p. e104159 (2020)
  7. Journal Article
    Walther, M.; Schrahn, S.; Krauss, V.; Lein, S.; Kessler, J.; Jenuwein, T.; Reuter, G.: Heterochromatin formation in Drosophila requires genome-wide histone deacetylation in cleavage chromatin before mid-blastula transition in early embryogenesis. Chromosoma: Biology of the Nucleus 129, pp. 83 - 98 (2020)
  8. 2019
    Journal Article
    Sankowski, R.; Böttcher, C.; Masuda, T.; Geirsdottir, L.; Sagar, S.; Sindram, E.; Seredenina, T.; Muhs, A.; Scheiwe, C.; Shah, M. J. et al.; Heiland, D. H.; Schnell, O.; Grün, D.; Priller, J.; Prinz, M.: Mapping microglia states in teh human brain through the integration of high-dimensional techniques. Nature Neuroscience 22, pp. 2098 - 2110 (2019)
  9. Journal Article
    Sheikh, B. N.; Bondareva, O.; Guhathakurta, S.; Tsang, T. H.; Sikora, K.; Aizarani, N.; Sagar, S.; Holz, H.; Grün, D.; Hein, L. et al.; Akhtar, A.: Systematic Identification of Cell-Cell Communication Networks in the Developing Brain. iScience 21, pp. 273 - 287 (2019)
  10. Journal Article
    Grün, D.: Revealing dynamics of gene expression variability in cell state space. Nature methods (2019)
  11. Journal Article
    Antonova, A.; Hummel, B.; Khavaran, A.; Redhaber, D. M.; Aprile-Garcia, F.; Rawat, P.; Gundel, K.; Schneck, M.; Hansen, E. C.; Mitschke, J. et al.; Mittler, G.; Miething, C.; Sawarkar, R.: Heat-Shock Protein 90 Controls the Expression of Cell-Cycle Genes by Stabilizing Metazoan-Specific Host-Cell Factor HCFC1. Cell Reports 29, pp. 1645 - 1659 (2019)
  12. Journal Article
    Saçma, M.; Pospiech, J.; Bogeska, R.; de Back, W.; Mallm, J.-P.; Sakk, V.; Soller, K.; Marka, G.; Vollmer, A.; Karns, R. et al.; Cabezas-Wallscheid, N.; Trumpp, A.; Méndez-Ferrer, S.; Milsom, M. D.; Mulaw, M. A.; &, H. G.; Florian, M. C.: Haematopoietic stem cells in perisinusoidal niches are protected from ageing. Nature Cell Biology 21, pp. 1309 - 1320 (2019)
  13. Journal Article
    Karoutas, A.; Szymanski, W.; Rausch, T.; Guhathakurta, S.; Rog-Zielinska, E. A.; Peyronnet, R.; Seyfferth, J.; Chen, H.-R.; de Leeuw, R.; Herquel, B. et al.; Kimura, H.; Mittler, G.; Kohl, P.; Medalia, O.; Korbel, J. O.; Akhtar, A.: The NSL complex maintains nuclear architecture stability via lamin A/C acetylation. Nature Cell Biology 21, pp. 1248 - 1260 (2019)
  14. Journal Article
    O'Sullivan, D.: The metabolic spectrum of memory T cells. Immunology and Cell Biology 97, pp. 636 - 646 (2019)
  15. Journal Article
    Bhardwaj, V.; Semplicio, G.; Erdogdu, N. U.; Manke, T.; Akhtar, A.: MapCap allows high-resolution detection and differential expression analysis of transcription start sites. Nature Communications 10, p. 3219 (2019)
  16. Journal Article
    Aizarani, N.; Saviano, A.; Sagar, S.; Mailly , L.; Durand, S.; Herman, J. S.; Pessaux, P.; Baumert , T. F.; Grün, D.: A human liver cell atlas reveals heterogeneity and epithelial progenitors. Nature 572, pp. 199 - 204 (2019)
  17. Journal Article
    Uderhardt, S.; Martins, A. J.; Tsang, J. S.; Lämmermann, T.; Germain, R. N.: Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage. Cell 177, pp. 541 - 555 (2019)
  18. Journal Article
    Klein-Geltink, R.; Pearce , E. L.: The Importance of methionine metabolism. eLife 8, p. e47221 (2019)
  19. Journal Article
    O'Sullivan, D.; Sanin, P. D. E.; Pearce, E. J.; Pearce, E. L.: Metabolic interventions in the immune response to cancer. Nature Reviews Immunology 19, pp. 324 - 334 (2019)
  20. Journal Article
    Cameron, A. M.; Castoldi, A.; Sanin, D. E.; Flachsmann, L. J.; Field, C. S.; Puleston, D. J.; Kyle, R. L.; Patterson, A.; Hassler, F.; Buescher, J. M. et al.; Kelly, B.; Pearce, E. L.; Pearce, E. J.: Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species-mediated DNA damage. Nature Immunology 20, pp. 420 - 432 (2019)
  21. Journal Article
    Hörner, M.; Raute, K.; Hummel, B.; Madl, J.; Creusen, G.; Thomas, O. S.; Christen, E. H.; Hotz, N.; Gübeli, R. J.; Engesser, R. et al.; Rebmann, B.; Lauer, J.; Rolauffs, B.; Timmer, J.; Schamel, W. W. A.; Pruszak, J.; Römer, W.; Zurbriggen, M. D.; Friedrich, C.; Walther, A.; Minguet, S.; Sawarkar, R.; Weber, W.: Phytochrome-Based Extracellular Matrix with Reversibly Tunable mechanical Properties. Advanced Materials, p. e1806727 (2019)
  22. Journal Article
    Mateo, V.; Baixauli Celda, F.; Pearce, E. L.: Potassium shapes antitumor immunity. Science 363, pp. 1395 - 1396 (2019)
  23. Journal Article
    Lam, K.-C.; Chung, H.-R.; Semplicio, G.; Iyer, S. S.; Gaub, A.; Bhardwaj, V.; Holz, H.; Georgiev, P.; Akhtar, A.: The NSL complex-mediated nucleosome landscape is required to maintain transcription fidelity and suppression of transcription noise. Genes and Development 33, pp. 453 - 465 (2019)
  24. Journal Article
    Wilhelm, I.; Levit-Zerdoun, E.; Jakob, J.; Villringer, S.; Frensch, M.; Übelhart, R.; Landi, A.; Müller, P.; Imberty, A.; Thuenauer, R. et al.; Claudinon, J.; Jumaa, H.; Reth, M.; Eibel, H.; Hobeika, E.; Römer, W.: Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins. Science Signaling 12, p. eaao7194 (2019)
  25. Journal Article
    Mauler, M.; Herr, N.; Schoenichen, C.; Witsch, T.; Marchini, T.; Härdtner, C.; Koentges, C.; Kienle, K.; Ollivier, V.; Schell, M. et al.; Dorner, L.; Wippel, C.; Stallmann, D.; Normann, C.; Bugger, H.; Walther, P.; Wolf, D.; Ahrens, I.; Lämmermann, T.; Ho-Tin-Noé, B.; Ley, K.; Bode, C.; Hilgendorf, I.; Duerschmied, D.: Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation. Circulation 139, pp. 918 - 931 (2019)
  26. Journal Article
    Aprile-Garcia, F.; Parul, T.; Hummel, B.; Khavaran, A.; Sawarkar, R.: Nascent-protein ubiquitination is required for heat shock-induced gene downregulation in human cells. Nature Structural and Molecular Biology 26, pp. 137 - 146 (2019)
  27. Journal Article
    Masuda, T.; Sankowski, R.; Staszewski, O.; Böttcher, C.; Amann, L.; Sagar, S.; Scheiwe, C.; Nessler, S.; Kunz, P.; van Loo, G. et al.; Coenen, V. A.; Reinacher, P. C.; Michel, A.; Sure, U.; Gold, R.; Grün, D.; Priller, J.; Stadelmann, C.; Prinz, M.: Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature 566, pp. 388 - 392 (2019)
  28. Journal Article
    Jordão, M. J. C.; Sankowski, R.; Brendecke, S. M.; Sagar, S.; Locatelli, G.; Tai, Y.-H.; Tay, T. L.; Schramm, E.; Armbruster, S.; Hagemeyer, N. et al.; Groß, O.; Mai, D.; Çiçek, Ö.; Falk, T.; Kerschensteiner, M.; Grün, D.; Prinz, M.: Single-cell profiling identifies myeloid cell subsets with distinct fates during neuro inflammation. Science 363 (2019)
  29. Journal Article
    Nicetto, D.; Donahue, G.; Jain, T.; Peng, T.; Sidoli, S.; Sheng, L.; Montavon, T.; Becker, J. S.; Grindheim, J. M.; Blahnik, K. et al.; Garcia, B. A.; Tan, K.; Bonasio, R.; Jenuwein, T.; Zaret, K. S.: H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science 363, pp. 294 - 297 (2019)
  30. Journal Article
    Assi, S. A.; Imperato, M. R.; Coleman, D. J. L.; Pickin, A.; Potluri, S.; Ptasinska, A.; Chin, P. S.; Blair, H.; Cauchy, P.; James, S. R. et al.; Zacarias-Cabeza, J.; Gilding, L. N.; Beggs, A.; Clokie, S.; Loke, J. C.; Jenkin, P.; Uddin, A.; Delwel, R.; Richards, S. J.; Raghavan, M.; Griffiths, M. J.; Heidenreich, O.; Cockerill, P. N.; Bonifer, C.: Subtype-specific regulatory network rewiring in acute myeloid leukemia. Nature Genetics 51, pp. 151 - 162 (2019)
 
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