Publikationen

Sone, K.; Piao, L.; Nakakido, M.; Ueda, K.; Jenuwein, T.; Nakamura, Y.; Hamamoto, R.: Critical role of lysine 134 methylation on histone H2AX for γ-H2AX production and DNA repair. Nature Communications 5, 5691 (2014), S. 5691 (2014)

Oest, A.; Lempradl, A.; Casas, E.; Weigert, M.; Tiko, T.; Deniz, M.; Pantano, L.; Boenisch, U.; Itskov, P. M.; Stoeckius, M. et al.; Ruf, M.; Rajewsky, N.; Reuter, G.; Iovino, N.; Ribiero, C.; Alenius, M.; Heyne, S.; Vavouri, T.; Pospisilik, J. A.: Paternal Diet Defines Offspring Chromatin State and Intergenerational Obesity. Cell 159, S. 1352 - 1364 (2014)

Xu, X.; Araki, K.; Li, S.; Han, J.-H.; Ye, L.; Tan, W. G.; Konieczny, B. T.; Bruinsma, M. W.; Martinez, J.; Pearce, E. L. et al.; Green, D. R.; Jones, D. P.; Virgin, H. W.; Ahmed, R.; Xu, X.; Araki, K.; Li, S.; Han, J.-H.; Ye, L.; Tan, W. G.; Konieczny, B. T.; Bruinsma, M. W.; Martinez, J.; Pearce, E. L.; Green, D. R.; Jones, D. P.; Ahmed, R.: Autophagy is essential for effector CD8⁺ T cell survival and memory formation. Nature Immunology 15, S. 1152 - 1161 (2014)

O'Sullivan, D.; Pearce, E. L.: Fatty acid sysnthesis tips the TH17-Treg cell balance. Nature Medicine 20, S. 1235 - 1236 (2014)

Walsh, M. C.; Pearce, E. L.; Cejas, P. J.; Lee, J.; Wang, L.-S.; Choi, Y.: IL-18 synergivzes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals. The Journal of Immunology 193, S. 3992 - 4001 (2014)

Das, S.; Li, J.; Holland, S. J.; Iyer, L. M.; Hirano, M.; Schorrp, M.; Aravind, L.; Cooper, M. D.; Boehm, T.: Genomic donor cassette sharing during VLRA and VLRC assembly in jawless vertebrates. Proceedings of the National Academy of Sciences of the United States of America 111, S. 14828 - 14833 (2014)

Holland, S. J.; Gao, M.; Hirano, M.; Iyer, L. M.; Luo, M.; Schorpp, M.; Cooper, M. D.; Aravind, L.; Mariuzza, R. A.; Boehm, T.: Selection of the lamprey VLRC antigen receptor repertoire. Proceedings of the National Academy of Sciences of the United States of America 111, S. 14834 - 14839 (2014)

Amiel, E.; Everts, B.; Fritz, D.; Beauchamp, S.; Ge, B.; Pearce, E. L.; Pearce, E. J.: Mechanistic target of rapamycin inhition extend cellular lifespan in dendritic cells by preserving mitochondrial function. The Journal of Immunology 193, S. 2821 - 2830 (2014)

Eierhoff, T.; Bastian, B.; Thuenauer, R.; Madl, J.; Audfray, A.; Aigal, S.; Juillot, S.; Rydell, G. E.; Müller, S.; de Bentzmann, S. et al.; Imberty, A.; Fleck, C.; Römer, W.: A lipid zipper triggers bacterial invasion. Proceedings of the National Academy of Sciences, USA, S. 12895 - 12900 (2014)

Boller, S.; Grosschedl, R.: The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function. Immunological Reviews 261, S. 102 - 115 (2014)

Chou, C.; Pinto, A. K.; Jonathen, C.; Persaud, S. P.; Cella, M.; Lin, C.-C.; Edelson, B. T.; Allen, P. M.; Colonna, M.; Pearce, E. L. et al.; Diamond, M. S.; Egawa, T.: c-Myc-induced transcription factor AP4 is requeired for host protection mediated by CD8⁺ T Cells. Nature Immunology 15, S. 884 - 893 (2014)

Huang, S. C.-C.; Everts, B.; Ivanova, Y.; O'Sullivan, D.; Nascimento, M.; Smith, A. M.; Beatty, W.; Love-Gregory, L.; Lam, W. Y.; O'Neill, C. M. et al.; Yan, C.; Du, H.; Abumrad, N. A.; Urban, J. F. J.; Artyomov, M. N.; Pearce, E. J.; Pearce, E. L.: Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages. Nature Immunology 15, S. 846 - 855 (2014)

Swann, J. B.; Weyn, A.; Nagakubo, D.; Bleul, C. C.; Toyoda, A.; Happe, C.; Netuschil, N.; Hess, I.; Haas-Assenbaum, A.; Taniguchi, Y. et al.; Schorpp, M.; Boehm, T.: Conversion of the Thymus into a Bipotent Lymphoid Organ by Replacement of Foxn1 with its Paralog Foxn4. Cell Reports 8, S. 1184 - 1197 (2014)

Furdas, S. D.; Hoffmann, I.; Robaa, D.; Herquel, B.; Malinka, W.; Świątek, P.; Akhtar, A.; Sippl, W.; Jung, M.: Pyrido- and benzisothiazolones as inhibitors of histone acetyltransferases (HATs). Medicinal Chemistry Communications 5, S. 1856 - 1862 (2014)

Bulut-Karslioglu, A.; De la Rosa-Velazquez, I. A.; Ramirez, F.; Barenboim, M.; Onishi-Seebacher, M.; Arand, J.; Galán, C.; Winter, G. E.; Engist, B.; Gerle, B. et al.; O'Sullivan, R. J.; Martens, J. H. A.; Walter, J.; Manke, T.; Lachner, M.; Jenuwein, T.: Suv39h-Dependent H3K9me3 Marks Intact Retrotransposons and Silences LINE Elements in Mouse Embryonic Stem Cells. Molecular Cell 55, S. 277 - 290 (2014)

O'Sullivan, D.; van der Windt, G. J.W.; Huang, S. C.-C.; Curtis , J.; Chang, C.-H.; Buck, M. D.; Qiu, J.; Smith, A. M.; Lam, W. Y.; DiPlato, L. M. et al.; Hsu, F.-F.; Birnbaum, M. J.; Pearce, E. J.; Pearce, E. L.: Memory CD8⁺ T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development. Immunity 41, S. 75 - 88 (2014)

Jais, A.; Einwallner, E.; Sharif, O.; Gossens, K.; Tsai-Hsiu Lu, T.; Soyal, S. M.; Medgyesi, D.; Neureiter, D.; Paier-Pourani, J.; Dalgaard, K. et al.; Duvigneau, J. C.; Lindroos-Christensen, J.; Zapf, T.-C.; Amann, S.; Saluzzo, S.; Jantscher, F.; Stiedl, P.; Todoric, J.; Martins, R.; Oberkofler, H.; Müller, S.; Hauser-Kronberger, C.; Kenner, L.; Casanova, E.; Sutterlüty-Fall, H.; Bilban, M.; Miller, K.; Kozlov, A. V.; Krempler, F.; Knapp, S.; Lumeng, C. N.; Patsch, W.; Wagner, O.; Pospisilik, J. A.; Esterbauer, H.: Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man. Cell 158, S. 25 - 40 (2014)

Baracho, G. V.; Cato, M. H.; Zhu, Z.; Jaren, O. R.; Hobeika, E.; Reth, M.; Rickert, R. C.: PDK1 regulates B cell differentiation and homeostasis. Proceedings of the National Academy of Sciences, USA, S. 9573 - 9578 (2014)

Rosenbaum, M.; Andreani, V.; Kapoor, T.; Herp, S.; Flach, H.; Duchniewicz, M.; Grosschedl, R.: MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress. Genes and Development 28, S. 1165 - 1178 (2014)

Venkatesh, B.; Lee, A. P.; Ravi, V.; Maurya, A. K.; Korzh, V.; Lim, Z. W.; Ingham, P. W.; Boehm, T.; Brenner, S.; Warren, W. C.: On the Origin of SCPP genes. Evolution and Development 16, S. 125 - 126 (2014)