Publikationen von W.W.A. Schamel

Bühler, P.; Wolf, P.; Gierschner, D.; Schaber, I.; Katzenwadel, A.; Schulze-Seemann, W.; Wetterauer, U.; Tacke, M.; Swamy, M.; Schamel, W.W.A. et al.; Elsässer-Beile, U.: A bispecific diabody directed against prostate-specific membrane antigen and CD3 induces T-cell mediated lysis of prostate cancer cells. Cancer Immunology and Immunotherapy 57, S. 43 - 52 (2008)

Dopfer, E. P.; Swamy, M.; Siegers, G. M.; Molnar, E.; Yang, J.; Schamel, W. W. A.: Segregation Models. Advances in Experimental Medicine and Biology 640, S. 74 - 81 (2008)

Minguet, S.; Dopfer, E. P.; Pollmer, C.; Freudenberg, M. A.; Galanos, C.; Reth, M.; Huber, M.; Schamel, W. W.: Enhanced B-cell activation mediated by TLR4 and BCR crosstalk. European Journal of Immunology 38, S. 2475 - 2487 (2008)

Minguet, S.; Schamel, W. W. A.: Permissive Geometry Model. Advances in Experimental Medicine and Biology 640, S. 113 - 120 (2008)

Minguet, S.; Swamy, M.; Dopfer, E. P.; Dengler, E.; Alarcón, B.; Schamel, W. W. A.: The extracellular part of ζ is buried in the T cell antigen receptor complex. Immunology Letters 116, S. 203 - 210 (2008)

Minguet, S.; Swamy, M.; Schamel, W. W. A.: The short length of the extracellular domain of ζ is crucial for T cell antigen receptor function. Immunology Letters 116, S. 195 - 202 (2008)

Risueno, R. M.; Schamel, W. W. A.; Alarcón, B.: T Cell Receptor Engagement Triggers Its CD3ε and CD3ζ Subunits to Adopt a Compact, Locked Conformation. PLoS One 3, S. 1 - 9 (2008)

Rosshart, S.; Hofmann, M.; Schweier, O.; Pfaff, A.-K.; Yoshimoto, K.; Takeuchi, T.; Molnar, E.; Schamel, W. W.; Pircher, H.: Interaction of KLRG1 with E-cadherin: New functional and structural insights. European Journal of Immunology 38, S. 3354 - 3364 (2008)

Rossi, N. E.; Reiné, J.; Pineda-Lezamit, M.; Pulgar, M.; Meza, N. W.; Swamy, M.; Risueno, R.; Schamel, W. W. A.; Bonay, P.; Fernández-Malavé, E. et al.; Reguiero, J. R.: Differential antibody binding to the surface αβTCR.CD3 complex of CD4⁺ and CD8⁺ T lymphocytes is conserved in mammals and associated with differential glycosylation. International Immunology 20, S. 1247 - 1258 (2008)

Schamel, W. W. A.; Reth, M.: Clustering Models. Advances in Experimental Medicine and Biology 640, S. 64 - 73 (2008)

Siegers, G.; Fernández-Malavé, E.; Fisch, P.; Regueiro, J. R.; Schamel, W. W. A.: From Structure To Disease: Differential CD3 Usage In The Human and Mouse γδ T Cell Antigen Receptor Determines The Impact Of CD3 Deficiencies On T Cell Development. International Journal of Medical and Biological Frontiers 14, S. 117 - 137 (2008)

Swamy, M.; Dopfer, E. P.; Molnar, E.; Alarcón, B.; Schamel, W. W. A.: The 450 kDa TCR Complex has a Stoichiometry of αβγεδεζζ. Scandanavian Journal of Immunology 67, S. 418 - 420 (2008)

Schamel, W. W. W.: The stoichiometry of the T cell antigen receptor and its implications for the signal transduction mechanism. Signal Transduction 7, S. 311 - 319 (2007)

Schrum, A. G.; Gil, D.; Dopfer, E. P.; Wiest, D. L.; Turka, L. A.; Schamel, W. W. W.; Palmer, E.: High-Sensitivity Detection and Quantitative Analysis of Native Protein-Protein Interactions and Multiprotein Complexes by Flow-Cytometry. Science STKE 389, S. 1 - 12 (2007)

Siegers, G. M.; Swamy, M.; Fernández-Malavé, E.; Minguet, S.; Rathmann, S.; Guardo, A. C.; Pérez-Flores, V.; Regueiro, J. R.; Alarcón, B.; Fisch, P. et al.; Schamel, W. W. A.: Different composition of the human and mouse γδ T cell receptor explains diffferent phenotypes of CD3γ and CD3δ immunodeficiencies. Journal of Experimental Medicine 204, S. 2537 - 2544 (2007)

Swamy, M.; Minguet, S.; Siegers, G. M.; Alarcón, B.; Schamel, W. W. A.: A native antibody-based mobility-shift technique (NAMOS-assay) to determine the stoichiometry of multiprotein complexes. Journal of Immunological Methods 324, S. 74 - 83 (2007)

Fernández-Malavé, E.; Wang, N.; Pulgar, M.; Schamel, W. W. A.; Alarcón, B.; Terhorst, C.: Overlapping functions of human CD3δ and mouse CD3γ in αβ T-cell development revealed in a humanized CD3γ-deficient mouse. Blood 108, S. 3420 - 3427 (2006)

Schamel, W. W. A.; Risueno, R. M.; Minguet, S.; Ortíz, A. R.; Alarcón, B.: A conformation- and avidity-based proofreading mechanism for the TCR-CD3 complex. Trends in Immunology 27, S. 176 - 182 (2006)

Alarcón, B.; Swamy, M.; van Santen, H. M.; Schamel, W. W. A.: T-cell antigen-receptor stoichiometry: pre-clustering for sensitivity. EMBO Reports 7, S. 490 - 495 (2006)

Siegers, G. M.; Yang, J.; Duerr, C. U.; Nielsen, P. J.; Reth, M.; Schamel, W. W. A.: Identification of disulfide bonds in the Ig-α/Ig-β component of the B cell antigen receptor using the Drosophila S2 cell reconstitution system. International Immunology 18, S. 1385 - 1396 (2006)

Swamy, M.; Kulathu, Y.; Ernst, S.; Reth, M.; Schamel, W. W. A.: Two dimensional Blue Native-/SDS-PAGE analysis of SLP family adaptor protein complexes. Immunology Letters 104, S. 131 - 137 (2006)

Swamy, M.; Siegers, G. M.; Minguet, S.; Wollscheid, B.; Schamel, W. W. A.: Blue Native Polyacrylamide Gel Electrophoresis (BN-PAGE) for the Identification and Analysis of Multiprotein Complexes. Science's STKE 345, S. 1 - 14 (2006)

Schamel, W. W. A.; Arechaga, I.; Risueño, R. M.; van Santen, H. M.; Cabezas, P.; Risco, C.; Valpuesta, J. M.; Alarcón, B.: Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response. The Journal of Experimental Medicine 202, S. 493 - 503 (2005)

Heiss, K.; Junkes, C.; Guerreiro, N.; Swamy, M.; Camacho-Carvajal, M. M.; Schamel, W. W. A.; Haidl, I. D.; Wild, D.; Weltzien, H.-U.; Thierse, H.-J.: Subproteomic analysis of metal-interacting proteins in human B cells. Proteomics 5, S. 3614 - 3622 (2005)

Hellwig, S.; Schamel, W. W. A.; Pflugfelder, U.; Gerlich, B.; Weltzien, H.-U.: Differences in pairing and cluster formation of T cell receptor α- and β-chains in T cell clones and fusion hybridomas. Immunobiology 210, S. 685 - 694 (2005)

Minguet, S.; Huber, M.; Rosenkranz, L.; Schamel, W. W. A.; Reth, M.; Brummer, T.: Adenosine and cAMP are potent inhibitors of the NF-κB pathway downstream of immunoreceptors. European Journal of Immunology 35, S. 31 - 41 (2005)

Schamel, W. W. A.; Kuppig, S.; Becker, B.; Gimborn, K.; Hauri, H.-P.; Reth, M.: A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America 100 (17), S. 9861 - 9866 (2003)

Alarcón, B.; Gil, D.; Delgado, P.; Schamel, W. W. A.: Initiation of TCR signaling: regulation within CD3 dimers. Immunological Reviews 191 (1), S. 38 - 46 (2003)

Rolli, V.; Gallwitz, M.; Wossning, T.; Flemming, A.; Schamel, W. W. A.; Zuern, C.; Reth, M.: Amplification of B Cell Antigen Receptor Signaling by a Syk/ITAM Positive Feedback Loop. Molecular Cell 10, S. 1057 - 1069 (2002)

Rolli, V.; Gallwitz, M.; Wossning, T.; Flemming, A.; Schamel, W. W. A.; Zurn, C.; Reth, M.: Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop. Molecular Cell 10 (5), S. 1057 - 1069 (2002)