Publikationen von Rudolf Grosschedl

Chen, H.-R.; Sun, Y.; Mittler, G.; Rumpf, T.; Shvedunova, M.; Grosschedl, R.; Akhtar, A.: MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation. Cell Reports 43, 114682 (2024)

Phongbunchoo, Y.; Braikia, F.-Z.; Pessoa-Rodrigues, C.; Ramamoorthy, S.; Ramachandran, H.; Grosschedl, A.; Ma, F.; Cauchy, P.; Akhtar, A.; Sen, R. et al.; Mittler, G.; Grosschedl, R.: YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment. Cell Reports 43, 114456 (2024)

Zolotarev, N.; Wang, Y.; Du, M.; Bayer, M.; Grosschedl, A.; Cissé, I. I.; Grosschedl, R.: Regularly spaced tyrosines in EBF1 mediate BRG1 recruitment and formation of nuclear subdiffractive clusters. Genes and Development 38, S. 4 - 10 (2024)

Schleussner, N.; Cauchy, P.; Franke, V.; Giefing, M.; Fornes, O.; Vankadari, N.; Assi, S. A.; Costanza, M.; Weniger, M. A.; Akalin, A. et al.; Anagnostopoulos, I.; Bukur, T.; Casarotto, M. G.; Damm, F.; Daumke, O.; Edginton-White, B.; Gebhardt, J. C. M.; Grau, M.; Grunwald, S.; Hansmann, M.-L.; Hartmann, S.; Huber, L.; Kärgel, E.; Lusatis, S.; Noerenberg, D.; Obier, N.; Pannicke, U.; Fischer, A.; Reisser, A.; Rosenwald, A.; Schwarz, K.; Sundararaj, S.; Weilemann, A.; Winkler, W.; Xu, W.; Lenz, G.; Rajewsky, K.; Wasserman, W. W.; Cockerill, P. N.; Scheidereit, C.; Siebert, R.; Küppers, R.; Grosschedl, R.; Janz, M.; Bonifer, C.; Mathas, S.: Transcriptional reprogramming by mutated IRF4 in lymphoma. Nature Communications 14, 6947 (2023)

Grosschedl, R.: Terri Grodzicker: 35 years of shaping scientific publishing and communication. Genes and Development 37, S. 2 - 3 (2023)

Zolotarev, N.; Bayer, M.; Grosschedl, R.: EBF1 is continuously required for stabilizing local chromatin accessibility in pro-B cells. Proceedings of the National Academy of Sciences of the United States of America 119, e2210595119 (2022)

Andreani, V.; Ramamoorthy, S.; Fässler, R.; Grosschedl, R.: Integrin β1 regulates marginal zone B cell differentiation and PI3K signaling. Journal of Experimental Medicine 220, e20220342 (2022)

Bayer, M.; Boller, S.; Ramamoothy, S.; Zolotarev, N.; Cauchy, P.; Iwanami, N.; Mittler, G.; Boehm, T.; Grosschedl, R.: Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling. Genes and Development 36, S. 901 - 915 (2022)

Lenaerts, A.; Kucinski, I.; Deboutte, W.; Derecka, M.; Cauchy, P.; Manke, T.; Göttgens, B.; Grosschedl, R.: EBF1 primes B-lymphoid enhancers and limits the myeloid bias in murine multipotent progenitors. Journal of Experimental Medicine 219, e20212437 (2022)

Qiu, Z.; Guo, W.; Dong, B.; Wang, Y.; Deng, P.; Wang, C.; Liu, J.; Zhang, Q.; Grosschedl, R.; Yu, Z. et al.; Deng, J.; Wu, Y.: EBF1 promotes triple-negative breast cancer progression by surveillance of the HIF1α pathway. Proceedings of the National Academy of Sciences of the United States of America 119, e2119518119 (2022)

Bayer, M.; Grosschedl, R.: How to resist Notch-targeted T-leukemia therapy: Lineage- and MYC enhancer switch. Molecular Cell 82, S. 884 - 886 (2022)

Roy, R.; Ramamoorthy, S.; Shapiro, B. D.; Kaileh, M.; Hernandez, D.; Sarantopoulou, D.; Arepalli, S.; Boller, S.; Singh, A.; Bektas, A. et al.; Kim, J.; Moore, A. Z.; Tanaka, T.; McKelvey, J.; Zukley, L.; Nguyen, C.; Wallace, T.; Dunn, C.; Wersto, R.; Wood, W.; Piao, Y.; Becker, K. G.; Coletta, C.; De, S.; Sen, J. M.; Battle, A.; Weng, N.-p.; Grosschedl, R.; Ferrucci, L.; Sen, R.: DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity. Immunity 54, S. 2465 - 2480 (2021)

Antonio Urrutia, G.; Ramachandran, H.; Cauchy, P.; Boo, K.; Ramamoorthy, S.; Boller, S.; Dogan, E.; Clapes, T.; Trompouki, E.; Torres-Padilla, M.-E. et al.; Palvimo, J. J.; Pichler, A.; Grosschedl, R.: ZFP451-mediated SUMOylation of SATB2 drives embryonic stem cell differentiation. Genes and Development 35, S. 1143 - 1160 (2021)

Wang, Y.; Zolotarev, N.; Yang, C.-Y.; Rambold, A.; Mittler, G.; Grosschedl, R.: A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin. Immunity 53, S. 1151 - 1167 (2020)

Kapoor, T.; Corrado, M.; Pearce, E. L.; Pearce, E. J.; Grosschedl, R.: MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells. Scientific Reports 10, 21626 (2020)

Kucinski, I.; Wilson, N. K.; Hannah, R.; Kinston, S. J.; Cauchy, P.; Lenaerts, A.; Grosschedl, R.; Göttgens, B.: Interactions between lineage-associated transcription factors govern haematopoietic progenitor states. The EMBO Journal 39, e104983 (2020)

Derecka, M.; Herman, J. S.; Cauchy, P.; Ramamoorthy, S.; Lupar, E.; Grün, D.; Grosschedl, R.: EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential. Nature 21, S. 261 - 273 (2020)

Ramamoorthy, S.; Kometani, K.; Herman, J. S.; Bayer, M.; Boller, S.; Edwards-Hicks, J.; Ramachandran, H.; Li, R.; Klein-Geltink, R.; Pearce, E. L. et al.; Grün, D.; Grosschedl, R.: EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism. Genes and Development 34, S. 1503 - 1519 (2020)

Tinterri, A.; Menardy, F.; Diana, M. A.; Lokmane, L.; Keita, M.; Coulpier, F.; Lemoine, S.; Mailhes, C.; Mathieu, B.; Merchan-Sala, P. et al.; Campbell, K.; Gyory, I.; Grosschedl, R.; Popa, D.; Garel, S.: Active intermixing of indirect and direct neurons builds the striatal mosaic. Nature Communications 9, 4725 (2018) (2018)

Yanai, H.; Chiba, S.; Hangai, S.; Kometani, K.; Inoue, A.; Kimura, Y.; Abe, T.; Kiyonari, H.; Nishio, J.; Taguchi-Atarashi, N. et al.; Mizushima, Y.; Negishi, H.; Grosschedl, R.; Taniguchi, T.: Revisiting the role of IRF3 in inflammation and immunity by conditional and specifically targeted gene ablation in mice. Proceedings of the National Academy of Sciences of the United States of America 115, S. 5253 - 5258 (2018)

Boller, S.; Li, R.; Grosschedl, R.: Defining B Cell Chromatin: Lessons from EBF1. Trends in Genetics 34, S. 257 - 269 (2018)

Li , R.; Cauchy, P.; Ramamoorthy, S.; Boller, S.; Chevez, L.; Grosschedl, R.: Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming. Genes and Development 32, S. 96 - 111 (2018)

Andreani, V.; Ramamoorthy, S.; Pandey, A.; Lupar, E.; Nutt, S. L.; Lämmermann, T.; Grosschedl, R.: Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function. Proceedings of the National Academy of Sciences of the United States of America 115, S. E9630 - E9639 (2018)

Musa, Y. R.; Boller, S.; Puchalska, M.; Grosschedl, R.; Mittler, G.: Comprehensive Proteomic Investigation of Ebf1 Heterozygosity in Pro-B Lymphocytes Ulilizing Data Independent Acquisition. Journal of Proteome Research 17, S. 76 - 85 (2018)

Rodríguez-Gil, A.; Ritter, O.; Saul, V. V.; Wilhelm, J.; Yang, C.-Y.; Grosschedl, R.; Imai, Y.; Kuba, K.; Kracht, M.; Schmitz, M. L.: The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription. Scientific Reports 7, 3547 (2017) (2017)

Yang, C.-Y.; Ramamoorthy, S.; Boller, S.; Rosenbaum, M.; Gil, A. R.; Mittler, G.; Imai, Y.; Kuba, K.; Grosschedl, R.: Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis. Genes and Development 30, S. 2310 - 2324 (2016)

Schnappauf, O.; Beyes, S.; Dertmann, A.; Freihen, V.; Frey, P.; Rose, K.; Michoel, T.; Grosschedl, R.; Hecht, A.: Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing. Biochimica et Biophysica Acta (BBA) 1859, S. 1353 - 1367 (2016)

Hilde, K. L.; Levine, A. J.; Hinckley, C. A.; Montgomery, J. M.; Gullo, M.; Driscoll, S. P.; Grosschedl, R.; Kohwi, Y.; Kohwi-Shigematsu, T.; Pfaff, S.: Satb2 Is Required for the Development of a Spinal Exteroceptive Microcircuit that Modulates Limb Position. Neuron 91, S. 763 - 776 (2016)

Boller, S.; Ramamoorthy, S.; Akbas, D.; Nechanitzky, R.; Burger, L.; Murr, R.; Schübeler, D.; Grosschedl, R.: Pioneering Activity of the C-Terminal Domain of EBF1 Shapes the Chromatin Landscape for B Cell Programming. Immunity 44, S. 527 - 541 (2016)

Leone, D. P.; Heavner, W. E.; Ferenczi, E. A.; Dobreva, G.; Huguendard, J. R.; Grosschedl, R.; McConnell, S. K.: Satb2 Regulates the differntiationof Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex. Cerebral Cortex 25, S. 3406 - 3419 (2015)